VSIG10 protein (human) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

VSIG10

V-set and immunoglobulin domain containing 10. (540 aa)

Predicted Functional Partners:

ANKRD13D

0.558

LRRC73

0.556

TEPSIN

0.531

TTC17

0.516

WSB2

0.511

ZNF654

0.507

OR2I1P

0.480

FAM174A

0.452

ST3GAL5

0.447

HEATR5B

0.433

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANKRD13D	LRRC73	ENSP00000427130	ENSP00000361518	Ankyrin repeat domain-containing protein 13D; Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.	Leucine-rich repeat-containing protein 73; Leucine rich repeat containing 73.	0.665
ANKRD13D	TEPSIN	ENSP00000427130	ENSP00000490393	Ankyrin repeat domain-containing protein 13D; Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.	AP-4 complex accessory subunit Tepsin; Associates with the adapter-like complex 4 (AP-4) and may therefore play a role in vesicular trafficking of proteins at the trans-Golgi network.	0.644
ANKRD13D	VSIG10	ENSP00000427130	ENSP00000352172	Ankyrin repeat domain-containing protein 13D; Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.	V-set and immunoglobulin domain containing 10.	0.558
FAM174A	HEATR5B	ENSP00000307954	ENSP00000233099	Membrane protein FAM174A; Family with sequence similarity 174 member A.	HEAT repeat containing 5B; Belongs to the HEATR5 family.	0.456
FAM174A	TTC17	ENSP00000307954	ENSP00000039989	Membrane protein FAM174A; Family with sequence similarity 174 member A.	Tetratricopeptide repeat protein 17; Plays a role in primary ciliogenesis by modulating actin polymerization.	0.411
FAM174A	VSIG10	ENSP00000307954	ENSP00000352172	Membrane protein FAM174A; Family with sequence similarity 174 member A.	V-set and immunoglobulin domain containing 10.	0.452
HEATR5B	FAM174A	ENSP00000233099	ENSP00000307954	HEAT repeat containing 5B; Belongs to the HEATR5 family.	Membrane protein FAM174A; Family with sequence similarity 174 member A.	0.456
HEATR5B	TTC17	ENSP00000233099	ENSP00000039989	HEAT repeat containing 5B; Belongs to the HEATR5 family.	Tetratricopeptide repeat protein 17; Plays a role in primary ciliogenesis by modulating actin polymerization.	0.516
HEATR5B	VSIG10	ENSP00000233099	ENSP00000352172	HEAT repeat containing 5B; Belongs to the HEATR5 family.	V-set and immunoglobulin domain containing 10.	0.433
LRRC73	ANKRD13D	ENSP00000361518	ENSP00000427130	Leucine-rich repeat-containing protein 73; Leucine rich repeat containing 73.	Ankyrin repeat domain-containing protein 13D; Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.	0.665
LRRC73	TEPSIN	ENSP00000361518	ENSP00000490393	Leucine-rich repeat-containing protein 73; Leucine rich repeat containing 73.	AP-4 complex accessory subunit Tepsin; Associates with the adapter-like complex 4 (AP-4) and may therefore play a role in vesicular trafficking of proteins at the trans-Golgi network.	0.625
LRRC73	VSIG10	ENSP00000361518	ENSP00000352172	Leucine-rich repeat-containing protein 73; Leucine rich repeat containing 73.	V-set and immunoglobulin domain containing 10.	0.556
OR2I1P	VSIG10	ENSP00000493715	ENSP00000352172	Putative olfactory receptor 2I1; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.	V-set and immunoglobulin domain containing 10.	0.480
ST3GAL5	VSIG10	ENSP00000491316	ENSP00000352172	Lactosylceramide alpha-2,3-sialyltransferase; Catalyzes the formation of ganglioside GM3 (alpha-N- acetylneuraminyl-2,3-beta-D-galactosyl-1, 4-beta-D-glucosylceramide).	V-set and immunoglobulin domain containing 10.	0.447
TEPSIN	ANKRD13D	ENSP00000490393	ENSP00000427130	AP-4 complex accessory subunit Tepsin; Associates with the adapter-like complex 4 (AP-4) and may therefore play a role in vesicular trafficking of proteins at the trans-Golgi network.	Ankyrin repeat domain-containing protein 13D; Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.	0.644
TEPSIN	LRRC73	ENSP00000490393	ENSP00000361518	AP-4 complex accessory subunit Tepsin; Associates with the adapter-like complex 4 (AP-4) and may therefore play a role in vesicular trafficking of proteins at the trans-Golgi network.	Leucine-rich repeat-containing protein 73; Leucine rich repeat containing 73.	0.625
TEPSIN	VSIG10	ENSP00000490393	ENSP00000352172	AP-4 complex accessory subunit Tepsin; Associates with the adapter-like complex 4 (AP-4) and may therefore play a role in vesicular trafficking of proteins at the trans-Golgi network.	V-set and immunoglobulin domain containing 10.	0.531
TTC17	FAM174A	ENSP00000039989	ENSP00000307954	Tetratricopeptide repeat protein 17; Plays a role in primary ciliogenesis by modulating actin polymerization.	Membrane protein FAM174A; Family with sequence similarity 174 member A.	0.411
TTC17	HEATR5B	ENSP00000039989	ENSP00000233099	Tetratricopeptide repeat protein 17; Plays a role in primary ciliogenesis by modulating actin polymerization.	HEAT repeat containing 5B; Belongs to the HEATR5 family.	0.516
TTC17	VSIG10	ENSP00000039989	ENSP00000352172	Tetratricopeptide repeat protein 17; Plays a role in primary ciliogenesis by modulating actin polymerization.	V-set and immunoglobulin domain containing 10.	0.516