node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCDC116 | YDJC | ENSP00000292779 | ENSP00000292778 | Coiled-coil domain containing 116. | Carbohydrate deacetylase; Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides. Belongs to the YdjC deacetylase family. | 0.500 |
CDC16 | YDJC | ENSP00000348554 | ENSP00000292778 | Cell division cycle protein 16 homolog; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Belongs to the APC6/CDC16 family. | Carbohydrate deacetylase; Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides. Belongs to the YdjC deacetylase family. | 0.566 |
H7C0V5_HUMAN | YDJC | ENSP00000432016 | ENSP00000292778 | ANKHD1-EIF4EBP3 readthrough. | Carbohydrate deacetylase; Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides. Belongs to the YdjC deacetylase family. | 0.432 |
LRRC14 | PUSL1 | ENSP00000292524 | ENSP00000368318 | Leucine-rich repeat-containing protein 14; Negatively regulates Toll-like receptor-mediated NF-kappa-B signaling by disrupting IKK core complex formation through interaction with IKBKB; Belongs to the PRAME family. LRRC14 subfamily. | Pseudouridine synthase like 1; Belongs to the tRNA pseudouridine synthase TruA family. | 0.433 |
LRRC14 | YDJC | ENSP00000292524 | ENSP00000292778 | Leucine-rich repeat-containing protein 14; Negatively regulates Toll-like receptor-mediated NF-kappa-B signaling by disrupting IKK core complex formation through interaction with IKBKB; Belongs to the PRAME family. LRRC14 subfamily. | Carbohydrate deacetylase; Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides. Belongs to the YdjC deacetylase family. | 0.588 |
PCMT1 | YDJC | ENSP00000497225 | ENSP00000292778 | Protein-L-isoaspartate(D-aspartate) O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl and D- aspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins. Acts on EIF4EBP2, microtubule-associated protein 2, calreticulin, clathrin light chains a and b, Ubiquitin carboxyl-terminal hydrolase isozyme L1, phosphatidylethanolamine-binding protein 1, stathmin, beta-synuclein and alpha-synuclein. | Carbohydrate deacetylase; Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides. Belongs to the YdjC deacetylase family. | 0.465 |
PRAME | YDJC | ENSP00000445675 | ENSP00000292778 | Melanoma antigen preferentially expressed in tumors; Functions as a transcriptional repressor, inhibiting the signaling of retinoic acid through the retinoic acid receptors RARA, RARB and RARG. Prevents retinoic acid-induced cell proliferation arrest, differentiation and apoptosis. | Carbohydrate deacetylase; Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides. Belongs to the YdjC deacetylase family. | 0.485 |
PUSL1 | LRRC14 | ENSP00000368318 | ENSP00000292524 | Pseudouridine synthase like 1; Belongs to the tRNA pseudouridine synthase TruA family. | Leucine-rich repeat-containing protein 14; Negatively regulates Toll-like receptor-mediated NF-kappa-B signaling by disrupting IKK core complex formation through interaction with IKBKB; Belongs to the PRAME family. LRRC14 subfamily. | 0.433 |
PUSL1 | RPUSD1 | ENSP00000368318 | ENSP00000455026 | Pseudouridine synthase like 1; Belongs to the tRNA pseudouridine synthase TruA family. | RNA pseudouridine synthase domain containing 1; Belongs to the pseudouridine synthase RluA family. | 0.909 |
PUSL1 | YDJC | ENSP00000368318 | ENSP00000292778 | Pseudouridine synthase like 1; Belongs to the tRNA pseudouridine synthase TruA family. | Carbohydrate deacetylase; Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides. Belongs to the YdjC deacetylase family. | 0.543 |
RPUSD1 | PUSL1 | ENSP00000455026 | ENSP00000368318 | RNA pseudouridine synthase domain containing 1; Belongs to the pseudouridine synthase RluA family. | Pseudouridine synthase like 1; Belongs to the tRNA pseudouridine synthase TruA family. | 0.909 |
RPUSD1 | YDJC | ENSP00000455026 | ENSP00000292778 | RNA pseudouridine synthase domain containing 1; Belongs to the pseudouridine synthase RluA family. | Carbohydrate deacetylase; Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides. Belongs to the YdjC deacetylase family. | 0.441 |
UBE2L3 | YDJC | ENSP00000400906 | ENSP00000292778 | Ubiquitin conjugating enzyme E2 L3. | Carbohydrate deacetylase; Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides. Belongs to the YdjC deacetylase family. | 0.693 |
UBE2L3 | ZMIZ1 | ENSP00000400906 | ENSP00000334474 | Ubiquitin conjugating enzyme E2 L3. | Zinc finger MIZ domain-containing protein 1; Acts as transcriptional coactivator. Increases ligand- dependent transcriptional activity of AR and promotes AR sumoylation. The stimulation of AR activity is dependent upon sumoylation. Also functions as a transcriptional coactivator in the TGF-beta signaling pathway by increasing the activity of the SMAD3/SMAD4 transcriptional complex. Involved in transcriptional activation of a subset of NOTCH1 target genes including MYC. Involved in thymocyte and T cell development (By similarity). | 0.493 |
YDJC | CCDC116 | ENSP00000292778 | ENSP00000292779 | Carbohydrate deacetylase; Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides. Belongs to the YdjC deacetylase family. | Coiled-coil domain containing 116. | 0.500 |
YDJC | CDC16 | ENSP00000292778 | ENSP00000348554 | Carbohydrate deacetylase; Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides. Belongs to the YdjC deacetylase family. | Cell division cycle protein 16 homolog; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Belongs to the APC6/CDC16 family. | 0.566 |
YDJC | H7C0V5_HUMAN | ENSP00000292778 | ENSP00000432016 | Carbohydrate deacetylase; Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides. Belongs to the YdjC deacetylase family. | ANKHD1-EIF4EBP3 readthrough. | 0.432 |
YDJC | LRRC14 | ENSP00000292778 | ENSP00000292524 | Carbohydrate deacetylase; Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides. Belongs to the YdjC deacetylase family. | Leucine-rich repeat-containing protein 14; Negatively regulates Toll-like receptor-mediated NF-kappa-B signaling by disrupting IKK core complex formation through interaction with IKBKB; Belongs to the PRAME family. LRRC14 subfamily. | 0.588 |
YDJC | PCMT1 | ENSP00000292778 | ENSP00000497225 | Carbohydrate deacetylase; Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides. Belongs to the YdjC deacetylase family. | Protein-L-isoaspartate(D-aspartate) O-methyltransferase; Catalyzes the methyl esterification of L-isoaspartyl and D- aspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins. Acts on EIF4EBP2, microtubule-associated protein 2, calreticulin, clathrin light chains a and b, Ubiquitin carboxyl-terminal hydrolase isozyme L1, phosphatidylethanolamine-binding protein 1, stathmin, beta-synuclein and alpha-synuclein. | 0.465 |
YDJC | PRAME | ENSP00000292778 | ENSP00000445675 | Carbohydrate deacetylase; Probably catalyzes the deacetylation of acetylated carbohydrates an important step in the degradation of oligosaccharides. Belongs to the YdjC deacetylase family. | Melanoma antigen preferentially expressed in tumors; Functions as a transcriptional repressor, inhibiting the signaling of retinoic acid through the retinoic acid receptors RARA, RARB and RARG. Prevents retinoic acid-induced cell proliferation arrest, differentiation and apoptosis. | 0.485 |