STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
YIPF4Protein YIPF4; Involved in the maintenance of the Golgi structure. Belongs to the YIP1 family. (244 aa)    
Predicted Functional Partners:
YIPF3
Protein YIPF3, 36 kDa form III; Involved in the maintenance of the Golgi structure. May play a role in hematopoiesis.
   
 
 0.965
YIF1A
Protein YIF1A; Possible role in transport between endoplasmic reticulum and Golgi; Belongs to the YIF1 family.
   
 
 0.838
YIPF2
Protein YIPF2; Yip1 domain family member 2.
   
 
 0.787
YIPF1
Protein YIPF1; Yip1 domain family member 1; Belongs to the YIP1 family.
   
 
 0.711
YIF1B
Protein YIF1B; Yip1 interacting factor homolog B, membrane trafficking protein.
   
 
 0.674
ZNF324B
Zinc finger protein 324B; May be involved in transcriptional regulation.
      
 0.540
IER3IP1
Immediate early response 3-interacting protein 1; May be implicated in the regulation of apoptosis. May be involved in protein transport between endoplasmic reticulum and Golgi apparatus (By similarity); Belongs to the YOS1 family.
   
 
 0.533
FRMD5
FERM domain-containing protein 5; May be involved in regulation of cell migration. May regulate cell-matrix interactions via its interaction with ITGB5 and modifying ITGB5 cytoplasmic tail interactions such as with FERMT2 and TLN1. May regulate ROCK1 kinase activity possibly involved in regulation of actin stress fiber formation.
   
  
 0.483
ZNF26
Zinc finger protein 26; May be involved in transcriptional regulation.
   
    0.453
TMPPE
Transmembrane protein with metallophosphoesterase domain.
      
 0.451
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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