node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AOC1 | ZC3H10 | ENSP00000411613 | ENSP00000257940 | Amiloride-sensitive amine oxidase [copper-containing]; Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. Placental DAO is thought to play a role in the regulation of the female reproductive function; Belongs to the copper/topaquinone oxidase family. | Zinc finger CCCH domain-containing protein 10; Specific regulator of miRNA biogenesis. Binds, via the C3H1- type zinc finger domains, to the binding motif 5'-GCAGCGC-3' on microRNA pri-MIR143 and negatively regulates the processing to mature microRNA. | 0.526 |
BCDIN3D | ZC3H10 | ENSP00000335201 | ENSP00000257940 | RNA 5'-monophosphate methyltransferase; O-methyltransferase that specifically monomethylates 5'- monophosphate of cytoplasmic histidyl tRNA, acting as a capping enzyme. Less efficiently, also methylates the 5' monophosphate of pre-miRNAs, acting as a negative regulator of miRNA processing. The 5' monophosphate of pre-miRNAs is recognized by DICER1 and is required for pre-miRNAs processing: methylation at this position reduces the processing of pre- miRNAs by DICER1. Able to mediate methylation of pre-miR-145, as well as other pre-miRNAs. There is some controversy about the methylation [...] | Zinc finger CCCH domain-containing protein 10; Specific regulator of miRNA biogenesis. Binds, via the C3H1- type zinc finger domains, to the binding motif 5'-GCAGCGC-3' on microRNA pri-MIR143 and negatively regulates the processing to mature microRNA. | 0.539 |
CBLN3 | CCDC137 | ENSP00000267406 | ENSP00000329360 | Cerebellin-3; May be involved in synaptic functions in the CNS. | Coiled-coil domain containing 137. | 0.573 |
CBLN3 | CLEC19A | ENSP00000267406 | ENSP00000490375 | Cerebellin-3; May be involved in synaptic functions in the CNS. | C-type lectin domain containing 19A. | 0.556 |
CBLN3 | LAMB4 | ENSP00000267406 | ENSP00000373433 | Cerebellin-3; May be involved in synaptic functions in the CNS. | Laminin subunit beta-4; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. | 0.439 |
CBLN3 | TMEM69 | ENSP00000267406 | ENSP00000361095 | Cerebellin-3; May be involved in synaptic functions in the CNS. | Transmembrane protein 69. | 0.581 |
CBLN3 | ZC3H10 | ENSP00000267406 | ENSP00000257940 | Cerebellin-3; May be involved in synaptic functions in the CNS. | Zinc finger CCCH domain-containing protein 10; Specific regulator of miRNA biogenesis. Binds, via the C3H1- type zinc finger domains, to the binding motif 5'-GCAGCGC-3' on microRNA pri-MIR143 and negatively regulates the processing to mature microRNA. | 0.533 |
CCDC137 | CBLN3 | ENSP00000329360 | ENSP00000267406 | Coiled-coil domain containing 137. | Cerebellin-3; May be involved in synaptic functions in the CNS. | 0.573 |
CCDC137 | CLEC19A | ENSP00000329360 | ENSP00000490375 | Coiled-coil domain containing 137. | C-type lectin domain containing 19A. | 0.532 |
CCDC137 | PLTP | ENSP00000329360 | ENSP00000417138 | Coiled-coil domain containing 137. | Phospholipid transfer protein; Facilitates the transfer of a spectrum of different lipid molecules, including diacylglycerol, phosphatidic acid, sphingomyelin, phosphatidylcholine, phosphatidylglycerol, cerebroside and phosphatidyl ethanolamine. Essential for the transfer of excess surface lipids from triglyceride-rich lipoproteins to HDL, thereby facilitating the formation of smaller lipoprotein remnants, contributing to the formation of LDL, and assisting in the maturation of HDL particles. PLTP also plays a key role in the uptake of cholesterol from peripheral cells and tissues that [...] | 0.439 |
CCDC137 | TMEM69 | ENSP00000329360 | ENSP00000361095 | Coiled-coil domain containing 137. | Transmembrane protein 69. | 0.652 |
CCDC137 | ZC3H10 | ENSP00000329360 | ENSP00000257940 | Coiled-coil domain containing 137. | Zinc finger CCCH domain-containing protein 10; Specific regulator of miRNA biogenesis. Binds, via the C3H1- type zinc finger domains, to the binding motif 5'-GCAGCGC-3' on microRNA pri-MIR143 and negatively regulates the processing to mature microRNA. | 0.630 |
CLEC19A | CBLN3 | ENSP00000490375 | ENSP00000267406 | C-type lectin domain containing 19A. | Cerebellin-3; May be involved in synaptic functions in the CNS. | 0.556 |
CLEC19A | CCDC137 | ENSP00000490375 | ENSP00000329360 | C-type lectin domain containing 19A. | Coiled-coil domain containing 137. | 0.532 |
CLEC19A | LAMB4 | ENSP00000490375 | ENSP00000373433 | C-type lectin domain containing 19A. | Laminin subunit beta-4; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. | 0.427 |
CLEC19A | TMEM69 | ENSP00000490375 | ENSP00000361095 | C-type lectin domain containing 19A. | Transmembrane protein 69. | 0.549 |
CLEC19A | ZC3H10 | ENSP00000490375 | ENSP00000257940 | C-type lectin domain containing 19A. | Zinc finger CCCH domain-containing protein 10; Specific regulator of miRNA biogenesis. Binds, via the C3H1- type zinc finger domains, to the binding motif 5'-GCAGCGC-3' on microRNA pri-MIR143 and negatively regulates the processing to mature microRNA. | 0.559 |
ESYT1 | ZC3H10 | ENSP00000267113 | ENSP00000257940 | Extended synaptotagmin-1; Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport (By similarity). Binds calcium (via the C2 domains) and translocates to sites of contact between the endoplasmic reticulum and the cell membrane in response to increased cytosolic calcium levels. Helps tether the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane; Belongs to the extended synaptotagmin family. | Zinc finger CCCH domain-containing protein 10; Specific regulator of miRNA biogenesis. Binds, via the C3H1- type zinc finger domains, to the binding motif 5'-GCAGCGC-3' on microRNA pri-MIR143 and negatively regulates the processing to mature microRNA. | 0.486 |
LAMB4 | CBLN3 | ENSP00000373433 | ENSP00000267406 | Laminin subunit beta-4; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. | Cerebellin-3; May be involved in synaptic functions in the CNS. | 0.439 |
LAMB4 | CLEC19A | ENSP00000373433 | ENSP00000490375 | Laminin subunit beta-4; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. | C-type lectin domain containing 19A. | 0.427 |