node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
NKAPL | PGBD1 | ENSP00000345716 | ENSP00000259883 | NKAP-like protein; Transcriptional repressor of Notch-mediated signaling. Required for spermatogenesis. | piggyBac transposable element derived 1. | 0.596 |
NKAPL | ZKSCAN4 | ENSP00000345716 | ENSP00000366509 | NKAP-like protein; Transcriptional repressor of Notch-mediated signaling. Required for spermatogenesis. | Zinc finger protein with KRAB and SCAN domains 4; May be involved in the transcriptional activation of MDM2 and EP300 genes; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.722 |
NKAPL | ZKSCAN8 | ENSP00000345716 | ENSP00000332750 | NKAP-like protein; Transcriptional repressor of Notch-mediated signaling. Required for spermatogenesis. | Zinc finger protein with KRAB and SCAN domains 8; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.645 |
PGBD1 | NKAPL | ENSP00000259883 | ENSP00000345716 | piggyBac transposable element derived 1. | NKAP-like protein; Transcriptional repressor of Notch-mediated signaling. Required for spermatogenesis. | 0.596 |
PGBD1 | ZKSCAN4 | ENSP00000259883 | ENSP00000366509 | piggyBac transposable element derived 1. | Zinc finger protein with KRAB and SCAN domains 4; May be involved in the transcriptional activation of MDM2 and EP300 genes; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.840 |
PGBD1 | ZKSCAN8 | ENSP00000259883 | ENSP00000332750 | piggyBac transposable element derived 1. | Zinc finger protein with KRAB and SCAN domains 8; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.704 |
PGBD1 | ZNF396 | ENSP00000259883 | ENSP00000466500 | piggyBac transposable element derived 1. | Zinc finger protein 396; Isoform 1 and isoform 2 act as DNA-dependent transcriptional repressors. | 0.831 |
PGBD1 | ZNF397 | ENSP00000259883 | ENSP00000331577 | piggyBac transposable element derived 1. | Zinc finger protein 397; Isoform 3 acts as a DNA-dependent transcriptional repressor. | 0.785 |
PGBD1 | ZSCAN20 | ENSP00000259883 | ENSP00000355053 | piggyBac transposable element derived 1. | Zinc finger and SCAN domain-containing protein 20; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.787 |
PGBD1 | ZSCAN32 | ENSP00000259883 | ENSP00000380061 | piggyBac transposable element derived 1. | Zinc finger and SCAN domain-containing protein 32; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.828 |
TRIM28 | ZKSCAN4 | ENSP00000253024 | ENSP00000366509 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein with KRAB and SCAN domains 4; May be involved in the transcriptional activation of MDM2 and EP300 genes; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.581 |
TRIM28 | ZKSCAN8 | ENSP00000253024 | ENSP00000332750 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein with KRAB and SCAN domains 8; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.659 |
TRIM28 | ZNF483 | ENSP00000253024 | ENSP00000311679 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 483; May be involved in transcriptional regulation. | 0.625 |
TRIM28 | ZSCAN32 | ENSP00000253024 | ENSP00000380061 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger and SCAN domain-containing protein 32; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.522 |
ZKSCAN4 | NKAPL | ENSP00000366509 | ENSP00000345716 | Zinc finger protein with KRAB and SCAN domains 4; May be involved in the transcriptional activation of MDM2 and EP300 genes; Belongs to the krueppel C2H2-type zinc-finger protein family. | NKAP-like protein; Transcriptional repressor of Notch-mediated signaling. Required for spermatogenesis. | 0.722 |
ZKSCAN4 | PGBD1 | ENSP00000366509 | ENSP00000259883 | Zinc finger protein with KRAB and SCAN domains 4; May be involved in the transcriptional activation of MDM2 and EP300 genes; Belongs to the krueppel C2H2-type zinc-finger protein family. | piggyBac transposable element derived 1. | 0.840 |
ZKSCAN4 | TRIM28 | ENSP00000366509 | ENSP00000253024 | Zinc finger protein with KRAB and SCAN domains 4; May be involved in the transcriptional activation of MDM2 and EP300 genes; Belongs to the krueppel C2H2-type zinc-finger protein family. | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | 0.581 |
ZKSCAN4 | ZKSCAN8 | ENSP00000366509 | ENSP00000332750 | Zinc finger protein with KRAB and SCAN domains 4; May be involved in the transcriptional activation of MDM2 and EP300 genes; Belongs to the krueppel C2H2-type zinc-finger protein family. | Zinc finger protein with KRAB and SCAN domains 8; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.747 |
ZKSCAN4 | ZNF396 | ENSP00000366509 | ENSP00000466500 | Zinc finger protein with KRAB and SCAN domains 4; May be involved in the transcriptional activation of MDM2 and EP300 genes; Belongs to the krueppel C2H2-type zinc-finger protein family. | Zinc finger protein 396; Isoform 1 and isoform 2 act as DNA-dependent transcriptional repressors. | 0.835 |
ZKSCAN4 | ZNF397 | ENSP00000366509 | ENSP00000331577 | Zinc finger protein with KRAB and SCAN domains 4; May be involved in the transcriptional activation of MDM2 and EP300 genes; Belongs to the krueppel C2H2-type zinc-finger protein family. | Zinc finger protein 397; Isoform 3 acts as a DNA-dependent transcriptional repressor. | 0.840 |