node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AMBRA1 | ZNF142 | ENSP00000431926 | ENSP00000398798 | Activating molecule in BECN1-regulated autophagy protein 1; Regulates autophagy and development of the nervous system. Involved in autophagy in controlling protein turnover during neuronal development, and in regulating normal cell survival and proliferation (By similarity). | Zinc finger protein 142; May be involved in transcriptional regulation. | 0.573 |
ANKRD52 | ZNF142 | ENSP00000267116 | ENSP00000398798 | Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C; Putative regulatory subunit of protein phosphatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates. | Zinc finger protein 142; May be involved in transcriptional regulation. | 0.504 |
C16orf96 | GLB1L | ENSP00000415027 | ENSP00000295759 | Uncharacterized protein C16orf96; Chromosome 16 open reading frame 96. | Beta-galactosidase-1-like protein; Probable glycosyl hydrolase. | 0.516 |
C16orf96 | ZNF142 | ENSP00000415027 | ENSP00000398798 | Uncharacterized protein C16orf96; Chromosome 16 open reading frame 96. | Zinc finger protein 142; May be involved in transcriptional regulation. | 0.634 |
EDC4 | ZNF142 | ENSP00000351811 | ENSP00000398798 | Enhancer of mRNA-decapping protein 4; In the process of mRNA degradation, seems to play a role in mRNA decapping. Component of a complex containing DCP2 and DCP1A which functions in decapping of ARE-containing mRNAs. Promotes complex formation between DCP1A and DCP2. Enhances the catalytic activity of DCP2 (in vitro). | Zinc finger protein 142; May be involved in transcriptional regulation. | 0.479 |
GLB1L | C16orf96 | ENSP00000295759 | ENSP00000415027 | Beta-galactosidase-1-like protein; Probable glycosyl hydrolase. | Uncharacterized protein C16orf96; Chromosome 16 open reading frame 96. | 0.516 |
GLB1L | ZNF142 | ENSP00000295759 | ENSP00000398798 | Beta-galactosidase-1-like protein; Probable glycosyl hydrolase. | Zinc finger protein 142; May be involved in transcriptional regulation. | 0.483 |
MRPS16 | ZNF142 | ENSP00000362036 | ENSP00000398798 | Mitochondrial ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family. | Zinc finger protein 142; May be involved in transcriptional regulation. | 0.481 |
RUFY4 | STK36 | ENSP00000363270 | ENSP00000295709 | RUN and FYVE domain-containing protein 4; Positively regulates macroautophagy in primary dendritic cells. Increases autophagic flux, probably by stimulating both autophagosome formation and facilitating tethering with lysosomes. Binds to phosphatidylinositol 3-phosphate (PtdIns3P) through its FYVE- type zinc finger. | Serine/threonine-protein kinase 36; Serine/threonine protein kinase which plays an important role in the sonic hedgehog (Shh) pathway by regulating the activity of GLI transcription factors. Controls the activity of the transcriptional regulators GLI1, GLI2 and GLI3 by opposing the effect of SUFU and promoting their nuclear localization. GLI2 requires an additional function of STK36 to become transcriptionally active, but the enzyme does not need to possess an active kinase catalytic site for this to occur. Required for postnatal development, possibly by regulating the homeostasis of c [...] | 0.432 |
RUFY4 | ZNF142 | ENSP00000363270 | ENSP00000398798 | RUN and FYVE domain-containing protein 4; Positively regulates macroautophagy in primary dendritic cells. Increases autophagic flux, probably by stimulating both autophagosome formation and facilitating tethering with lysosomes. Binds to phosphatidylinositol 3-phosphate (PtdIns3P) through its FYVE- type zinc finger. | Zinc finger protein 142; May be involved in transcriptional regulation. | 0.532 |
SNAPC4 | ZNF142 | ENSP00000298532 | ENSP00000398798 | snRNA-activating protein complex subunit 4; Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box. | Zinc finger protein 142; May be involved in transcriptional regulation. | 0.476 |
STK36 | RUFY4 | ENSP00000295709 | ENSP00000363270 | Serine/threonine-protein kinase 36; Serine/threonine protein kinase which plays an important role in the sonic hedgehog (Shh) pathway by regulating the activity of GLI transcription factors. Controls the activity of the transcriptional regulators GLI1, GLI2 and GLI3 by opposing the effect of SUFU and promoting their nuclear localization. GLI2 requires an additional function of STK36 to become transcriptionally active, but the enzyme does not need to possess an active kinase catalytic site for this to occur. Required for postnatal development, possibly by regulating the homeostasis of c [...] | RUN and FYVE domain-containing protein 4; Positively regulates macroautophagy in primary dendritic cells. Increases autophagic flux, probably by stimulating both autophagosome formation and facilitating tethering with lysosomes. Binds to phosphatidylinositol 3-phosphate (PtdIns3P) through its FYVE- type zinc finger. | 0.432 |
STK36 | ZNF142 | ENSP00000295709 | ENSP00000398798 | Serine/threonine-protein kinase 36; Serine/threonine protein kinase which plays an important role in the sonic hedgehog (Shh) pathway by regulating the activity of GLI transcription factors. Controls the activity of the transcriptional regulators GLI1, GLI2 and GLI3 by opposing the effect of SUFU and promoting their nuclear localization. GLI2 requires an additional function of STK36 to become transcriptionally active, but the enzyme does not need to possess an active kinase catalytic site for this to occur. Required for postnatal development, possibly by regulating the homeostasis of c [...] | Zinc finger protein 142; May be involved in transcriptional regulation. | 0.522 |
ZBTB40 | ZNF142 | ENSP00000384527 | ENSP00000398798 | Zinc finger and BTB domain-containing protein 40; May be involved in transcriptional regulation. | Zinc finger protein 142; May be involved in transcriptional regulation. | 0.487 |
ZNF142 | AMBRA1 | ENSP00000398798 | ENSP00000431926 | Zinc finger protein 142; May be involved in transcriptional regulation. | Activating molecule in BECN1-regulated autophagy protein 1; Regulates autophagy and development of the nervous system. Involved in autophagy in controlling protein turnover during neuronal development, and in regulating normal cell survival and proliferation (By similarity). | 0.573 |
ZNF142 | ANKRD52 | ENSP00000398798 | ENSP00000267116 | Zinc finger protein 142; May be involved in transcriptional regulation. | Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C; Putative regulatory subunit of protein phosphatase 6 (PP6) that may be involved in the recognition of phosphoprotein substrates. | 0.504 |
ZNF142 | C16orf96 | ENSP00000398798 | ENSP00000415027 | Zinc finger protein 142; May be involved in transcriptional regulation. | Uncharacterized protein C16orf96; Chromosome 16 open reading frame 96. | 0.634 |
ZNF142 | EDC4 | ENSP00000398798 | ENSP00000351811 | Zinc finger protein 142; May be involved in transcriptional regulation. | Enhancer of mRNA-decapping protein 4; In the process of mRNA degradation, seems to play a role in mRNA decapping. Component of a complex containing DCP2 and DCP1A which functions in decapping of ARE-containing mRNAs. Promotes complex formation between DCP1A and DCP2. Enhances the catalytic activity of DCP2 (in vitro). | 0.479 |
ZNF142 | GLB1L | ENSP00000398798 | ENSP00000295759 | Zinc finger protein 142; May be involved in transcriptional regulation. | Beta-galactosidase-1-like protein; Probable glycosyl hydrolase. | 0.483 |
ZNF142 | MRPS16 | ENSP00000398798 | ENSP00000362036 | Zinc finger protein 142; May be involved in transcriptional regulation. | Mitochondrial ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family. | 0.481 |