node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCNI2 | ZNF253 | ENSP00000478257 | ENSP00000468720 | Cyclin-I2; Cyclin I family member 2. | Zinc finger protein 253; May function as a transcription factor. Seem to have a transcriptional repression activity; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.450 |
CCNI2 | ZNF254 | ENSP00000478257 | ENSP00000349494 | Cyclin-I2; Cyclin I family member 2. | Zinc finger protein 254; May be involved in transcriptional regulation. | 0.406 |
FAM124B | ZNF254 | ENSP00000386895 | ENSP00000349494 | Protein FAM124B; Family with sequence similarity 124 member B; Belongs to the FAM124 family. | Zinc finger protein 254; May be involved in transcriptional regulation. | 0.420 |
ICA1 | ZNF254 | ENSP00000403982 | ENSP00000349494 | Islet cell autoantigen 1; May play a role in neurotransmitter secretion. | Zinc finger protein 254; May be involved in transcriptional regulation. | 0.442 |
PKP2 | ZNF254 | ENSP00000070846 | ENSP00000349494 | Plakophilin-2; May play a role in junctional plaques. | Zinc finger protein 254; May be involved in transcriptional regulation. | 0.402 |
RPP38 | ZNF254 | ENSP00000478982 | ENSP00000349494 | Ribonuclease P protein subunit p38; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease complex, which cleaves pre- rRNA sequences. Belongs to the eukaryotic ribosomal protein eL8 family. | Zinc finger protein 254; May be involved in transcriptional regulation. | 0.432 |
TRIM28 | ZNF253 | ENSP00000253024 | ENSP00000468720 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 253; May function as a transcription factor. Seem to have a transcriptional repression activity; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.522 |
TRIM28 | ZNF254 | ENSP00000253024 | ENSP00000349494 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 254; May be involved in transcriptional regulation. | 0.600 |
TRIM28 | ZNF479 | ENSP00000253024 | ENSP00000333776 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 479; May be involved in transcriptional regulation. | 0.575 |
TRIM28 | ZNF675 | ENSP00000253024 | ENSP00000352836 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 675; May be involved in transcriptional regulation. May play a role during osteoclast differentiation by modulating TRAF6 signaling activity. | 0.580 |
TRIM28 | ZNF708 | ENSP00000253024 | ENSP00000349401 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 708; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.614 |
ZNF253 | CCNI2 | ENSP00000468720 | ENSP00000478257 | Zinc finger protein 253; May function as a transcription factor. Seem to have a transcriptional repression activity; Belongs to the krueppel C2H2-type zinc-finger protein family. | Cyclin-I2; Cyclin I family member 2. | 0.450 |
ZNF253 | TRIM28 | ENSP00000468720 | ENSP00000253024 | Zinc finger protein 253; May function as a transcription factor. Seem to have a transcriptional repression activity; Belongs to the krueppel C2H2-type zinc-finger protein family. | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | 0.522 |
ZNF253 | ZNF254 | ENSP00000468720 | ENSP00000349494 | Zinc finger protein 253; May function as a transcription factor. Seem to have a transcriptional repression activity; Belongs to the krueppel C2H2-type zinc-finger protein family. | Zinc finger protein 254; May be involved in transcriptional regulation. | 0.432 |
ZNF253 | ZNF675 | ENSP00000468720 | ENSP00000352836 | Zinc finger protein 253; May function as a transcription factor. Seem to have a transcriptional repression activity; Belongs to the krueppel C2H2-type zinc-finger protein family. | Zinc finger protein 675; May be involved in transcriptional regulation. May play a role during osteoclast differentiation by modulating TRAF6 signaling activity. | 0.484 |
ZNF253 | ZNF708 | ENSP00000468720 | ENSP00000349401 | Zinc finger protein 253; May function as a transcription factor. Seem to have a transcriptional repression activity; Belongs to the krueppel C2H2-type zinc-finger protein family. | Zinc finger protein 708; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.489 |
ZNF254 | CCNI2 | ENSP00000349494 | ENSP00000478257 | Zinc finger protein 254; May be involved in transcriptional regulation. | Cyclin-I2; Cyclin I family member 2. | 0.406 |
ZNF254 | FAM124B | ENSP00000349494 | ENSP00000386895 | Zinc finger protein 254; May be involved in transcriptional regulation. | Protein FAM124B; Family with sequence similarity 124 member B; Belongs to the FAM124 family. | 0.420 |
ZNF254 | ICA1 | ENSP00000349494 | ENSP00000403982 | Zinc finger protein 254; May be involved in transcriptional regulation. | Islet cell autoantigen 1; May play a role in neurotransmitter secretion. | 0.442 |
ZNF254 | PKP2 | ENSP00000349494 | ENSP00000070846 | Zinc finger protein 254; May be involved in transcriptional regulation. | Plakophilin-2; May play a role in junctional plaques. | 0.402 |