node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANKRA2 | ZNF337 | ENSP00000296785 | ENSP00000252979 | Ankyrin repeat family A protein 2; May regulate the interaction between the 3M complex and the histone deacetylases HDAC4 and HDAC5. May also regulate LRP2/megalin (By similarity). | Zinc finger protein 337; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.487 |
CCDC125 | ZNF337 | ENSP00000379754 | ENSP00000252979 | Coiled-coil domain-containing protein 125; May be involved in the regulation of cell migration. | Zinc finger protein 337; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.417 |
PCMTD2 | ZNF337 | ENSP00000307854 | ENSP00000252979 | protein-L-isoaspartate O-methyltransferase domain containing 2; Belongs to the methyltransferase superfamily. L- isoaspartyl/D-aspartyl protein methyltransferase family. | Zinc finger protein 337; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.489 |
TCTE1 | ZNF337 | ENSP00000360560 | ENSP00000252979 | Dynein regulatory complex subunit 5; Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. May play a role in the assembly of N-DRC. May be required for sperm motility. | Zinc finger protein 337; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.494 |
TRIM28 | ZNF133 | ENSP00000253024 | ENSP00000439427 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 133; May be involved in transcriptional regulation as a repressor. | 0.784 |
TRIM28 | ZNF227 | ENSP00000253024 | ENSP00000482749 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 227; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.585 |
TRIM28 | ZNF337 | ENSP00000253024 | ENSP00000252979 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 337; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.521 |
TRIM28 | ZSCAN32 | ENSP00000253024 | ENSP00000380061 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger and SCAN domain-containing protein 32; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.522 |
ZNF133 | TRIM28 | ENSP00000439427 | ENSP00000253024 | Zinc finger protein 133; May be involved in transcriptional regulation as a repressor. | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | 0.784 |
ZNF133 | ZNF337 | ENSP00000439427 | ENSP00000252979 | Zinc finger protein 133; May be involved in transcriptional regulation as a repressor. | Zinc finger protein 337; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.429 |
ZNF227 | TRIM28 | ENSP00000482749 | ENSP00000253024 | Zinc finger protein 227; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | 0.585 |
ZNF227 | ZNF337 | ENSP00000482749 | ENSP00000252979 | Zinc finger protein 227; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Zinc finger protein 337; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.414 |
ZNF337 | ANKRA2 | ENSP00000252979 | ENSP00000296785 | Zinc finger protein 337; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Ankyrin repeat family A protein 2; May regulate the interaction between the 3M complex and the histone deacetylases HDAC4 and HDAC5. May also regulate LRP2/megalin (By similarity). | 0.487 |
ZNF337 | CCDC125 | ENSP00000252979 | ENSP00000379754 | Zinc finger protein 337; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Coiled-coil domain-containing protein 125; May be involved in the regulation of cell migration. | 0.417 |
ZNF337 | PCMTD2 | ENSP00000252979 | ENSP00000307854 | Zinc finger protein 337; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | protein-L-isoaspartate O-methyltransferase domain containing 2; Belongs to the methyltransferase superfamily. L- isoaspartyl/D-aspartyl protein methyltransferase family. | 0.489 |
ZNF337 | TCTE1 | ENSP00000252979 | ENSP00000360560 | Zinc finger protein 337; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Dynein regulatory complex subunit 5; Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. May play a role in the assembly of N-DRC. May be required for sperm motility. | 0.494 |
ZNF337 | TRIM28 | ENSP00000252979 | ENSP00000253024 | Zinc finger protein 337; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | 0.521 |
ZNF337 | ZNF133 | ENSP00000252979 | ENSP00000439427 | Zinc finger protein 337; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Zinc finger protein 133; May be involved in transcriptional regulation as a repressor. | 0.429 |
ZNF337 | ZNF227 | ENSP00000252979 | ENSP00000482749 | Zinc finger protein 337; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Zinc finger protein 227; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.414 |
ZNF337 | ZSCAN26 | ENSP00000252979 | ENSP00000485228 | Zinc finger protein 337; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Zinc finger and SCAN domain-containing protein 26; May be involved in transcriptional regulation. | 0.457 |