node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARHGAP11B | ZNF394 | ENSP00000392760 | ENSP00000499131 | Rho GTPase-activating protein 11B; Hominin-specific protein that promotes development and evolutionary expansion of the brain neocortex. Able to promote amplification of basal progenitors in the subventricular zone, producing more neurons during fetal corticogenesis. Does not possess GTPase activator activity. | Zinc finger protein 394; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.466 |
ARHGAP11B-2 | ZNF394 | ENSP00000481934 | ENSP00000499131 | Rho GTPase activating protein 11B. | Zinc finger protein 394; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.466 |
HYPK | ZNF394 | ENSP00000384474 | ENSP00000499131 | Huntingtin-interacting protein K; Has a chaperone-like activity preventing polyglutamine (polyQ) aggregation of HTT. Protects against HTT polyQ-mediated apoptosis in Neuro2a neuronal cells. Regulator of the N-terminal acetyltransferase NAA10-NAA15 complex. Has been in one study shown to be required for optimal NAA10-NAA15 complex-mediated N-terminal acetylation. However, has been shown in another study to act in vitro as an inhibitor of NAA10-NAA15 complex-mediated N- terminal acetylation. | Zinc finger protein 394; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.462 |
LOC102724250 | ZNF394 | ENSP00000480818 | ENSP00000499131 | Neuroblastoma breakpoint family member 26. | Zinc finger protein 394; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.478 |
NBPF26 | ZNF394 | ENSP00000481542 | ENSP00000499131 | Neuroblastoma breakpoint family member 26; NBPF member 26. | Zinc finger protein 394; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.478 |
SCAND1 | ZNF394 | ENSP00000363103 | ENSP00000499131 | SCAN domain-containing protein 1; May regulate transcriptional activity. | Zinc finger protein 394; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.800 |
SCAND1 | ZNF397 | ENSP00000363103 | ENSP00000331577 | SCAN domain-containing protein 1; May regulate transcriptional activity. | Zinc finger protein 397; Isoform 3 acts as a DNA-dependent transcriptional repressor. | 0.837 |
SCAND1 | ZSCAN20 | ENSP00000363103 | ENSP00000355053 | SCAN domain-containing protein 1; May regulate transcriptional activity. | Zinc finger and SCAN domain-containing protein 20; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.813 |
SCAND1 | ZSCAN32 | ENSP00000363103 | ENSP00000380061 | SCAN domain-containing protein 1; May regulate transcriptional activity. | Zinc finger and SCAN domain-containing protein 32; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.834 |
TRIM28 | ZNF394 | ENSP00000253024 | ENSP00000499131 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 394; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.520 |
TRIM28 | ZSCAN32 | ENSP00000253024 | ENSP00000380061 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger and SCAN domain-containing protein 32; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.522 |
ZNF394 | ARHGAP11B | ENSP00000499131 | ENSP00000392760 | Zinc finger protein 394; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Rho GTPase-activating protein 11B; Hominin-specific protein that promotes development and evolutionary expansion of the brain neocortex. Able to promote amplification of basal progenitors in the subventricular zone, producing more neurons during fetal corticogenesis. Does not possess GTPase activator activity. | 0.466 |
ZNF394 | ARHGAP11B-2 | ENSP00000499131 | ENSP00000481934 | Zinc finger protein 394; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Rho GTPase activating protein 11B. | 0.466 |
ZNF394 | HYPK | ENSP00000499131 | ENSP00000384474 | Zinc finger protein 394; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Huntingtin-interacting protein K; Has a chaperone-like activity preventing polyglutamine (polyQ) aggregation of HTT. Protects against HTT polyQ-mediated apoptosis in Neuro2a neuronal cells. Regulator of the N-terminal acetyltransferase NAA10-NAA15 complex. Has been in one study shown to be required for optimal NAA10-NAA15 complex-mediated N-terminal acetylation. However, has been shown in another study to act in vitro as an inhibitor of NAA10-NAA15 complex-mediated N- terminal acetylation. | 0.462 |
ZNF394 | LOC102724250 | ENSP00000499131 | ENSP00000480818 | Zinc finger protein 394; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Neuroblastoma breakpoint family member 26. | 0.478 |
ZNF394 | NBPF26 | ENSP00000499131 | ENSP00000481542 | Zinc finger protein 394; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Neuroblastoma breakpoint family member 26; NBPF member 26. | 0.478 |
ZNF394 | SCAND1 | ENSP00000499131 | ENSP00000363103 | Zinc finger protein 394; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | SCAN domain-containing protein 1; May regulate transcriptional activity. | 0.800 |
ZNF394 | TRIM28 | ENSP00000499131 | ENSP00000253024 | Zinc finger protein 394; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | 0.520 |
ZNF394 | ZNF397 | ENSP00000499131 | ENSP00000331577 | Zinc finger protein 394; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Zinc finger protein 397; Isoform 3 acts as a DNA-dependent transcriptional repressor. | 0.799 |
ZNF394 | ZSCAN20 | ENSP00000499131 | ENSP00000355053 | Zinc finger protein 394; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Zinc finger and SCAN domain-containing protein 20; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.794 |