node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C16orf86 | ZNF613 | ENSP00000384117 | ENSP00000293471 | Uncharacterized protein C16orf86; Chromosome 16 open reading frame 86. | Zinc finger protein 613; May be involved in transcriptional regulation. | 0.479 |
CYSTM1 | ZNF613 | ENSP00000261811 | ENSP00000293471 | Cysteine-rich and transmembrane domain-containing protein 1; Cysteine rich transmembrane module containing 1. | Zinc finger protein 613; May be involved in transcriptional regulation. | 0.462 |
TRIM28 | ZNF17 | ENSP00000253024 | ENSP00000302455 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 17; May be involved in transcriptional regulation. | 0.547 |
TRIM28 | ZNF350 | ENSP00000253024 | ENSP00000243644 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 350; Transcriptional repressor. Binds to a specific sequence, 5'- GGGxxxCAGxxxTTT-3', within GADD45 intron 3. | 0.987 |
TRIM28 | ZNF613 | ENSP00000253024 | ENSP00000293471 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 613; May be involved in transcriptional regulation. | 0.522 |
TRIM28 | ZNF615 | ENSP00000253024 | ENSP00000471041 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 615; May be involved in transcriptional regulation. | 0.522 |
TRIM28 | ZNF790 | ENSP00000253024 | ENSP00000349161 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 790; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.567 |
TRIM28 | ZNF799 | ENSP00000253024 | ENSP00000411084 | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | Zinc finger protein 799; May be involved in transcriptional regulation. | 0.585 |
ZNF17 | TRIM28 | ENSP00000302455 | ENSP00000253024 | Zinc finger protein 17; May be involved in transcriptional regulation. | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | 0.547 |
ZNF17 | ZNF613 | ENSP00000302455 | ENSP00000293471 | Zinc finger protein 17; May be involved in transcriptional regulation. | Zinc finger protein 613; May be involved in transcriptional regulation. | 0.413 |
ZNF350 | TRIM28 | ENSP00000243644 | ENSP00000253024 | Zinc finger protein 350; Transcriptional repressor. Binds to a specific sequence, 5'- GGGxxxCAGxxxTTT-3', within GADD45 intron 3. | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | 0.987 |
ZNF350 | ZNF613 | ENSP00000243644 | ENSP00000293471 | Zinc finger protein 350; Transcriptional repressor. Binds to a specific sequence, 5'- GGGxxxCAGxxxTTT-3', within GADD45 intron 3. | Zinc finger protein 613; May be involved in transcriptional regulation. | 0.444 |
ZNF613 | C16orf86 | ENSP00000293471 | ENSP00000384117 | Zinc finger protein 613; May be involved in transcriptional regulation. | Uncharacterized protein C16orf86; Chromosome 16 open reading frame 86. | 0.479 |
ZNF613 | CYSTM1 | ENSP00000293471 | ENSP00000261811 | Zinc finger protein 613; May be involved in transcriptional regulation. | Cysteine-rich and transmembrane domain-containing protein 1; Cysteine rich transmembrane module containing 1. | 0.462 |
ZNF613 | TRIM28 | ENSP00000293471 | ENSP00000253024 | Zinc finger protein 613; May be involved in transcriptional regulation. | Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...] | 0.522 |
ZNF613 | ZNF17 | ENSP00000293471 | ENSP00000302455 | Zinc finger protein 613; May be involved in transcriptional regulation. | Zinc finger protein 17; May be involved in transcriptional regulation. | 0.413 |
ZNF613 | ZNF350 | ENSP00000293471 | ENSP00000243644 | Zinc finger protein 613; May be involved in transcriptional regulation. | Zinc finger protein 350; Transcriptional repressor. Binds to a specific sequence, 5'- GGGxxxCAGxxxTTT-3', within GADD45 intron 3. | 0.444 |
ZNF613 | ZNF615 | ENSP00000293471 | ENSP00000471041 | Zinc finger protein 613; May be involved in transcriptional regulation. | Zinc finger protein 615; May be involved in transcriptional regulation. | 0.498 |
ZNF613 | ZNF790 | ENSP00000293471 | ENSP00000349161 | Zinc finger protein 613; May be involved in transcriptional regulation. | Zinc finger protein 790; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.464 |
ZNF613 | ZNF799 | ENSP00000293471 | ENSP00000411084 | Zinc finger protein 613; May be involved in transcriptional regulation. | Zinc finger protein 799; May be involved in transcriptional regulation. | 0.780 |