node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GIMAP1-GIMAP5 | GIMAP5 | ENSP00000477920 | ENSP00000351473 | GIMAP1-GIMAP5 readthrough. | GTPase IMAP family member 5; Plays a role in T lymphocyte development and the optimal generation of CD4/CD8 double-positive thymocytes (By similarity). Inhibitor of GSK3A, possibly by sequestering GSK3A in cytoplasmic vesicles and impairing its translocation to the nucleus. Consequently, impairs GSK3A-dependent transcriptional program and regulation of the DNA damage response occurring during T cells proliferation. Required for the survival of peripheral T cells, natural killer (NK) and NK T-cell development and the maintenance of normal liver function (By similarity). May promote the [...] | 0.802 |
GIMAP1-GIMAP5 | GIMAP6 | ENSP00000477920 | ENSP00000479580 | GIMAP1-GIMAP5 readthrough. | GTPase, IMAP family member 6. | 0.749 |
GIMAP1-GIMAP5 | GIMAP7 | ENSP00000477920 | ENSP00000315474 | GIMAP1-GIMAP5 readthrough. | GTPase IMAP family member 7; The dimer has GTPase activity; the active site contains residues from both subunits. | 0.576 |
GIMAP1-GIMAP5 | GIMAP8 | ENSP00000477920 | ENSP00000305107 | GIMAP1-GIMAP5 readthrough. | GTPase IMAP family member 8; Exerts an anti-apoptotic effect in the immune system and is involved in responses to infections. | 0.612 |
GIMAP1-GIMAP5 | KRBA1 | ENSP00000477920 | ENSP00000418647 | GIMAP1-GIMAP5 readthrough. | Protein KRBA1; KRAB-A domain containing 1. | 0.463 |
GIMAP1-GIMAP5 | ZNF775 | ENSP00000477920 | ENSP00000330838 | GIMAP1-GIMAP5 readthrough. | Zinc finger protein 775; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.521 |
GIMAP2 | GIMAP6 | ENSP00000223293 | ENSP00000479580 | GTPase IMAP family member 2; The heterodimer formed by GIMAP2 and GIMAP7 has GTPase activity. In contrast, GIMAP2 has no GTPase activity by itself. | GTPase, IMAP family member 6. | 0.461 |
GIMAP2 | GIMAP7 | ENSP00000223293 | ENSP00000315474 | GTPase IMAP family member 2; The heterodimer formed by GIMAP2 and GIMAP7 has GTPase activity. In contrast, GIMAP2 has no GTPase activity by itself. | GTPase IMAP family member 7; The dimer has GTPase activity; the active site contains residues from both subunits. | 0.815 |
GIMAP2 | GIMAP8 | ENSP00000223293 | ENSP00000305107 | GTPase IMAP family member 2; The heterodimer formed by GIMAP2 and GIMAP7 has GTPase activity. In contrast, GIMAP2 has no GTPase activity by itself. | GTPase IMAP family member 8; Exerts an anti-apoptotic effect in the immune system and is involved in responses to infections. | 0.456 |
GIMAP2 | ZNF775 | ENSP00000223293 | ENSP00000330838 | GTPase IMAP family member 2; The heterodimer formed by GIMAP2 and GIMAP7 has GTPase activity. In contrast, GIMAP2 has no GTPase activity by itself. | Zinc finger protein 775; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.527 |
GIMAP5 | GIMAP1-GIMAP5 | ENSP00000351473 | ENSP00000477920 | GTPase IMAP family member 5; Plays a role in T lymphocyte development and the optimal generation of CD4/CD8 double-positive thymocytes (By similarity). Inhibitor of GSK3A, possibly by sequestering GSK3A in cytoplasmic vesicles and impairing its translocation to the nucleus. Consequently, impairs GSK3A-dependent transcriptional program and regulation of the DNA damage response occurring during T cells proliferation. Required for the survival of peripheral T cells, natural killer (NK) and NK T-cell development and the maintenance of normal liver function (By similarity). May promote the [...] | GIMAP1-GIMAP5 readthrough. | 0.802 |
GIMAP5 | GIMAP6 | ENSP00000351473 | ENSP00000479580 | GTPase IMAP family member 5; Plays a role in T lymphocyte development and the optimal generation of CD4/CD8 double-positive thymocytes (By similarity). Inhibitor of GSK3A, possibly by sequestering GSK3A in cytoplasmic vesicles and impairing its translocation to the nucleus. Consequently, impairs GSK3A-dependent transcriptional program and regulation of the DNA damage response occurring during T cells proliferation. Required for the survival of peripheral T cells, natural killer (NK) and NK T-cell development and the maintenance of normal liver function (By similarity). May promote the [...] | GTPase, IMAP family member 6. | 0.829 |
GIMAP5 | GIMAP7 | ENSP00000351473 | ENSP00000315474 | GTPase IMAP family member 5; Plays a role in T lymphocyte development and the optimal generation of CD4/CD8 double-positive thymocytes (By similarity). Inhibitor of GSK3A, possibly by sequestering GSK3A in cytoplasmic vesicles and impairing its translocation to the nucleus. Consequently, impairs GSK3A-dependent transcriptional program and regulation of the DNA damage response occurring during T cells proliferation. Required for the survival of peripheral T cells, natural killer (NK) and NK T-cell development and the maintenance of normal liver function (By similarity). May promote the [...] | GTPase IMAP family member 7; The dimer has GTPase activity; the active site contains residues from both subunits. | 0.830 |
GIMAP5 | GIMAP8 | ENSP00000351473 | ENSP00000305107 | GTPase IMAP family member 5; Plays a role in T lymphocyte development and the optimal generation of CD4/CD8 double-positive thymocytes (By similarity). Inhibitor of GSK3A, possibly by sequestering GSK3A in cytoplasmic vesicles and impairing its translocation to the nucleus. Consequently, impairs GSK3A-dependent transcriptional program and regulation of the DNA damage response occurring during T cells proliferation. Required for the survival of peripheral T cells, natural killer (NK) and NK T-cell development and the maintenance of normal liver function (By similarity). May promote the [...] | GTPase IMAP family member 8; Exerts an anti-apoptotic effect in the immune system and is involved in responses to infections. | 0.825 |
GIMAP5 | TMEM176B | ENSP00000351473 | ENSP00000410269 | GTPase IMAP family member 5; Plays a role in T lymphocyte development and the optimal generation of CD4/CD8 double-positive thymocytes (By similarity). Inhibitor of GSK3A, possibly by sequestering GSK3A in cytoplasmic vesicles and impairing its translocation to the nucleus. Consequently, impairs GSK3A-dependent transcriptional program and regulation of the DNA damage response occurring during T cells proliferation. Required for the survival of peripheral T cells, natural killer (NK) and NK T-cell development and the maintenance of normal liver function (By similarity). May promote the [...] | Transmembrane protein 176B; May play a role in the process of maturation of dendritic cells. Required for the development of cerebellar granule cells (By similarity). | 0.483 |
GIMAP5 | ZNF775 | ENSP00000351473 | ENSP00000330838 | GTPase IMAP family member 5; Plays a role in T lymphocyte development and the optimal generation of CD4/CD8 double-positive thymocytes (By similarity). Inhibitor of GSK3A, possibly by sequestering GSK3A in cytoplasmic vesicles and impairing its translocation to the nucleus. Consequently, impairs GSK3A-dependent transcriptional program and regulation of the DNA damage response occurring during T cells proliferation. Required for the survival of peripheral T cells, natural killer (NK) and NK T-cell development and the maintenance of normal liver function (By similarity). May promote the [...] | Zinc finger protein 775; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.471 |
GIMAP6 | GIMAP1-GIMAP5 | ENSP00000479580 | ENSP00000477920 | GTPase, IMAP family member 6. | GIMAP1-GIMAP5 readthrough. | 0.749 |
GIMAP6 | GIMAP2 | ENSP00000479580 | ENSP00000223293 | GTPase, IMAP family member 6. | GTPase IMAP family member 2; The heterodimer formed by GIMAP2 and GIMAP7 has GTPase activity. In contrast, GIMAP2 has no GTPase activity by itself. | 0.461 |
GIMAP6 | GIMAP5 | ENSP00000479580 | ENSP00000351473 | GTPase, IMAP family member 6. | GTPase IMAP family member 5; Plays a role in T lymphocyte development and the optimal generation of CD4/CD8 double-positive thymocytes (By similarity). Inhibitor of GSK3A, possibly by sequestering GSK3A in cytoplasmic vesicles and impairing its translocation to the nucleus. Consequently, impairs GSK3A-dependent transcriptional program and regulation of the DNA damage response occurring during T cells proliferation. Required for the survival of peripheral T cells, natural killer (NK) and NK T-cell development and the maintenance of normal liver function (By similarity). May promote the [...] | 0.829 |
GIMAP6 | GIMAP7 | ENSP00000479580 | ENSP00000315474 | GTPase, IMAP family member 6. | GTPase IMAP family member 7; The dimer has GTPase activity; the active site contains residues from both subunits. | 0.888 |