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The following proteins in
Homo sapiens
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101 query items
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1) '9606.ENSP00000252999':
LAMA5 - Laminin subunit alpha-5; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.
[a.k.a. AF443072, NM_005560.4, ENST00000471042.1]
2) '9606.ENSP00000264555':
PHRF1 - PHD and ring finger domains 1.
[a.k.a. NP_065952.2, PPP1R125, Q8IVY2]
3) '9606.ENSP00000292363':
RNF126 - E3 ubiquitin-protein ligase RNF126; E3 ubiquitin-protein ligase that mediates ubiquitination oF target proteins. Depending on the associated E2 ligase, mediates 'Lys-48'- and 'Lys-63'- linked polyubiquitination of substrates (By similarity). Part of a BAG6-dependent quality control process ensuring that proteins of the secretory pathway that are mislocalized to the cytosol are degraded by the proteasome. Probably acts by providing the ubiquitin ligase activity associated with the BAG6 complex and be responsible for ubiquitination of the hydrophobic mislocalized proteins and their targe [...]
[a.k.a. RNF126-204, ENST00000166144, FLJ20552]
4) '9606.ENSP00000312029':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
5) '9606.ENSP00000297508':
MICALL2 - MICAL-like protein 2; Effector of small Rab GTPases which is involved in junctional complexes assembly through the regulation of cell adhesion molecules transport to the plasma membrane and actin cytoskeleton reorganization. Regulates the endocytic recycling of occludins, claudins and E-cadherin to the plasma membrane and may thereby regulate the establishment of tight junctions and adherens junctions. In parallel, may regulate actin cytoskeleton reorganization directly through interaction with F-actin or indirectly through actinins and filamins. Most probably involved in the processes [...]
[a.k.a. ENST00000413446, 79778, Q8TEQ4]
6) '9606.ENSP00000387078':
WDSUB1 - WD repeat, sterile alpha motif and U-box domain containing 1.
[a.k.a. ENST00000409990.7, NM_001330274.2, 151525]
7) '9606.ENSP00000437616':
ZNF611 - Zinc finger protein 611; May be involved in transcriptional regulation.
[a.k.a. ZNF611-218, ENST00000597566.5, BC136343]
8) '9606.ENSP00000311122':
TMEM52 - Transmembrane protein 52.
[a.k.a. ENST00000378602, ENST00000416272, ENST00000602604.1]
9) '9606.ENSP00000378712':
IZUMO4 - Izumo sperm-egg fusion protein 4; IZUMO family member 4; Belongs to the Izumo family.
[a.k.a. Q1ZYL8, ENST00000590985, R-HSA-1474165]
10) '9606.ENSP00000470298':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
11) '9606.ENSP00000400500':
THAP5 - THAP domain-containing protein 5; Has sequence-specific DNA-binding activity and can function as transcriptional repressor (in vitro). May be a regulator of cell cycle: THAP5 overexpression in human cell lines causes cell cycle arrest at G2/M phase.
[a.k.a. NM_001130475.3, NP_001274528.1, Q7Z6K1]
12) '9606.ENSP00000262982':
CSE1L - Exportin-2; Export receptor for importin-alpha. Mediates importin-alpha re-export from the nucleus to the cytoplasm after import substrates (cargos) have been released into the nucleoplasm. In the nucleus binds cooperatively to importin-alpha and to the GTPase Ran in its active GTP-bound form. Docking of this trimeric complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, disassembling of the complex and hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause releas [...]
[a.k.a. ENST00000325964, AAC35297.1, Q9UP99]
13) '9606.ENSP00000337998':
NCKAP5L - Nck-associated protein 5-like; Regulates microtubule organization and stabilization. Promotes microtubule growth and bundling formation and stabilizes microtubules by increasing intense acetylation of microtubules. Both tubulin-binding and homodimer formation are required for NCKAP5L-mediated microtubule bundle formation.
[a.k.a. ENST00000480927.1, ENST00000301114, NP_001032895.2]
14) '9606.ENSP00000359664':
CTBS - Di-N-acetylchitobiase; Involved in the degradation of asparagine-linked glycoproteins. Hydrolyze of N-acetyl-beta-D-glucosamine (1-4)N- acetylglucosamine chitobiose core from the reducing end of the bond, it requires prior cleavage by glycosylasparaginase; Belongs to the glycosyl hydrolase 18 family.
[a.k.a. uc001dka.3, ENST00000370630.5, ENSP00000452177]
15) '9606.ENSP00000250340':
CLEC11A - C-type lectin domain family 11 member A; Promotes osteogenesis by stimulating the differentiation of mesenchymal progenitors into mature osteoblasts. Important for repair and maintenance of adult bone (By similarity).
[a.k.a. BC005810, P47, AAH05810.1]
16) '9606.ENSP00000466775':
APOC2 - Proapolipoprotein C-II; Component of chylomicrons, very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL) in plasma. Plays an important role in lipoprotein metabolism as an activator of lipoprotein lipase. Both proapolipoprotein C-II and apolipoprotein C-II can activate lipoprotein lipase. In normolipidemic individuals, it is mainly distributed in the HDL, whereas in hypertriglyceridemic individuals, predominantly found in the VLDL and LDL.
[a.k.a. ENST00000591597, R-HSA-388396, R-HSA-196854]
17) '9606.ENSP00000314004':
ANAPC2 - Anaphase-promoting complex subunit 2; Together with the RING-H2 protein ANAPC11, constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. The CDC20-APC/C complex positively re [...]
[a.k.a. 6OB1, R-HSA-2555396, R-HSA-174084]
18) '9606.ENSP00000313350':
RNASEH1 - Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. Plays a role in RNA polymerase II (RNAp II) transcription termination by degrading R-loop RNA-DNA hybrid formation at G-rich pause sites located downstream of the poly(A) site and behind the elongating RNAp II ; Belongs to the RNase H family.
[a.k.a. ENSP00000313350, HQ205127, AK075490]
19) '9606.ENSP00000345083':
MAP2K3 - Dual specificity mitogen-activated protein kinase kinase 3; Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38. Part of a signaling cascade that begins with the activation of the adrenergic receptor ADRA1B and leads to the activation of MAPK14. Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.
[a.k.a. MAPKK 3, ENST00000479129.5, ENSP00000434068]
20) '9606.ENSP00000384117':
C16orf86 - Uncharacterized protein C16orf86; Chromosome 16 open reading frame 86.
[a.k.a. AC010530, OTTHUMG00000150527, UPI0004620E72]
101 query items
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