searching ... STRING: functional protein association networks

Version:
12.0

The following proteins in Homo sapiens appear to match your input.
Please review the list, then click 'Continue' to proceed.

<- Back ⤓ Mapping Continue ->

102 query items

showing page 1 of 6 • first • previous • next • last

1) '9606.ENSP00000257515':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

2) '9606.ENSP00000373278':

ZCWPW2 - Zinc finger CW-type and PWWP domain containing 2. [a.k.a. UPI000198C983, XP_016861247, ENSP00000373278]

3) '9606.ENSP00000338785':

STARD13 - StAR-related lipid transfer protein 13; GTPase-activating protein for RhoA, and perhaps for Cdc42. May be involved in regulation of cytoskeletal reorganization, cell proliferation and cell motility. Acts a tumor suppressor in hepatocellular carcinoma cells. [a.k.a. BC046563, DLC2, ENST00000361430]

4) '9606.ENSP00000353013':

CLEC14A - C-type lectin domain containing 14A. [a.k.a. AAS77882.1, Q695G9, AY358395]

5) '9606.ENSP00000225831':

CCL2 - C-C motif chemokine 2; Acts as a ligand for C-C chemokine receptor CCR2. Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions. Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils. May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. [a.k.a. B2R4V3, CCDS11277.1, NM_002982.4]

6) '9606.ENSP00000219837':

KNOP1 - Lysine rich nucleolar protein 1. [a.k.a. C16orf88, ENSP00000219837, BC117562]

7) '9606.ENSP00000278601':

C11orf52 - Uncharacterized protein C11orf52; Chromosome 11 open reading frame 52. [a.k.a. ENST00000527286, Q96A22, NM_080659]

8) '9606.ENSP00000420321':

ROBO1 - Roundabout homolog 1; Receptor for SLIT1 and SLIT2 that mediates cellular responses to molecular guidance cues in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development. Interaction with the intracellular domain of FLRT3 mediates axon attraction towards cells expressing NTN1. In axon growth cones, the silencing of the attractive effect of NTN1 by SLIT2 may require the formation of a ROBO1-DCC complex (By similarity). Plays a role in the regulation of cell migration via its intera [...] [a.k.a. ROBO1-206, AC055731, 2V9Q]

9) '9606.ENSP00000349543':

PEX2 - Peroxisome biogenesis factor 2; Somewhat implicated in the biogenesis of peroxisomes; Belongs to the pex2/pex10/pex12 family. [a.k.a. ENST00000522527, NP_001165558.1, ENSP00000428590]

10) '9606.ENSP00000357494':

ROS1 - Proto-oncogene tyrosine-protein kinase ROS; Orphan receptor tyrosine kinase (RTK) that plays a role in epithelial cell differentiation and regionalization of the proximal epididymal epithelium. May activate several downstream signaling pathways related to cell differentiation, proliferation, growth and survival including the PI3 kinase-mTOR signaling pathway. Mediates the phosphorylation of PTPN11, an activator of this pathway. May also phosphorylate and activate the transcription factor STAT3 to control anchorage-independent cell growth. Mediates the phosphorylation and the activation [...] [a.k.a. XM_011536055, XP_006715611.1, 4UXL]

11) '9606.ENSP00000431443':

KRTAP5-9 - Keratin associated protein 5-9. [a.k.a. KRTAP5-1, R-HSA-6805567, AAH69531.1]

12) '9606.ENSP00000343129':

TRIM29 - Tripartite motif-containing protein 29; Plays a crucial role in the regulation of macrophage activation in response to viral or bacterial infections within the respiratory tract. Mechanistically, TRIM29 interacts with IKBKG/NEMO in the lysosome where it induces its 'Lys-48' ubiquitination and subsequent degradation. In turn, the expression of type I interferons and the production of proinflammatory cytokines are inhibited. Additionally, induces the 'Lys-48' ubiquitination of STING1 in a similar way, leading to its degradation. [a.k.a. XP_016872942, ENST00000529011.1, UPI0001F7887E]

13) '9606.ENSP00000294517':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

14) '9606.ENSP00000331626':

ZKSCAN2 - Zinc finger protein with KRAB and SCAN domains 2; May be involved in transcriptional regulation. [a.k.a. 342357, Q63HK3, ENST00000341751]

15) '9606.ENSP00000302234':

CCL11 - Eotaxin; In response to the presence of allergens, this protein directly promotes the accumulation of eosinophils, a prominent feature of allergic inflammatory reactions. Binds to CCR3. [a.k.a. eotaxin-1, R-HSA-162582, ENST00000305869]

16) '9606.ENSP00000377566':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

17) '9606.ENSP00000309142':

PDE12 - 2',5'-phosphodiesterase 12; Enzyme that cleaves 2',5'-phosphodiester bond linking adenosines of the 5'-triphosphorylated oligoadenylates, triphosphorylated oligoadenylates referred as 2-5A modulates the 2-5A system. Degrades triphosphorylated 2-5A to produce AMP and ATP. Also cleaves 3',5'-phosphodiester bond of oligoadenylates. Plays a role as a negative regulator of the 2-5A system that is one of the major pathways for antiviral and antitumor functions induced by interferons (IFNs). Suppression of this enzyme increases cellular 2-5A levels and decreases viral replication in cultured [...] [a.k.a. AB115695, Q6L8Q7, F6T1Q0]

18) '9606.ENSP00000304277':

TM4SF1 - Transmembrane 4 L six family member 1; Belongs to the L6 tetraspanin family. [a.k.a. UPI0000E5AA20, UPI000020A41D, ENST00000383054]

19) '9606.ENSP00000324648':

CYP2B6 - Cytochrome P450 2B6; A cytochrome P450 monooxygenase involved in the metabolism of endocannabinoids and steroids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH-- hemoprotein reductase). Catalyzes the epoxidation of double bonds of arachidonoylethanolamide (anandamide) to 8,9-, 11,12-, and 14,15- epoxyeicosatrienoic acid ethanolamides (EpETrE-EAs), potentially modulating endocannabinoid system signaling. Hydroxylates steroid hormon [...] [a.k.a. R-HSA-211999, CCDS12570, CPB6]

20) '9606.ENSP00000319179':

KDF1 - Keratinocyte differentiation factor 1; Plays a role in the regulation of the epidermis formation during early development. Required both as an inhibitor of basal cell proliferation and a promoter of differentiation of basal progenitor cell progeny (By similarity). [a.k.a. Keratinocyte differentiation factor 1, XP_005245792, 126695]

102 query items

showing page 1 of 6 • first • previous • next • last

<- Back ⤓ Mapping Continue ->

© STRING Consortium 2023

Credits

Access

Info

About