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The following proteins in
Homo sapiens
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101 query items
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1) '9606.ENSP00000274629':
KCNMB1 - Calcium-activated potassium channel subunit beta-1; Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Increases the apparent Ca(2+)/voltage sensitivity of the KCNMA1 channel. It also modifies KCNMA1 channel kinetics and alters its pharmacological properties. It slows down the activation and the deactivation kinetics of the channel. Acts as a negative regulator of smooth muscle contraction by enhancing the calcium sensitivity to KCNMA1. Its prese [...]
[a.k.a. 3779, k(VCA)beta-1, uc003maq.3]
2) '9606.ENSP00000462355':
H4C15 - H4 clustered histone 15.
[a.k.a. CH471087, AAH67496.1, R-HSA-5693565]
3) '9606.ENSP00000367034':
H4C3 - H4 clustered histone 3.
[a.k.a. CH471087, AAH67496.1, R-HSA-5693565]
4) '9606.ENSP00000482472':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
5) '9606.ENSP00000468057':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
6) '9606.ENSP00000440864':
NR4A1 - Nuclear receptor subfamily 4 group A member 1; Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3' (By similarity). May inhibit NF-kappa-B transactivation of IL2. Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation. Plays a role in the vascular response to injury (By similarity). ECO:0000250|UniProtKB:P12813.
[a.k.a. 2QW4, R-HSA-9006925, NR4A1-206]
7) '9606.ENSP00000222726':
HOXA5 - Homeobox protein Hox-A5; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Also binds to its own promoter. Binds specifically to the motif 5'-CYYNATTA[TG]Y-3'.
[a.k.a. 3202, ENSP00000222726, BC013682]
8) '9606.ENSP00000263080':
ASPA - Aspartoacylase; Catalyzes the deacetylation of N-acetylaspartic acid (NAA) to produce acetate and L-aspartate. NAA occurs in high concentration in brain and its hydrolysis NAA plays a significant part in the maintenance of intact white matter. In other tissues it act as a scavenger of NAA from body fluids.
[a.k.a. aspartoacylase, CCDS11028.1, ENSG00000108381]
9) '9606.ENSP00000323901':
FZD2 - Frizzled-2; Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to i [...]
[a.k.a. ENSG00000180340, BC113402, R-HSA-162582]
10) '9606.ENSP00000334472':
FOXE3 - Forkhead box protein E3; Transcription factor that controls lens epithelial cell growth through regulation of proliferation, apoptosis and cell cycle. During lens development, controls the ratio of the lens fiber cells to the cells of the anterior lens epithelium by regulating the rate of proliferation and differentiation (By similarity). Controls lens vesicle closure and subsequent separation of the lens vesicle from ectoderm (By similarity). Controls the expression of DNAJB1 in a pathway that is crucial for the development of the anterior segment of the eye.
[a.k.a. AL607122, AIY30327.1, ENST00000335071]
11) '9606.ENSP00000365908':
PRUNE2 - Protein prune homolog 2; May play an important role in regulating differentiation, survival and aggressiveness of the tumor cells.
[a.k.a. XM_005251750, ENST00000428286.5, ENSP00000393843]
12) '9606.ENSP00000462667':
H4C14 - H4 clustered histone 14.
[a.k.a. CH471087, AAH67496.1, R-HSA-5693565]
13) '9606.ENSP00000283249':
ITGB6 - Integrin beta-6; Integrin alpha-V:beta-6 (ITGAV:ITGB6) is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of integrin alpha-V/beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion. ITGAV:ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1. Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R-G- D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation. [...]
[a.k.a. R-HSA-2129379, hsa:3694, NP_001269319]
14) '9606.ENSP00000365663':
NPPA - Atrial natriuretic factor; Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.
[a.k.a. ANF, P01160, PND]
15) '9606.ENSP00000259324':
LRRC8A - Volume-regulated anion channel subunit LRRC8A; Essential component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and can also conduct organic osmolytes like taurine. Mediates efflux of amino acids, such as aspartate and glutamate, in response to osmotic stress. LRRC8A and LRRC8D are required for the uptake of the drug cisplatin. Required for in vivo channel activity, together with at l [...]
[a.k.a. ENST00000372600, LRRC8A-204, ENST00000259324]
16) '9606.ENSP00000347168':
H4C11 - H4 clustered histone 11.
[a.k.a. CH471087, AAH67496.1, R-HSA-5693565]
17) '9606.ENSP00000355895':
LYPLAL1 - Lysophospholipase-like protein 1; Has depalmitoylating activity toward KCNMA1. Does not exhibit phospholipase nor triacylglycerol lipase activity, able to hydrolyze only short chain substrates due to its shallow active site. Belongs to the AB hydrolase superfamily. AB hydrolase 2 family.
[a.k.a. HPA045806, NP_001287698.1, ENST00000469590]
18) '9606.ENSP00000279022':
MYL9 - Myosin regulatory light polypeptide 9; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion.
[a.k.a. Q9BQL9, MYL9-201, EAW76134.1]
19) '9606.ENSP00000307046':
SDC2 - Syndecan-2; Cell surface proteoglycan that bears heparan sulfate. Regulates dendritic arbor morphogenesis (By similarity).
[a.k.a. XP_011515514.1, R-HSA-388396, R-HSA-196854]
20) '9606.ENSP00000262113':
MYOM2 - Myomesin-2; Major component of the vertebrate myofibrillar M band. Binds myosin, titin, and light meromyosin. This binding is dose dependent.
[a.k.a. CAA48832.1, P54296, AAH52969.1]
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