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The following proteins in
Homo sapiens
appear to match your input.
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101 query items
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1) '9606.ENSP00000315702':
MOB4 - MOB-like protein phocein; May play a role in membrane trafficking, specifically in membrane budding reactions; Belongs to the MOB1/phocein family.
[a.k.a. CAG33652.1, AK292938, CGI-95]
2) '9606.ENSP00000310551':
LCLAT1 - Lysocardiolipin acyltransferase 1; Exhibits acyl-CoA:lysocardiolipin acyltransferase (ALCAT) activity; catalyzes the reacylation of lyso-cardiolipin to cardiolipin (CL), a key step in CL remodeling (By similarity). Recognizes both monolysocardiolipin and dilysocardiolipin as substrates with a preference for linoleoyl-CoA and oleoyl-CoA as acyl donors (By similarity). Also exhibits 1-acyl-sn-glycerol-3-phosphate acyltransferase activity (AGPAT) activity; converts 1-acyl-sn-glycerol- 3- phosphate (lysophosphatidic acid or LPA) into 1,2-diacyl-sn- glycerol-3- phosphate (phosphatidic acid [...]
[a.k.a. BAC04522.1, ENST00000540623, UPI0001B79872]
3) '9606.ENSP00000274026':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
4) '9606.ENSP00000263726':
LHX4 - LIM/homeobox protein Lhx4; May play a critical role in the development of respiratory control mechanisms and in the normal growth and maturation of the lung. Binds preferentially to methylated DNA.
[a.k.a. XM_011510108.2, Q8WWX2, LHX4-201]
5) '9606.ENSP00000264896':
SCARB2 - Lysosome membrane protein 2; Acts as a lysosomal receptor for glucosylceramidase (GBA) targeting.
[a.k.a. 4TVZ, ENST00000452464, Lysosome membrane protein 2]
6) '9606.ENSP00000482472':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
7) '9606.ENSP00000175091':
LAPTM4A - Lysosomal-associated transmembrane protein 4A; May function in the transport of nucleosides and/or nucleoside derivatives between the cytosol and the lumen of an intracellular membrane-bound compartment.
[a.k.a. BC000421, ENSG00000068697, CCDS1696.1]
8) '9606.ENSP00000386722':
FCHSD2 - F-BAR and double SH3 domains protein 2; Adapter protein that plays a role in endocytosis via clathrin-coated pits. Contributes to the internalization of cell surface receptors, such as integrin ITGB1 and transferrin receptor. Promotes endocytosis of EGFR in cancer cells, and thereby contributes to the down-regulation of EGFR signaling. Recruited to clathrin-coated pits during a mid-to- late stage of assembly, where it is required for normal progress from U-shaped intermediate stage pits to terminal, omega-shaped pits. Binds to membranes enriched in phosphatidylinositol 3,4-bisphosphate [...]
[a.k.a. XP_016874121.1, H0YG35, UPI000204AE53]
9) '9606.ENSP00000323805':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
10) '9606.ENSP00000483946':
PHF19 - PHD finger protein 19; Polycomb group (PcG) that specifically binds histone H3 trimethylated at 'Lys-36' (H3K36me3) and recruits the PRC2 complex. Probably involved in the transition from an active state to a repressed state in embryonic stem cells: acts by binding to H3K36me3, a mark for transcriptional activation, and recruiting H3K36me3 histone demethylases RIOX1 or KDM2B, leading to demethylation of H3K36 and recruitment of the PRC2 complex that mediates H3K27me3 methylation, followed by de novo silencing. Recruits the PRC2 complex to CpG islands and contributes to embryonic stem c [...]
[a.k.a. PHD finger protein 19, ENSP00000408479, UPI000006F815]
11) '9606.ENSP00000261854':
SPPL2A - Signal peptide peptidase-like 2A; Intramembrane-cleaving aspartic protease (I-CLiP) that cleaves type II membrane signal peptides in the hydrophobic plane of the membrane. Functions in FASLG, ITM2B and TNF processing. Catalyzes the intramembrane cleavage of the anchored fragment of shed TNF-alpha (TNF), which promotes the release of the intracellular domain (ICD) for signaling to the nucleus. Also responsible for the intramembrane cleavage of Fas antigen ligand FASLG, which promotes the release of the intracellular FasL domain (FasL ICD). May play a role in the regulation of innate and [...]
[a.k.a. R-HSA-162582, URS0000D6E055, ENST00000558414.1]
12) '9606.ENSP00000302543':
CXXC5 - CXXC-type zinc finger protein 5; May indirectly participate in activation of the NF-kappa-B and MAPK pathways. Acts as a mediator of BMP4-mediated modulation of canonical Wnt signaling activity in neural stem cells (By similarity). Required for DNA damage-induced ATM phosphorylation, p53 activation and cell cycle arrest. Involved in myelopoiesis. Transcription factor. Binds to the oxygen responsive element of COX4I2 and represses its transcription under hypoxia conditions (4% oxygen), as well as normoxia conditions (20% oxygen). May repress COX4I2 transactivation induced by CHCHD2 and [...]
[a.k.a. NM_001317200.2, CCDS43370.1, NP_001304137.1]
13) '9606.ENSP00000222584':
SP4 - Transcription factor Sp4; Binds to GT and GC boxes promoters elements. Probable transcriptional activator.
[a.k.a. ENST00000649633.1, MGC130009, ENST00000222584.7]
14) '9606.ENSP00000381666':
GXYLT1 - Glucoside xylosyltransferase 1; Glycosyltransferase which elongates the O-linked glucose attached to EGF-like repeats in the extracellular domain of Notch proteins by catalyzing the addition of xylose.
[a.k.a. NM_173601.2, glucoside xylosyltransferase 1, BC015597]
15) '9606.ENSP00000366953':
DCAF10 - DDB1- and CUL4-associated factor 10; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; Belongs to the WD repeat DCAF10 family.
[a.k.a. R-HSA-8951664, HGNC:23686, Q5QP82]
16) '9606.ENSP00000334538':
SREK1 - Splicing regulatory glutamine/lysine-rich protein 1; Participates in the regulation of alternative splicing by modulating the activity of other splice facors. Inhibits the splicing activity of SFRS1, SFRS2 and SFRS6. Augments the splicing activity of SFRS3 (By similarity).
[a.k.a. NM_001323527.2, SREK1-212, ENST00000524111]
17) '9606.ENSP00000366460':
PLXDC2 - Plexin domain-containing protein 2; May play a role in tumor angiogenesis. Belongs to the plexin family.
[a.k.a. 84898, NM_001282736.2, NM_032812.8]
18) '9606.ENSP00000437464':
FBXL17 - F-box/LRR-repeat protein 17; Substrate-recognition component of the SCF(FBXL17) E3 ubiquitin ligase complex, a key component of a quality control pathway required to ensure functional dimerization of BTB domain-containing proteins (dimerization quality control, DQC). FBXL17 specifically recognizes and binds a conserved degron of non-consecutive residues present at the interface of BTB dimers of aberrant composition: aberrant BTB dimer are then ubiquitinated by the SCF(FBXL17) complex and degraded by the proteaseome. The ability of the SCF(FBXL17) complex to eliminate compromised BTB di [...]
[a.k.a. FBXL17-204, EAW49061.1, F-box only protein 13]
19) '9606.ENSP00000313933':
BICRAL - BRD4-interacting chromatin-remodeling complex-associated protein-like; Component of SWI/SNF chromatin remodeling subcomplex GBAF that carries out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP- dependent manner.
[a.k.a. OTTHUMG00000014706, uc003osn.2, ENSP00000437976]
20) '9606.ENSP00000276201':
UPF3B - Regulator of nonsense transcripts 3B; Involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons by associating with the nuclear exon junction complex (EJC) and serving as link between the EJC core and NMD machinery. Recruits UPF2 at the cytoplasmic side of the nuclear envelope and the subsequent formation of an UPF1-UPF2-UPF3 surveillance complex (including UPF1 bound to release factors at the stalled ribosome) is believed to activate NMD. In cooperation with UPF2 stimulates both ATPase and RNA helicase activities of UPF1. Binds spliced mRNA upstream of exon-e [...]
[a.k.a. XP_016885227, UPI000006FF6A, ENST00000345865]
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