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The following proteins in
Homo sapiens
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101 query items
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1) '9606.ENSP00000323300':
SPAG5 - Sperm-associated antigen 5; Essential component of the mitotic spindle required for normal chromosome segregation and progression into anaphase. Required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture. In complex with SKAP, promotes stable microtubule- kinetochore attachments. May contribute to the regulation of separase activity. May regulate AURKA localization to mitotic spindle, but not to centrosomes and CCNB1 localization to both mitotic spindle and centrosomes. Involved in centriole duplication. Required for C [...]
[a.k.a. SPAG5-213, Deepest, ENST00000378976]
2) '9606.ENSP00000368808':
SMPX - Small muscular protein; Plays a role in the regulatory network through which muscle cells coordinate their structural and functional states during growth, adaptation, and repair.
[a.k.a. 23676, CCDS14200, NM_014332]
3) '9606.ENSP00000216330':
FKBP3 - Peptidyl-prolyl cis-trans isomerase FKBP3; FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. PPIases accelerate the folding of proteins.
[a.k.a. AAA58474.1, FK506-binding protein 3 (25kD), Q00688]
4) '9606.ENSP00000011473':
SYPL1 - Synaptophysin-like protein 1; Synaptophysin like 1; Belongs to the synaptophysin/synaptobrevin family.
[a.k.a. NM_182715.3, A0A0U1RQT9, NP_006745]
5) '9606.ENSP00000346127':
PLEKHB1 - Pleckstrin homology domain containing B1.
[a.k.a. PHRET1, Q9UI44, ENST00000227214.10]
6) '9606.ENSP00000312277':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
7) '9606.ENSP00000372023':
CHEK2 - Serine/threonine-protein kinase Chk2; Serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest, activation of DNA repair and apoptosis in response to the presence of DNA double-strand breaks. May also negatively regulate cell cycle progression during unperturbed cell cycles. Following activation, phosphorylates numerous effectors preferentially at the consensus sequence [L-X-R-X-X-S/T]. Regulates cell cycle checkpoint arrest through phosphorylation of CDC25A, CDC25B and CDC25C, inhibiting their activity. Inhibition of CDC25 phosphatase activity leads [...]
[a.k.a. 4A9S, 2XBJ, R-HSA-5693565]
8) '9606.ENSP00000417706':
DCUN1D2 - DCN1-like protein 2; Potently stimulates the neddylation of cullin components of SCF-type E3 ubiquitin ligase complexes from the NEDD8-conjugating E2 enzyme UBC12. Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.
[a.k.a. UPI0001B790CA, R-HSA-8951664, FLJ20092]
9) '9606.ENSP00000380494':
MYCL - Protein L-Myc; MYCL proto-oncogene, bHLH transcription factor.
[a.k.a. ENST00000450953, CAA30249.1, ENSP00000389358]
10) '9606.ENSP00000390849':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
11) '9606.ENSP00000216554':
EIF5 - Eukaryotic translation initiation factor 5; Catalyzes the hydrolysis of GTP bound to the 40S ribosomal initiation complex (40S.mRNA.Met-tRNA[F].eIF-2.GTP) with the subsequent joining of a 60S ribosomal subunit resulting in the release of eIF-2 and the guanine nucleotide. The subsequent joining of a 60S ribosomal subunit results in the formation of a functional 80S initiation complex (80S.mRNA.Met-tRNA[F]).
[a.k.a. R-HSA-72737, NP_001960.2, R-HSA-72706]
12) '9606.ENSP00000474823':
RNF103-CHMP3 - RNF103-CHMP3 readthrough.
[a.k.a. RNF103-CHMP3-201, ENSG00000249884, NM_001198954.1]
13) '9606.ENSP00000348056':
UBE2I - SUMO-conjugating enzyme UBC9; Accepts the ubiquitin-like proteins SUMO1, SUMO2, SUMO3, SUMO4 and SUMO1P1/SUMO5 from the UBLE1A-UBLE1B E1 complex and catalyzes their covalent attachment to other proteins with the help of an E3 ligase such as RANBP2, CBX4 and ZNF451. Can catalyze the formation of poly-SUMO chains. Necessary for sumoylation of FOXL2 and KAT5. Essential for nuclear architecture and chromosome segregation. Sumoylates p53/TP53 at 'Lys-386'. Mediates sumoylation of ERCC6 which is essential for its transcription-coupled nucleotide excision repair activity. Belongs to the ubiqu [...]
[a.k.a. ENST00000566159.1, ENST00000567074, NP_919235]
14) '9606.ENSP00000229583':
ADTRP - Androgen-dependent TFPI-regulating protein; Hydrolyzes bioactive fatty-acid esters of hydroxy-fatty acids (FAHFAs), but not other major classes of lipids. Show a preference for FAHFAs with branching distal from the carboxylate head group of the lipids. Regulates the expression and the cell-associated anticoagulant activity of the inhibitor TFPI in endothelial cells (in vitro). Belongs to the AIG1 family.
[a.k.a. CH471087, ENST00000514824, ADTRP-208]
15) '9606.ENSP00000453858':
PAK6 - Serine/threonine-protein kinase PAK 6; Serine/threonine protein kinase that plays a role in the regulation of gene transcription. The kinase activity is induced by various effectors including AR or MAP2K6/MAPKK6. Phosphorylates the DNA-binding domain of androgen receptor/AR and thereby inhibits AR- mediated transcription. Inhibits also ESR1-mediated transcription. May play a role in cytoskeleton regulation by interacting with IQGAP1. May protect cells from apoptosis through phosphorylation of BAD.
[a.k.a. BUB1B-PAK6, ENSP00000452737, G5E9R2]
16) '9606.ENSP00000420919':
TMEM150C - Transmembrane protein 150C; Component of a mechanosensitive cation channel. Confers mechanically activated (MA) currents with slow inactivation kinetics. May contribute to proprioception; Belongs to the DRAM/TMEM150 family.
[a.k.a. AAI47028.1, ENST00000508701.5, ENST00000449862]
17) '9606.ENSP00000384770':
PSG4 - Pregnancy specific beta-1-glycoprotein 4.
[a.k.a. URS00008BCD71, URS00008B5191, R-HSA-202733]
18) '9606.ENSP00000360242':
XIAP - E3 ubiquitin-protein ligase XIAP; Multi-functional protein which regulates not only caspases and apoptosis, but also modulates inflammatory signaling and immunity, copper homeostasis, mitogenic kinase signaling, cell proliferation, as well as cell invasion and metastasis. Acts as a direct caspase inhibitor. Directly bind to the active site pocket of CASP3 and CASP7 and obstructs substrate entry. Inactivates CASP9 by keeping it in a monomeric, inactive state. Acts as an E3 ubiquitin-protein ligase regulating NF-kappa-B signaling and the target proteins for its E3 ubiquitin-protein ligas [...]
[a.k.a. 1I51, 5OQW, R-HSA-9006925]
19) '9606.ENSP00000452793':
GDPGP1 - GDP-D-glucose phosphorylase 1; Specific and highly efficient GDP-D-glucose phosphorylase regulating the levels of GDP-D-glucose in cells.
[a.k.a. URS0000EA5F76, A0A024RC68, NP_001309740.1]
20) '9606.ENSP00000370593':
PTPRD - Receptor-type tyrosine-protein phosphatase delta; Can bidirectionally induce pre- and post-synaptic differentiation of neurons by mediating interaction with IL1RAP and IL1RAPL1 trans-synaptically. Involved in pre-synaptic differentiation through interaction with SLITRK2; Belongs to the protein-tyrosine phosphatase family. Receptor class 2A subfamily.
[a.k.a. 2DLH, XP_016870449.1, AL583805]
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