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The following proteins in
Homo sapiens
appear to match your input.
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101 query items
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1) '9606.ENSP00000325074':
PPP2R2A - Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
[a.k.a. XP_011542867, XM_011544565.1, R-HSA-2555396]
2) '9606.ENSP00000305613':
CPLX1 - Complexin-1; Positively regulates a late step in exocytosis of various cytoplasmic vesicles, such as synaptic vesicles and other secretory vesicles. Organizes the SNAREs into a cross-linked zigzag topology that, when interposed between the vesicle and plasma membranes, is incompatible with fusion, thereby preventing SNAREs from releasing neurotransmitters until an action potential arrives at the synapse. Also involved in glucose-induced secretion of insulin by pancreatic beta-cells. Essential for motor behavior. Belongs to the complexin/synaphin family.
[a.k.a. R-HSA-210500, R-HSA-112315, EIEE63]
3) '9606.ENSP00000413520':
HID1 - Protein HID1; May play an important role in the development of cancers in a broad range of tissues.
[a.k.a. HID1-204, XR_001752478, UPI00000746AC]
4) '9606.ENSP00000338272':
HEY1 - Hairy/enhancer-of-split related with YRPW motif protein 1; Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3'. Downstream effector of Notch signaling required for cardiovascular development. Specifically required for the Notch-induced endocardial epithelial to mesenchymal transition, which is itself criticial for cardiac valve and septum development. May be required in conjunction with HEY2 to specify arterial cell fate or identity. Promotes maintenance of neuronal precursor cells and glial versus neuronal fate specification. Represses tra [...]
[a.k.a. bHLHb31, NP_001269780.1, R-HSA-2122947]
5) '9606.ENSP00000342832':
YPEL1 - Protein yippee-like 1; May play a role in epithelioid conversion of fibroblasts; Belongs to the yippee family.
[a.k.a. ENST00000339468.7, O60688, ENSG00000100027]
6) '9606.ENSP00000355778':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
7) '9606.ENSP00000441927':
SESN3 - Sestrin-3; May function as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway. May also regulate the insulin-receptor signaling pathway through activation of TORC2 (By similarity). This metabolic regulator may also play a role in protection against oxidative and genotoxic stresses (By similarity).
[a.k.a. BAH13685.1, SEST3, 143686]
8) '9606.ENSP00000458977':
DPEP2 - Dipeptidase 2; Probable metalloprotease which hydrolyzes leukotriene D4 (LTD4) into leukotriene E4 (LTE4).
[a.k.a. ENSP00000459375, XP_011521570, Q8TC95]
9) '9606.ENSP00000319531':
GCSH - Glycine cleavage system H protein, mitochondrial; The glycine cleavage system catalyzes the degradation of glycine. The H protein (GCSH) shuttles the methylamine group of glycine from the P protein (GLDC) to the T protein (GCST). Belongs to the GcvH family.
[a.k.a. XP_016878626.1, H3BQ30, ENST00000569885.6]
10) '9606.ENSP00000368931':
CCDC112 - Coiled-coil domain containing 112.
[a.k.a. XP_005271965, CCDS34213.1, CC112_HUMAN]
11) '9606.ENSP00000355493':
ADSS2 - Adenylosuccinate synthetase isozyme 2; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP. Belongs to the adenylosuccinate synthetase family.
[a.k.a. NP_001352002.1, ADSS, ENSP00000355493]
12) '9606.ENSP00000477352':
SCOC - Short coiled-coil protein; Positive regulator of amino acid starvation-induced autophagy; Belongs to the SCOC family.
[a.k.a. NP_001147162.1, E9PB65, Q9UIL1]
13) '9606.ENSP00000365730':
STK24 - Serine/threonine-protein kinase 24 12 kDa subunit; Serine/threonine-protein kinase that acts on both serine and threonine residues and promotes apoptosis in response to stress stimuli and caspase activation. Mediates oxidative-stress-induced cell death by modulating phosphorylation of JNK1-JNK2 (MAPK8 and MAPK9), p38 (MAPK11, MAPK12, MAPK13 and MAPK14) during oxidative stress. Plays a role in a staurosporine-induced caspase-independent apoptotic pathway by regulating the nuclear translocation of AIFM1 and ENDOG and the DNase activity associated with ENDOG. Phosphorylates STK38L on 'Thr [...]
[a.k.a. 4U8Z, 4QO9, 3A7G]
14) '9606.ENSP00000228820':
PARP11 - Protein mono-ADP-ribosyltransferase PARP11; Mono-ADP-ribosyltransferase that mediates mono-ADP- ribosylation of target proteins. Plays a role in nuclear envelope stability and nuclear remodeling during spermiogenesis (By similarity).
[a.k.a. XM_011520973.2, ENST00000476985, ENST00000427057]
15) '9606.ENSP00000305133':
SOCS5 - Suppressor of cytokine signaling 5; SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. May be a substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5- SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Inhibits for instance EGF signaling by mediating the degradation of the EGF receptor/EGFR. Involved in the regulation of T- helper cell differentiation by inhibiting of the IL4 signaling pathway which promotes diff [...]
[a.k.a. R-HSA-8951664, hsa:9655, ENST00000568862.1]
16) '9606.ENSP00000238738':
RHOQ - Rho-related GTP-binding protein RhoQ; Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. May play a role in CFTR trafficking to the plasma membrane. Causes the formation of thin, actin-rich surface projections called filopodia.
[a.k.a. ENSP00000393140, TC10, R-HSA-162582]
17) '9606.ENSP00000348381':
ADD3 - Gamma-adducin; Membrane-cytoskeleton-associated protein that promotes the assembly of the spectrin-actin network. Plays a role in actin filament capping. Binds to calmodulin. Belongs to the aldolase class II family. Adducin subfamily.
[a.k.a. XP_024303562.1, XP_024303565.1, ENST00000488837.1]
18) '9606.ENSP00000344635':
CCNG1 - Cyclin-G1; May play a role in growth regulation. Is associated with G2/M phase arrest in response to DNA damage. May be an intermediate by which p53 mediates its role as an inhibitor of cellular proliferation (By similarity).
[a.k.a. E7ERZ1, ENST00000509143.1, Cyclin-G]
19) '9606.ENSP00000283179':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
20) '9606.ENSP00000273261':
LRIG1 - Leucine-rich repeats and immunoglobulin-like domains protein 1; Acts as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation.
[a.k.a. LRIG1-207, R-HSA-6807004, R-HSA-6806834]
101 query items
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