searching ... STRING: functional protein association networks

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The following proteins in Homo sapiens appear to match your input.
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101 query items

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1) '9606.ENSP00000345681':

GATA2 - Endothelial transcription factor GATA-2; Transcriptional activator which regulates endothelin-1 gene expression in endothelial cells. Binds to the consensus sequence 5'- AGATAG-3'. [a.k.a. ENSP00000313010, AC080005, Q96BH8]

2) '9606.ENSP00000264313':

SLAIN2 - SLAIN motif-containing protein 2; Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization. Promotes cytoplasmic microtubule nucleation and elongation. Required for normal structure of the microtubule cytoskeleton during interphase. [a.k.a. BC031691, ENST00000506375, NM_020846]

3) '9606.ENSP00000356630':

HECA - Headcase protein homolog; May play an important role in some human cancers. May be part of the regulatory mechanism in the development of epithelial tube networks such as the circulatory system and lungs. [a.k.a. NP_057301, ENST00000230165, OMIM:607977]

4) '9606.ENSP00000370256':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

5) '9606.ENSP00000392028':

CHD7 - Chromodomain-helicase-DNA-binding protein 7; Probable transcription regulator. Maybe involved in the in 45S precursor rRNA production. [a.k.a. ENST00000532149, CHD7-210, D0VBA5]

6) '9606.ENSP00000380692':

KDM7A - Lysine-specific demethylase 7A; Histone demethylase required for brain development. Specifically demethylates dimethylated 'Lys-9' and 'Lys-27' (H3K9me2 and H3K27me2, respectively) of histone H3 and monomethylated histone H4 'Lys-20' residue (H4K20Me1), thereby playing a central role in histone code. Specifically binds trimethylated 'Lys-4' of histone H3 (H3K4me3), affecting histone demethylase specificity: in presence of H3K4me3, it has no demethylase activity toward H3K9me2, while it has high activity toward H3K27me2. Demethylates H3K9me2 in absence of H3K4me3. Has activity toward H4 [...] [a.k.a. NM_030647.2, XP_011514889.1, KDM7A-203]

7) '9606.ENSP00000371634':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

8) '9606.ENSP00000294016':

ADCY9 - Adenylate cyclase type 9; Adenylyl cyclase that catalyzes the formation of the signaling molecule cAMP in response to activation of G protein-coupled receptors. Contributes to signaling cascades activated by CRH (corticotropin-releasing factor), corticosteroids and beta-adrenergic receptors. [a.k.a. I3L342, AC9, R-HSA-388396]

9) '9606.ENSP00000350789':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

10) '9606.ENSP00000316426':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

11) '9606.ENSP00000354869':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

12) '9606.ENSP00000304985':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

13) '9606.ENSP00000303997':

GTPBP2 - GTP binding protein 2. [a.k.a. ENST00000307114.11, Q9NX60, NM_019096.4]

14) '9606.ENSP00000442046':

TMTC1 - Protein O-mannosyl-transferase TMTC1; Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl- transferases dedicated primarily to the cadherin superfamily, each member seems to have a distinct role in decorating the cadherin domains with O-linked mannose glycans at specific regions. Also acts as O- mannosyl-transferase on other proteins such as PDIA3. [a.k.a. HPA016720, TMTC1-204, uc001rjb.4]

15) '9606.ENSP00000265563':

PRKAR2A - cAMP-dependent protein kinase type II-alpha regulatory subunit; Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells. Type II regulatory chains mediate membrane association by binding to anchoring proteins, including the MAP2 kinase. [a.k.a. R-HSA-388396, R-HSA-9006925, R-HSA-163615]

16) '9606.ENSP00000362299':

ENG - Endoglin; Vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis. Required for normal structure and integrity of adult vasculature. Regulates the migration of vascular endothelial cells. Required for normal extraembryonic angiogenesis and for embryonic heart development (By similarity). May regulate endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis (By similarity). May play a critical role in the binding of endothelial cells to integrins [...] [a.k.a. CHEMBL3712885, EAW87703.1, LRG_589t2]

17) '9606.ENSP00000322242':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

18) '9606.ENSP00000185206':

CLIC5 - Chloride intracellular channel protein 5; Required for normal hearing. It is necessary for the formation of stereocilia in the inner ear and normal development of the organ of Corti (By similarity). Can insert into membranes and form poorly selective ion channels that may also transport chloride ions. May play a role in the regulation of transepithelial ion absorption and secretion. Is required for the development and/or maintenance of the proper glomerular endothelial cell and podocyte architecture. Plays a role in formation of the lens suture in the eye, which is important for normal [...] [a.k.a. BAC11432.1, Q9NZA1, CLIC5-208]

19) '9606.ENSP00000335091':

ZNRF1 - E3 ubiquitin-protein ligase ZNRF1; E3 ubiquitin-protein ligase that mediates the ubiquitination of AKT1 and GLUL, thereby playing a role in neuron cells differentiation. Plays a role in the establishment and maintenance of neuronal transmission and plasticity. Regulates Schwann cells differentiation by mediating ubiquitination of GLUL. Promotes neurodegeneration by mediating 'Lys-48'-linked polyubiquitination and subsequent degradation of AKT1 in axons: degradation of AKT1 prevents AKT1-mediated phosphorylation of GSK3B, leading to GSK3B activation and phosphorylation of DPYSL2/CRMP2 f [...] [a.k.a. URS0000EAFF38, Q8ND25, ZNRF1-203]

20) '9606.ENSP00000252996':

TAF4 - Transcription initiation factor TFIID subunit 4; Part of the TFIID complex, a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. Potentiates transcriptional activation by the AF-2S of the retinoic acid, vitamin D3 and thyroid hormone. [a.k.a. R-HSA-162587, R-HSA-73776, TAFII130]

101 query items

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