searching ... STRING: functional protein association networks

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The following proteins in Homo sapiens appear to match your input.
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101 query items

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1) '9606.ENSP00000355385':

R3HDM4 - R3H domain containing 4. [a.k.a. ENSP00000466823, Q96D70, ENST00000626716.1]

2) '9606.ENSP00000337816':

MMP25 - Matrix metalloproteinase-25; May activate progelatinase A. [a.k.a. EAW85415.1, NM_022468.5, XP_024306159.1]

3) '9606.ENSP00000305059':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

4) '9606.ENSP00000241600':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

5) '9606.ENSP00000218056':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

6) '9606.ENSP00000300305':

RUNX1 - Runt-related transcription factor 1; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX. The heterodimers bind to the core site of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T [...] [a.k.a. R-HSA-8939247, ENST00000479325, X90976]

7) '9606.ENSP00000355060':

ARHGEF10L - Rho guanine nucleotide exchange factor 10-like protein; Acts as guanine nucleotide exchange factor (GEF) for RHOA, RHOB and RHOC. [a.k.a. R-HSA-388396, ENSP00000326952, HPA026426]

8) '9606.ENSP00000345083':

MAP2K3 - Dual specificity mitogen-activated protein kinase kinase 3; Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38. Part of a signaling cascade that begins with the activation of the adrenergic receptor ADRA1B and leads to the activation of MAPK14. Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily. [a.k.a. MAPKK 3, ENST00000479129.5, ENSP00000434068]

9) '9606.ENSP00000253458':

GSE1 - Genetic suppressor element 1; Gse1 coiled-coil protein. [a.k.a. UPI0007E52C8F, XP_005255917.3, H7C3B5]

10) '9606.ENSP00000261797':

NDST1 - Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1; Essential bifunctional enzyme that catalyzes both the N- deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Plays a role in determining the extent and pattern of sulfation of heparan sulfate. Compared to other NDST enzymes, its presence is absolutely required. Participates in biosynthesis of heparan sulfate [...] [a.k.a. NM_001543, XP_016864917.1, Glucosaminyl N-deacetylase/N-sulfotransferase 1]

11) '9606.ENSP00000356022':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

12) '9606.ENSP00000263208':

HIRA - Protein HIRA; Cooperates with ASF1A to promote replication-independent chromatin assembly. Required for the periodic repression of histone gene transcription during the cell cycle. Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit. [a.k.a. R-HSA-2559584, H7C2A7, X81844]

13) '9606.ENSP00000419692':

RXRA - Retinoic acid receptor RXR-alpha; Receptor for retinoic acid that acts as a transcription factor. Forms homo- or heterodimers with retinoic acid receptors (RARs) and binds to target response elements in response to their ligands, all-trans or 9-cis retinoic acid, to regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5 to regulate transcription. The high affinity ligand for retinoid X receptors (RXRs) is 9-cis retinoic acid. In the absence of ligand, th [...] [a.k.a. 1XVP, 1K74, URS00008C3308]

14) '9606.ENSP00000250144':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

15) '9606.ENSP00000406674':

MOGAT1 - 2-acylglycerol O-acyltransferase 1; Catalyzes the formation of diacylglycerol from 2- monoacylglycerol and fatty acyl-CoA. Probably not involved in absorption of dietary fat in the small intestine (By similarity). Belongs to the diacylglycerol acyltransferase family. [a.k.a. ENSG00000124003, HGNC:18210, DGAT2L]

16) '9606.ENSP00000363257':

ZDHHC18 - Palmitoyltransferase ZDHHC18; Has palmitoyltransferase activity towards HRAS and LCK. [a.k.a. CCDS30650, DHHC18, AAH66776.1]

17) '9606.ENSP00000412886':

CAMTA2 - Calmodulin-binding transcription activator 2; Transcription activator. May act as tumor suppressor. Belongs to the CAMTA family. [a.k.a. ENST00000575192, UPI0000140EBA, URS0000D6E83C]

18) '9606.ENSP00000303211':

ACHE - Acetylcholinesterase; Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. Role in neuronal apoptosis. Belongs to the type-B carboxylesterase/lipase family. [a.k.a. 6CQV, AAK21003.1, UPI0003F48229]

19) '9606.ENSP00000219782':

MAZ - Myc-associated zinc finger protein; May function as a transcription factor with dual roles in transcription initiation and termination. Binds to two sites, ME1a1 and ME1a2, within the MYC promoter having greater affinity for the former. Also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors. Regulates inflammation-induced expression of serum amyloid A proteins. [a.k.a. HPA065930, I3L4D3, UPI0000EE81B1]

20) '9606.ENSP00000338487':

MGAT4B - Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase B; Glycosyltransferase that participates in the transfer of N- acetylglucosamine (GlcNAc) to the core mannose residues of N-linked glycans. Catalyzes the formation of the GlcNAcbeta1-4 branch on the GlcNAcbeta1-2Manalpha1-3 arm of the core structure of N-linked glycans. Essential for the production of tri- and tetra-antennary N-linked sugar chains. Has lower affinities for donors or acceptors than MGAT4A, suggesting that, under physiological conditions, it is not the main contributor in N-glycan biosynthesis. [a.k.a. Q9UQ53, E5RFS3, ENST00000518778]

101 query items

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