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The following proteins in
Homo sapiens
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101 query items
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1) '9606.ENSP00000360918':
CH25H - Cholesterol 25-hydroxylase; Catalyzes the formation of 25-hydroxycholesterol from cholesterol, leading to repress cholesterol biosynthetic enzymes. Plays a key role in cell positioning and movement in lymphoid tissues: 25-hydroxycholesterol is an intermediate in biosynthesis of 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC), an oxysterol that acts as a ligand for the G protein-coupled receptor GPR183/EBI2, a chemotactic receptor for a number of lymphoid cells. May play an important role in regulating lipid metabolism by synthesizing a corepressor that blocks sterol regulatory element [...]
[a.k.a. ENSG00000138135, NM_003956, R-HSA-556833]
2) '9606.ENSP00000324277':
APOLD1 - Apolipoprotein L domain-containing protein 1; May be involved in angiogenesis. May play a role in activity- dependent changes of brain vasculature. May affect blood-brain permeability.
[a.k.a. Vascular early response gene protein, NP_110444.3, NP_001123887.1]
3) '9606.ENSP00000262817':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
4) '9606.ENSP00000284322':
ABI3BP - Target of Nesh-SH3; ABI family member 3 binding protein.
[a.k.a. XM_005247300.3, XP_011510955, XP_011510959]
5) '9606.ENSP00000270620':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
6) '9606.ENSP00000316861':
GPM6B - Neuronal membrane glycoprotein M6-b; May be involved in neural development. Involved in regulation of osteoblast function and bone formation. Involved in matrix vesicle release by osteoblasts; this function seems to involve maintenance of the actin cytoskeleton. May be involved in cellular trafficking of SERT and thereby in regulation of serotonin uptake.
[a.k.a. GPM6B-204, C9JZE8, ENST00000472735]
7) '9606.ENSP00000374328':
FAXC - Failed axon connections homolog; May play a role in axonal development.
[a.k.a. Failed axon connections homolog, BAG53301.1, ENSG00000146267]
8) '9606.ENSP00000360076':
SGIP1 - SH3-containing GRB2-like protein 3-interacting protein 1; May function in clathrin-mediated endocytosis. Has both a membrane binding/tubulating activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. Has a preference for membranes enriched in phosphatidylserine and phosphoinositides and is required for the endocytosis of the transferrin receptor. May also bind tubulin. May play a role in the regulation of energy homeostasis.
[a.k.a. XP_016858013.1, XP_006711029.1, ENST00000435165]
9) '9606.ENSP00000310593':
MAP9 - Microtubule-associated protein 9; Involved in organization of the bipolar mitotic spindle. Required for bipolar spindle assembly, mitosis progression and cytokinesis. May act by stabilizing interphase microtubules.
[a.k.a. uc003ios.4, MAP9-205, Q68DU1]
10) '9606.ENSP00000377823':
NDRG4 - Protein NDRG4; Contributes to the maintenance of intracerebral BDNF levels within the normal range, which is necessary for the preservation of spatial learning and the resistance to neuronal cell death caused by ischemic stress (By similarity). May enhance growth factor-induced ERK1 and ERK2 phosphorylation, including that induced by PDGF and FGF. May attenuate NGF-promoted ELK1 phosphorylation in a microtubule-dependent manner.
[a.k.a. ENSP00000454274, ENST00000565430, EAW82979.1]
11) '9606.ENSP00000358162':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
12) '9606.ENSP00000359603':
COL24A1 - Collagen alpha-1(XXIV) chain; May participate in regulating type I collagen fibrillogenesis at specific anatomical locations during fetal development. Belongs to the fibrillar collagen family.
[a.k.a. NP_690850, E9PNK8, NR_146344.1]
13) '9606.ENSP00000353129':
KCTD8 - BTB/POZ domain-containing protein KCTD8; Auxiliary subunit of GABA-B receptors that determine the pharmacology and kinetics of the receptor response. Increases agonist potency and markedly alter the G-protein signaling of the receptors by accelerating onset and promoting desensitization (By similarity).
[a.k.a. 386617, XM_011513690, KCTD8-201]
14) '9606.ENSP00000337088':
MEN1 - Menin; Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of cell-proliferation, possibly regulating SMAD3 transcriptional activity. Represses JUND-mediated transcriptional activation on AP1 sites, as well as that mediated by NFKB subunit RELA. Positively regulates HOXC8 and HOXC6 gene expression. May be involved in normal hematopoiesis through the [...]
[a.k.a. R-HSA-170834, NM_130800.2, 6E1A]
15) '9606.ENSP00000297142':
NEUROD6 - Neurogenic differentiation factor 6; Activates E box-dependent transcription in collaboration with TCF3/E47. May be a trans-acting factor involved in the development and maintenance of the mammalian nervous system. Transactivates the promoter of its own gene (By similarity).
[a.k.a. Math-2, BAF82308.1, ENST00000297142]
16) '9606.ENSP00000326581':
PEG3 - Paternally-expressed gene 3 protein; Induces apoptosis in cooperation with SIAH1A. Acts as a mediator between p53/TP53 and BAX in a neuronal death pathway that is activated by DNA damage. Acts synergistically with TRAF2 and inhibits TNF induced apoptosis through activation of NF-kappa-B (By similarity). Possesses a tumor suppressing activity in glioma cells; Belongs to the krueppel C2H2-type zinc-finger protein family.
[a.k.a. PEG3-204, UPI000E6EAA3D, AF208970]
17) '9606.ENSP00000340944':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
18) '9606.ENSP00000254976':
SNAP25 - Synaptosomal-associated protein 25; t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 in pancreatic beta cells. Belongs to the SNAP-25 family.
[a.k.a. XP_016883510.1, bA416N4.2, dJ1068F16.2]
19) '9606.ENSP00000295718':
PTPRN - Receptor-type tyrosine-protein phosphatase-like N; Plays a role in vesicle-mediated secretory processes. Required for normal accumulation of secretory vesicles in hippocampus, pituitary and pancreatic islets (By similarity). Required for the accumulation of normal levels of insulin- containing vesicles and preventing their degradation. Plays a role in insulin secretion in response to glucose stimuli. Required for normal accumulation of the neurotransmitters norepinephrine, dopamine and serotonin in the brain (By similarity). In females, but not in males, required for normal accumulatio [...]
[a.k.a. URS0000D6DDDD, ENSP00000386638, UPI00018819A7]
20) '9606.ENSP00000360608':
GRIN1 - Glutamate receptor ionotropic, NMDA 1; Component of NMDA receptor complexes that function as heterotetrameric, ligand-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Channel activation requires binding of the neurotransmitter glutamate to the epsilon subunit, glycine binding to the zeta subunit, plus membrane depolarization to eliminate channel inhibition by Mg(2+). Sensitivity to glutamate and channel kinetics depend on the subunit composition.
[a.k.a. OMIM:138249, NMDZ1_HUMAN, NM_000832.7]
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