searching ... STRING: functional protein association networks

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The following proteins in Homo sapiens appear to match your input.
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101 query items

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1) '9606.ENSP00000385721':

GGT2 - Inactive glutathione hydrolase 2; Isoform 1, isoform 2 and isoform 3 lack catalytic activity due to its inability to undergo the autocatalytic cleavage needed to produce a mature, enzymatically active heterodimer. [a.k.a. XP_006724455, ENSP00000249062, XM_017029181.2]

2) '9606.ENSP00000287748':

LYZL4 - Lysozyme-like protein 4; May be involved in fertilization (By similarity). Has no detectable bacteriolytic and lysozyme activities in vitro (By similarity); Belongs to the glycosyl hydrolase 22 family. [a.k.a. ENSG00000157093, XM_017005706.1, ENST00000470991]

3) '9606.ENSP00000302936':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

4) '9606.ENSP00000298542':

FRMD7 - FERM domain-containing protein 7; Plays a role in neurite development, may be through the activation of the GTPase RAC1. Plays a role in the control of eye movement and gaze stability. [a.k.a. UPI00001C2063, NYS1, HPA000886]

5) '9606.ENSP00000343234':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

6) '9606.ENSP00000370555':

GYG2 - Glycogenin-2; Self-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase. Belongs to the glycosyltransferase 8 family. Glycogenin subfamily. [a.k.a. CCDS55365, Glycogenin-2, AAB84375.1]

7) '9606.ENSP00000367817':

PODXL - Podocalyxin; Involved in the regulation of both adhesion and cell morphology and cancer progression. Functions as an anti-adhesive molecule that maintains an open filtration pathway between neighboring foot processes in the podocyte by charge repulsion. Acts as a pro- adhesive molecule, enhancing the adherence of cells to immobilized ligands, increasing the rate of migration and cell-cell contacts in an integrin-dependent manner. Induces the formation of apical actin- dependent microvilli. Involved in the formation of a preapical plasma membrane subdomain to set up initial epithelial p [...] [a.k.a. NP_005388.2, O00592, ENSP00000440518]

8) '9606.ENSP00000387694':

SLC12A5 - Solute carrier family 12 member 5; Mediates electroneutral potassium-chloride cotransport in mature neurons and is required for neuronal Cl(-) homeostasis. As major extruder of intracellular chloride, it establishes the low neuronal Cl(-) levels required for chloride influx after binding of GABA-A and glycine to their receptors, with subsequent hyperpolarization and neuronal inhibition (By similarity). Involved in the regulation of dendritic spine formation and maturation. [a.k.a. K-Cl cotransporter 2, V9GYL3, ENSP00000484585]

9) '9606.ENSP00000278765':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

10) '9606.ENSP00000296695':

SPINK1 - Serine protease inhibitor Kazal-type 1; Serine protease inhibitor which exhibits anti-trypsin activity. In the pancreas, protects against trypsin- catalyzed premature activation of zymogens (By similarity). [a.k.a. Spink3, SPINK1-203, NP_003113.2]

11) '9606.ENSP00000340505':

SENP8 - Sentrin-specific protease 8; Protease that catalyzes two essential functions in the NEDD8 pathway: processing of full-length NEDD8 to its mature form and deconjugation of NEDD8 from targeted proteins such as cullins or p53. [a.k.a. NP_001159812.1, UPI0000135852, R-HSA-8951664]

12) '9606.ENSP00000308576':

RHOD - Rho-related GTP-binding protein RhoD; Involved in endosome dynamics. May coordinate membrane transport with the function of the cytoskeleton. Involved in the internalization and trafficking of activated tyrosine kinase receptors such as PDGFRB. Participates in the reorganization of actin cytoskeleton; the function seems to involve WHAMM and includes regulation of filopodia formation and actin filament bundling. Can modulate the effect of DAPK3 in reorganization of actin cytoskeleton and focal adhesion dissolution; Belongs to the small GTPase superfamily. Rho family. [a.k.a. 29984, 2J1L, R-HSA-162582]

13) '9606.ENSP00000298050':

DEUP1 - Deuterosome assembly protein 1; Key structural component of the deuterosome, a structure that promotes de novo centriole amplification in multiciliated cells. Deuterosome-mediated centriole amplification occurs in terminally differentiated multiciliated cells and can generate more than 100 centrioles. Probably sufficient for the specification and formation of the deuterosome inner core. Interacts with CEP152 and recruits PLK4 to activate centriole biogenesis (By similarity); Belongs to the CEP63 family. [a.k.a. ENST00000298050, NP_857596, NP_857596.2]

14) '9606.ENSP00000366326':

NEBL - Nebulette; Binds to actin and plays an important role in the assembly of the Z-disk. May functionally link sarcomeric actin to the desmin intermediate filaments in the heart muscle sarcomeres. Isoform 2 might play a role in the assembly of focal adhesion. [a.k.a. XM_005252343, 10529, NP_006384.1]

15) '9606.ENSP00000023897':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

16) '9606.ENSP00000377527':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

17) '9606.ENSP00000362743':

C2orf72 - Uncharacterized protein C2orf72; Chromosome 2 open reading frame 72. [a.k.a. ENST00000373640.4, HPA044962, uc002vrl.5]

18) '9606.ENSP00000386878':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

19) '9606.ENSP00000336984':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

20) '9606.ENSP00000322175':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

101 query items

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