searching ... STRING: functional protein association networks

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The following proteins in Homo sapiens appear to match your input.
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101 query items

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1) '9606.ENSP00000444788':

TDO2 - Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. [a.k.a. 6A4I, TDO, ENSG00000151790]

2) '9606.ENSP00000217964':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

3) '9606.ENSP00000356630':

HECA - Headcase protein homolog; May play an important role in some human cancers. May be part of the regulatory mechanism in the development of epithelial tube networks such as the circulatory system and lungs. [a.k.a. NP_057301, ENST00000230165, OMIM:607977]

4) '9606.ENSP00000357012':

CD244 - Natural killer cell receptor 2B4; Heterophilic receptor of the signaling lymphocytic activation molecule (SLAM) family; its ligand is CD48. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. Acts as activating natural killer (NK) cell receptor. Activating functi [...] [a.k.a. AAK00233.1, ENSP00000357012, R-HSA-202733]

5) '9606.ENSP00000374558':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

6) '9606.ENSP00000294702':

GFI1 - Zinc finger protein Gfi-1; Transcription repressor essential for hematopoiesis. Functions in a cell-context and development-specific manner. Binds to 5'-TAAATCAC[AT]GCA-3' in the promoter region of a large number of genes. Component of several complexes, including the EHMT2-GFI1-HDAC1, AJUBA-GFI1-HDAC1 and RCOR-GFI-KDM1A-HDAC complexes, that suppress, via histone deacetylase (HDAC) recruitment, a number of genes implicated in multilineage blood cell development. Regulates neutrophil differentiation, promotes proliferation of lymphoid cells, and is required for granulocyte development. [...] [a.k.a. ENST00000358323, uc001dou.5, ENST00000312884]

7) '9606.ENSP00000327832':

ATAT1 - Alpha-tubulin N-acetyltransferase 1; Specifically acetylates 'Lys-40' in alpha-tubulin on the lumenal side of microtubules. Promotes microtubule destabilization and accelerates microtubule dynamics; this activity may be independent of acetylation activity. Acetylates alpha-tubulin with a slow enzymatic rate, due to a catalytic site that is not optimized for acetyl transfer. Enters the microtubule through each end and diffuses quickly throughout the lumen of microtubules. Acetylates only long/old microtubules because of its slow acetylation rate since it does not have time to act on dyn [...] [a.k.a. OTTHUMG00000031219, AL845353, alpha-TAT]

8) '9606.ENSP00000274507':

LECT2 - Leukocyte cell-derived chemotaxin-2; Has a neutrophil chemotactic activity. Also a positive regulator of chondrocyte proliferation. Does not show metalloendopeptidase activity. Belongs to the LECT2/MIM-1 family. [a.k.a. 3950, LECT2-205, OTTHUMG00000129146]

9) '9606.ENSP00000310219':

HSPA6 - Heat shock 70 kDa protein 6; Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis and ADP [...] [a.k.a. NM_002155.4, uc001gaq.4, R-HSA-3371571]

10) '9606.ENSP00000264497':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

11) '9606.ENSP00000401597':

DTHD1 - Death domain containing 1. [a.k.a. NX_Q6ZMT9, XP_016863682, hsa:401124]

12) '9606.ENSP00000227348':

CRTAM - Cytotoxic and regulatory T-cell molecule; Interaction with CADM1 promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo; Belongs to the nectin family. [a.k.a. BC070266, NP_062550, NM_001304782.2]

13) '9606.ENSP00000263100':

A1BG - Alpha-1B-glycoprotein; alpha-1-B glycoprotein. [a.k.a. GAB, ENSP00000263100, AAL07469.1]

14) '9606.ENSP00000358016':

SCML4 - Sex comb on midleg-like protein 4; Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development (By similarity). [a.k.a. SCML4-202, XM_011535706.1, ENST00000479803]

15) '9606.ENSP00000263126':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

16) '9606.ENSP00000421725':

GC - Vitamin D-binding protein; Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation. Belongs to the ALB/AFP/VDB family. [a.k.a. NP_001191235, GC-206, ENST00000504199]

17) '9606.ENSP00000282091':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

18) '9606.ENSP00000417289':

CTAGE8 - CTAGE family member 8. [a.k.a. AK292236, CTGE8_HUMAN, HPA000922]

19) '9606.ENSP00000263851':

IL7 - Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. [a.k.a. 3574, ENST00000639719.1, 3DI3]

20) '9606.ENSP00000339634':

KIR2DL4 - Killer cell immunoglobulin-like receptor 2DL4; Receptor for non-classical major histocompatibility class Ib HLA-G molecules. Recognizes HLA-G in complex with B2M/beta-2 microglobulin and a nonamer self-peptide (peptide-bound HLA-G-B2M). In decidual NK cells, binds peptide-bound HLA-G-B2M complex and triggers NK cell senescence-associated secretory phenotype as a molecular switch to promote vascular remodeling and fetal growth in early pregnancy. May play a role in balancing tolerance and antiviral-immunity at maternal-fetal interface by keeping in check the effector functions of NK, CD [...] [a.k.a. ENST00000486965.6, KIR2DL4-205, G9P]

101 query items

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