searching ... STRING: functional protein association networks

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The following proteins in Homo sapiens appear to match your input.
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101 query items

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1) '9606.ENSP00000453089':

H0YL77_HUMAN - Uncharacterized protein. [a.k.a. uc058zwv.1, ENST00000558325, ENSP00000453089]

2) '9606.ENSP00000440689':

CYP2E1 - Cytochrome P450 2E1; A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be involved in the oxidative metabolism of xenobiotics (Probable). [a.k.a. R-HSA-211999, NP_000764, CYP2E1-202]

3) '9606.ENSP00000477037':

V9GYS4_HUMAN - Uncharacterized protein. [a.k.a. V9GYS4, AL163636.3, Novel protein, ANG-RNASE4 readthrough]

4) '9606.ENSP00000428056':

PIK3R1 - Phosphatidylinositol 3-kinase regulatory subunit alpha; Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB. Likewise, plays a role in ITGB2 signaling. Modulates the cellular response to ER stress by promoting nuclear translocation [...] [a.k.a. R-HSA-388396, R-HSA-912526, R-HSA-1643713]

5) '9606.ENSP00000308535':

GOLT1A - Vesicle transport protein GOT1A; May be involved in fusion of ER-derived transport vesicles with the Golgi complex; Belongs to the GOT1 family. [a.k.a. BAC85915.1, ENST00000367193, GOT1]

6) '9606.ENSP00000297524':

SLC7A13 - Solute carrier family 7 member 13; Mediates the transport L-aspartate and L-glutamate in a sodium-independent manner; Belongs to the amino acid-polyamine-organocation (APC) superfamily. [a.k.a. NM_138817.2, XAT2, NP_620172]

7) '9606.ENSP00000320401':

UGT2B17 - UDP-glucuronosyltransferase 2B17; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. The major substrates of this isozyme are eugenol > 4- methylumbelliferone > dihydrotestosterone (DHT) > androstane-3- alpha,17-beta-diol (3-alpha-diol) > testosterone > androsterone (ADT). [a.k.a. R-HSA-156588, Glucuronosyltransferase, UDP-glucuronosyltransferase 2B17]

8) '9606.ENSP00000336762':

ANG - Angiogenin; Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus. Stimulates ribosomal RNA synthesis including that containing the initiation site sequences of 45S rRNA. Cleaves tRNA within anticodon loops to produce tRNA-derived stress-induced fragments (tiRNAs) which inhibit protein synthesis and triggers the assembly of stress granules (SGs). Angiogenin induces vascularization of normal and malignant tissues. Angiogenic activity is regulated by interaction with RNH1 in vivo. [a.k.a. BAG36701.1, P03950, ANGI_HUMAN]

9) '9606.ENSP00000199936':

HSD17B2 - Estradiol 17-beta-dehydrogenase 2; Capable of catalyzing the interconversion of testosterone and androstenedione, as well as estradiol and estrone. Also has 20-alpha- HSD activity. Uses NADH while EDH17B3 uses NADPH; Belongs to the short-chain dehydrogenases/reductases (SDR) family. [a.k.a. P37059, AAH59170.1, H3BRZ6]

10) '9606.ENSP00000381605':

PCDHGA8 - Protocadherin gamma-A8; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain. [a.k.a. protocadherin gamma subfamily A, 8, uc003lkb.5, HPA010580]

11) '9606.ENSP00000379367':

LYRM1 - LYR motif-containing protein 1; May promote cell proliferation and inhibition of apoptosis of preadipocytes; Belongs to the complex I LYR family. [a.k.a. ENST00000568663, NP_001356570, XM_017023482.1]

12) '9606.ENSP00000371331':