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The following proteins in
Homo sapiens
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102 query items
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1) '9606.ENSP00000454913':
ARMH2 - Armadillo-like helical domain-containing protein 2; Armadillo like helical domain containing 2.
[a.k.a. ENST00000623403, ENSP00000454913, NP_001269421]
2) '9606.ENSP00000364858':
CARD16 - Caspase recruitment domain-containing protein 16; Caspase inhibitor. Acts as a regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro-inflammatory cytokine response. Also able to inhibit CASP1-mediated neuronal cell death, TNF- alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of cas [...]
[a.k.a. caspase recruitment domain family member 16, hsa:114769, ENSG00000204397]
3) '9606.ENSP00000410481':
LTB - Lymphotoxin-beta; Cytokine that binds to LTBR/TNFRSF3. May play a specific role in immune response regulation. Provides the membrane anchor for the attachment of the heterotrimeric complex to the cell surface. Isoform 2 is probably non-functional.
[a.k.a. L11015, NM_009588, NP_033666]
4) '9606.ENSP00000360215':
ZBP1 - Z-DNA-binding protein 1; Participates in the detection by the host's innate immune system of DNA from viral, bacterial or even host origin. Plays a role in host defense against tumors and pathogens. Acts as a cytoplasmic DNA sensor which, when activated, induces the recruitment of TBK1 and IRF3 to its C-terminal region and activates the downstream interferon regulatory factor (IRF) and NF-kappa B transcription factors, leading to type-I interferon production. ZBP1-induced NF-kappaB activation probably involves the recruitment of the RHIM containing kinases RIPK1 and RIPK3 (By similarity).
[a.k.a. NM_001323966.2, NP_001310895.1, DLM1]
5) '9606.ENSP00000240618':
KLRK1 - NKG2-D type II integral membrane protein; Functions as an activating and costimulatory receptor involved in immunosurveillance upon binding to various cellular stress- inducible ligands displayed at the surface of autologous tumor cells and virus-infected cells. Provides both stimulatory and costimulatory innate immune responses on activated killer (NK) cells, leading to cytotoxic activity. Acts as a costimulatory receptor for T-cell receptor (TCR) in CD8(+) T-cell-mediated adaptive immune responses by amplifying T-cell activation. Stimulates perforin-mediated elimination of ligand-exp [...]
[a.k.a. KLRC4-KLRK1, KLRK1-202, ENST00000540267]
6) '9606.ENSP00000325708':
CD37 - Leukocyte antigen CD37; CD37 molecule.
[a.k.a. ENST00000597033, TSPAN26, NP_001035120.1]
7) '9606.ENSP00000311300':
CTSW - Cathepsin W; May have a specific function in the mechanism or regulation of T-cell cytolytic activity; Belongs to the peptidase C1 family.
[a.k.a. NP_001326, UPI0001F78115, Lymphopain]
8) '9606.ENSP00000219919':
AQP9 - Aquaporin-9; Forms a water channel with a broad specificity. Also permeable glycerol and urea. Mediates passage of a wide variety of small, non-charged solutes including carbamides, polyols, purines, and pyrimidines; Belongs to the MIP/aquaporin (TC 1.A.8) family.
[a.k.a. NM_001320635.2, AC066616, OTTHUMG00000132631]
9) '9606.ENSP00000266659':
GLIPR1 - Glioma pathogenesis-related protein 1; GLI pathogenesis related 1; Belongs to the CRISP family.
[a.k.a. XP_011536077, ENST00000456650, Protein RTVP-1]
10) '9606.ENSP00000348635':
JAML - Junctional adhesion molecule-like; Transmembrane protein of the plasma membrane of leukocytes that control their migration and activation through interaction with CXADR, a plasma membrane receptor found on adjacent epithelial and endothelial cells. The interaction between both receptors mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, JAML induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferat [...]
[a.k.a. CCDS8391, R-HSA-202733, JAML-209]
11) '9606.ENSP00000349143':
BTN2A2 - Butyrophilin subfamily 2 member A2; Inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion. Belongs to the immunoglobulin superfamily. BTN/MOG family.
[a.k.a. CH471087, XM_005248797.3, EAW55564.1]
12) '9606.ENSP00000322276':
VNN2 - Vascular non-inflammatory molecule 2; Amidohydrolase that hydrolyzes specifically one of the carboamide linkages in D-pantetheine thus recycling pantothenic acid (vitamin B5) and releasing cysteamine. Involved in the thymus homing of bone marrow cells. May regulate beta-2 integrin-mediated cell adhesion, migration and motility of neutrophil; Belongs to the carbon-nitrogen hydrolase superfamily. BTD/VNN family.
[a.k.a. ENST00000530536, BAF84814.1, R-HSA-196854]
13) '9606.ENSP00000364992':
LY6G6F - Lymphocyte antigen 6 complex locus protein G6f; May play a role in the downstream signal transduction pathways involving GRB2 and GRB7.
[a.k.a. NM_001003693.3, lymphocyte antigen 6 complex, locus G6F, AAF35181.1]
14) '9606.ENSP00000262709':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
15) '9606.ENSP00000357152':
CD1C - T-cell surface glycoprotein CD1c; Antigen-presenting protein that binds self and non-self lipid and glycolipid antigens and presents them to T-cell receptors on natural killer T-cells.
[a.k.a. CD1C-202, 911, CAG33361.1]
16) '9606.ENSP00000295756':
TRAT1 - T-cell receptor-associated transmembrane adapter 1; Stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells.
[a.k.a. R-HSA-9006925, TRIM, R-HSA-162582]
17) '9606.ENSP00000305529':
SIRPG - Signal-regulatory protein gamma; Probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T-cells by CD47 on antigen-presenting cells results in enhanced antigen- specific T-cell proliferation and costimulates T-cell activation.
[a.k.a. CCDS13020.2, R-HSA-202733, AB042624]
18) '9606.ENSP00000257497':
- - Sorry, STRING found no proteins by this name in Homo sapiens - -
19) '9606.ENSP00000300182':
MS4A6E - Membrane-spanning 4-domains subfamily A member 6E; May be involved in signal transduction as a component of a multimeric receptor complex.
[a.k.a. Q3MIL2, NP_640342.1, CCDS7984.1]
20) '9606.ENSP00000265404':
STAP1 - Signal-transducing adaptor protein 1; In BCR signaling, appears to function as a docking protein acting downstream of TEC and participates in a positive feedback loop by increasing the activity of TEC.
[a.k.a. Q9ULZ2, NP_001304698, AB023483]
102 query items
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