searching ... STRING: functional protein association networks

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The following proteins in Homo sapiens appear to match your input.
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101 query items

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1) '9606.ENSP00000467176':

TNNT1 - Troponin T, slow skeletal muscle; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. [a.k.a. ENST00000593194.5, HPA058448, ENST00000587758.5]

2) '9606.ENSP00000300896':

USP32 - Ubiquitin specific peptidase 32; Belongs to the peptidase C19 family. [a.k.a. XP_011523673.1, UPI0002841186, BC054344]

3) '9606.ENSP00000470734':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

4) '9606.ENSP00000357012':

CD244 - Natural killer cell receptor 2B4; Heterophilic receptor of the signaling lymphocytic activation molecule (SLAM) family; its ligand is CD48. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response. Activities are controlled by presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2. Acts as activating natural killer (NK) cell receptor. Activating functi [...] [a.k.a. AAK00233.1, ENSP00000357012, R-HSA-202733]

5) '9606.ENSP00000271324':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

6) '9606.ENSP00000286639':

BATF - Basic leucine zipper transcriptional factor ATF-like; AP-1 family transcription factor that controls the differentiation of lineage-specific cells in the immune system: specifically mediates the differentiation of T-helper 17 cells (Th17), follicular T-helper cells (TfH), CD8(+) dendritic cells and class- switch recombination (CSR) in B-cells. Acts via the formation of a heterodimer with JUNB that recognizes and binds DNA sequence 5'- TGA[CG]TCA-3'. The BATF-JUNB heterodimer also forms a complex with IRF4 (or IRF8) in immune cells, leading to recognition of AICE sequence (5'- TGAnTCA/G [...] [a.k.a. AF016898, BC032294, NP_006390]

7) '9606.ENSP00000330442':

PLB1 - Phospholipase B1, membrane-associated; Membrane-associated phospholipase. Exhibits a calcium- independent broad substrate specificity including phospholipase A2/lysophospholipase activity. Preferential hydrolysis at the sn-2 position of diacylphospholipids and diacyglycerol, whereas it shows no positional specificity toward triacylglycerol. Exhibits also esterase activity toward p-nitrophenyl. May act on the brush border membrane to facilitate the absorption of digested lipids (By similarity). [a.k.a. R-HSA-388396, R-HSA-196854, XP_011530895.1]

8) '9606.ENSP00000309509':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

9) '9606.ENSP00000316772':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

10) '9606.ENSP00000310219':

HSPA6 - Heat shock 70 kDa protein 6; Molecular chaperone implicated in a wide variety of cellular processes, including protection of the proteome from stress, folding and transport of newly synthesized polypeptides, activation of proteolysis of misfolded proteins and the formation and dissociation of protein complexes. Plays a pivotal role in the protein quality control system, ensuring the correct folding of proteins, the re-folding of misfolded proteins and controlling the targeting of proteins for subsequent degradation. This is achieved through cycles of ATP binding, ATP hydrolysis and ADP [...] [a.k.a. NM_002155.4, uc001gaq.4, R-HSA-3371571]

11) '9606.ENSP00000300659':

NFATC3 - Nuclear factor of activated T-cells, cytoplasmic 3; Acts as a regulator of transcriptional activation. Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2. Along with NFATC4, involved in embryonic heart development (By similarity). [a.k.a. NM_004555.3, ENST00000549350, R-HSA-983705]

12) '9606.ENSP00000265968':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

13) '9606.ENSP00000358931':

TKTL1 - Transketolase-like protein 1; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate; Belongs to the transketolase family. [a.k.a. Z49258, TKT2, CH471172]

14) '9606.ENSP00000295971':

RBM47 - RNA binding motif protein 47; Belongs to the RRM RBM47 family. [a.k.a. XP_016863796, ENST00000513473, XM_017008310.2]

15) '9606.ENSP00000341031':

TPRG1 - Tumor protein p63 regulated 1; Belongs to the TPRG1 family. [a.k.a. XP_024309243, XP_016861752.1, URS00008B4D7E]

16) '9606.ENSP00000297436':

DEFA6 - Defensin-6; Has very low antimicrobial activity against Gram-negative and Gram-positive bacteria. May protect cells against infection with HIV-1. [a.k.a. NP_001917.1, DEF6_HUMAN, AAH69710.1]

17) '9606.ENSP00000357097':

FCER1A - High affinity immunoglobulin epsilon receptor subunit alpha; Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines. [a.k.a. IgE Fc receptor subunit alpha, R-HSA-2871796, ENST00000392240]

18) '9606.ENSP00000262865':

BPI - Bactericidal permeability-increasing protein; The cytotoxic action of BPI is limited to many species of Gram-negative bacteria; this specificity may be explained by a strong affinity of the very basic N-terminal half for the negatively charged lipopolysaccharides that are unique to the Gram-negative bacterial outer envelope. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa, this activity is inhibited by LPS from P.aeruginosa; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. [a.k.a. Bactericidal permeability increasing protein, P17213, HPA061284]

19) '9606.ENSP00000382250':

MRPS6 - Mitochondrial ribosomal protein S6. [a.k.a. CH471079, R-HSA-5368286, C21orf101]

20) '9606.ENSP00000362082':

CCND3 - G1/S-specific cyclin-D3; Regulatory component of the cyclin D3-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. A [...] [a.k.a. AAM51826.1, CAB000116, R-HSA-69278]

101 query items

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