searching ... STRING: functional protein association networks

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The following proteins in Homo sapiens appear to match your input.
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101 query items

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1) '9606.ENSP00000470034':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

2) '9606.ENSP00000401303':

SHC1 - SHC-transforming protein 1; Signaling adapter that couples activated growth factor receptors to signaling pathways. Participates in a signaling cascade initiated by activated KIT and KITLG/SCF. Isoform p46Shc and isoform p52Shc, once phosphorylated, couple activated receptor tyrosine kinases to Ras via the recruitment of the GRB2/SOS complex and are implicated in the cytoplasmic propagation of mitogenic signals. Isoform p46Shc and isoform p52Shc may thus function as initiators of the Ras signaling cascade in various non-neuronal systems. Isoform p66Shc does not mediate Ras activation, [...] [a.k.a. SHC-transforming protein 1, XP_024304851.1, R-HSA-9026519]

3) '9606.ENSP00000263384':

FAM32A - Protein FAM32A; Isoform 1, but not isoform 2 or isoform 3, may induce G2 arrest and apoptosis. May also increase cell sensitivity to apoptotic stimuli. [a.k.a. OMIM:614554, ENST00000589852, FAM32A-205]

4) '9606.ENSP00000225665':

SLC25A11 - Mitochondrial 2-oxoglutarate/malate carrier protein; Catalyzes the transport of 2-oxoglutarate across the inner mitochondrial membrane in an electroneutral exchange for malate or other dicarboxylic acids, and plays an important role in several metabolic processes, including the malate-aspartate shuttle, the oxoglutarate/isocitrate shuttle, in gluconeogenesis from lactate, and in nitrogen metabolism. Maintains mitochondrial fusion and fission events, and the organization and morphology of cristae. Involved in the regulation of apoptosis (By similarity). Acts as a tumor-suppressor gene i [...] [a.k.a. NP_001158889, ENSG00000108528, NM_001165418]

5) '9606.ENSP00000464327':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

6) '9606.ENSP00000255631':

HSPBP1 - Hsp70-binding protein 1; Inhibits HSPA1A chaperone activity by changing the conformation of the ATP-binding domain of HSPA1A and interfering with ATP binding. Interferes with ubiquitination mediated by STUB1 and inhibits chaperone-assisted degradation of immature CFTR. [a.k.a. ENSP00000465690, Hsp70-interacting protein 2, NP_001284529.1]

7) '9606.ENSP00000253727':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

8) '9606.ENSP00000310491':

ARHGAP1 - Rho GTPase-activating protein 1; GTPase activator for the Rho, Rac and Cdc42 proteins, converting them to the putatively inactive GDP-bound state. Cdc42 seems to be the preferred substrate. [a.k.a. ENST00000527588.5, R-HSA-162582, 1RGP]

9) '9606.ENSP00000303490':

C5orf34 - Uncharacterized protein C5orf34; Chromosome 5 open reading frame 34. [a.k.a. KF457895, XR_001742063.2, URS0000D6EC95]

10) '9606.ENSP00000385025':

SMCR8 - Guanine nucleotide exchange protein SMCR8; Component of the C9orf72-SMCR8 complex, a complex that has guanine nucleotide exchange factor (GEF) activity and regulates autophagy. In the complex, C9orf72 and SMCR8 probably constitute the catalytic subunits that promote the exchange of GDP to GTP, converting inactive GDP-bound RAB8A and RAB39B into their active GTP-bound form, thereby promoting autophagosome maturation. The C9orf72-SMCR8 complex also acts as a negative regulator of autophagy initiation by interacting with the ATG1/ULK1 kinase complex and inhibiting its protein kinase activ [...] [a.k.a. SMCR8-C9orf72 complex subunit, BC142680, Q8TEV9]

11) '9606.ENSP00000295822':

EIF5A2 - Eukaryotic translation initiation factor 5A-2; mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation (By s [...] [a.k.a. ENSG00000163577, UPI0000035FC3, NM_020390.5]

12) '9606.ENSP00000334148':

WDR25 - WD repeat domain 25. [a.k.a. BC003641, ENSP00000334654, XM_011537150.2]

13) '9606.ENSP00000379434':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

14) '9606.ENSP00000358739':

RWDD2A - RWD domain containing 2A. [a.k.a. NM_001322335, NM_001322337.1, NP_001309265.1]

15) '9606.ENSP00000386156':

PYM1 - Partner of Y14 and mago; Key regulator of the exon junction complex (EJC), a multiprotein complex that associates immediately upstream of the exon- exon junction on mRNAs and serves as a positional landmark for the intron exon structure of genes and directs post-transcriptional processes in the cytoplasm such as mRNA export, nonsense-mediated mRNA decay (NMD) or translation. Acts as an EJC disassembly factor, allowing translation-dependent EJC removal and recycling by disrupting mature EJC from spliced mRNAs. Its association with the 40S ribosomal subunit probably prevents a translatio [...] [a.k.a. Partner of Y14 and mago, NP_001137325.1, ENST00000549939.1]

16) '9606.ENSP00000283882':

CFDP1 - Craniofacial development protein 1; May play a role during embryogenesis. [a.k.a. XM_011522814, Craniofacial development protein 1, ENST00000566901]

17) '9606.ENSP00000391942':

NECAP2 - Adaptin ear-binding coat-associated protein 2; Involved in endocytosis. [a.k.a. ENST00000496239.5, ENST00000486390.1, XR_002957109.1]

18) '9606.ENSP00000262482':

RNF167 - E3 ubiquitin-protein ligase RNF167; May act as an E3 ubiquitin-protein ligase, or as part of the E3 complex, which accepts ubiquitin from specific E2 ubiquitin- conjugating enzymes, such as UBE2E1, and then transfers it to substrates, such as SLC22A18. May play a role in growth regulation involved in G1/S transition. [a.k.a. NM_001320361.1, EAW90387.1, RNF167-204]

19) '9606.ENSP00000331087':

TSSC4 - Protein TSSC4; Tumor suppressing subtransferable candidate 4. [a.k.a. ENSG00000184281, ENST00000381005, AAH50616.1]

20) '9606.ENSP00000274242':

RPL37 - 60S ribosomal protein L37; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family. [a.k.a. R-HSA-72737, D6R9X9, R-HSA-2408522]

101 query items

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