searching ... STRING: functional protein association networks

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The following proteins in Homo sapiens appear to match your input.
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101 query items

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1) '9606.ENSP00000477527':

H2BC17 - Histone H2B type 1-O; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. [a.k.a. R-HSA-5693565, R-HSA-5619507, R-HSA-69278]

2) '9606.ENSP00000338165':

TMEM39B - Transmembrane protein 39B; Belongs to the TMEM39 family. [a.k.a. NP_060526, CAB66630.1, XR_002956975.1]

3) '9606.ENSP00000242208':

INHBA - Inhibin beta A chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins; Belongs to the TGF-beta family. [a.k.a. X04447, R-HSA-1502540, 1S4Y]

4) '9606.ENSP00000352252':

H3C12 - Histone H3.1; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. [a.k.a. 5XF3, 5XNV, AAH96131.1]

5) '9606.ENSP00000204517':

TFAP4 - Transcription factor AP-4; Transcription factor that activates both viral and cellular genes by binding to the symmetrical DNA sequence 5'-CAGCTG-3'. [a.k.a. AP-4, TFAP4-203, HGNC:11745]

6) '9606.ENSP00000476136':

H2BC11 - Histone H2B type 1-J; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. [a.k.a. 5XF3, 3WTP, P06899]

7) '9606.ENSP00000219368':

FA2H - Fatty acid 2-hydroxylase; Catalyzes the hydroxylation of free fatty acids at the C-2 position to produce 2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. FA2H is stereospecific for the production of (R)-2- hydroxy fatty acids. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath (By similarity). Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in th [...] [a.k.a. XM_011523317.3, R-HSA-556833, J3QS89]

8) '9606.ENSP00000317891':

TNIP1 - TNFAIP3-interacting protein 1; Inhibits NF-kappa-B activation and TNF-induced NF-kappa-B- dependent gene expression by regulating A20/TNFAIP3-mediated deubiquitination of IKBKG; proposed to link A20/TNFAIP3 to ubiquitinated IKBKG. Involved in regulation of EGF-induced ERK1/ERK2 signaling pathway; blocks MAPK3/MAPK1 nuclear translocation and MAPK1- dependent transcription. Increases cell surface CD4(T4) antigen expression. Involved in the anti-inflammatory response of macrophages and positively regulates TLR-induced activation of CEBPB. Involved in the prevention of autoimmunity; this f [...] [a.k.a. ENSP00000430279, KIAA0113, Q15025]

9) '9606.ENSP00000343027':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

10) '9606.ENSP00000418193':

SPRR2F - Small proline-rich protein 2F; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane (By similarity). [a.k.a. XM_017002176, ENSP00000418193, AL139417]

11) '9606.ENSP00000385675':

IL6 - Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] [a.k.a. C9J5B0, IFN-beta-2, CAA28026.1]

12) '9606.ENSP00000330391':

SPRR3 - Small proline-rich protein 3; Cross-linked envelope protein of keratinocytes. [a.k.a. uc001fax.5, SPRR3-201, AJ243667]

13) '9606.ENSP00000376423':

SPRR2A - Small proline rich protein 2A. [a.k.a. HGNC:11261, CCDS1034.1, AAH96108.1]

14) '9606.ENSP00000357722':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

15) '9606.ENSP00000380933':

- - Sorry, STRING found no proteins by this name in Homo sapiens - -

16) '9606.ENSP00000479355':

LENG9 - Leukocyte receptor cluster member 9. [a.k.a. NP_945339.2, ENST00000611161.1, Leukocyte receptor cluster member 9]

17) '9606.ENSP00000445633':

H2BC8 - H2B clustered histone 8. [a.k.a. CH471087, R-HSA-5693565, R-HSA-5619507]

18) '9606.ENSP00000365201':

PRRC2A - Protein PRRC2A; May play a role in the regulation of pre-mRNA splicing. [a.k.a. CCDS4708.1, OMIM:142580, M33509]

19) '9606.ENSP00000386911':

ARHGAP25 - Rho GTPase-activating protein 25; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. [a.k.a. ENST00000463061.1, XP_016860915.1, ENST00000463483]

20) '9606.ENSP00000481622':

H2BS1 - Histone H2B type F-S; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. [a.k.a. ENSP00000481622, R-HSA-5693565, NP_059141.1]

101 query items

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