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STRINGSTRING
SYNGTS_0883 SYNGTS_0883 rsgA rsgA polA polA pheT pheT SYNGTS_1584 SYNGTS_1584 hup hup hoxU hoxU dnaA dnaA hoxY hoxY hoxH hoxH ssr1765 ssr1765
"hup" - DNA binding protein HU in Synechocystis sp. PCC6803
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hupDNA binding protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions (100 aa)    
Predicted Functional Partners:
SYNGTS_0883
Histidinol-phosphate aminotransferase (368 aa)
              0.875
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box)- 5’-TTATC[CA]A[CA]A-3’. DnaA binds to ATP and to acidic phospholipids (By similarity) (447 aa)
     
 
  0.871
rsgA
Hypothetical protein; May play a role in 30S ribosomal subunit biogenesis. Unusual circulary permuted GTPase that catalyzes rapid hydrolysis of GTP with a slow catalytic turnover (369 aa)
         
  0.828
hoxH
Hydrogenase large subunit (474 aa)
           
  0.779
pheT
phenylalanyl-tRNA synthetase (810 aa)
   
 
  0.769
ssr1765
Hypothetical protein (84 aa)
           
  0.754
SYNGTS_1584
polyA polymerase (942 aa)
         
  0.724
hoxY
Hydrogenase small subunit (182 aa)
           
  0.709
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 3’ to 5’ and 5’ to 3’ exonuclease activity (986 aa)
     
 
  0.698
hoxU
Bidirectional hydrogenase complex protein HoxU (238 aa)
           
  0.676
Your Current Organism:
Synechocystis sp. PCC6803
NCBI taxonomy Id: 1148
Other names: Aphanocapsa sp. (strain N-1), Aphanocapsa sp. N-1, S. sp. PCC 6803, Synechocystis, Synechocystis PCC6803, Synechocystis sp. (ATCC 27184), Synechocystis sp. (PCC 6803), Synechocystis sp. (strain PCC 6803), Synechocystis sp. ATCC 27184, Synechocystis sp. PCC 6803, Synechocystis sp. PCC 6803 A, Synechocystis sp. PCC 6803 B, Synechocystis sp. PCC6803
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