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LJ_0916 LJ_0916 LJ_0013 LJ_0013 glmS glmS pgi pgi pfkA pfkA LJ_0862 LJ_0862 tpiA tpiA LJ_1080 LJ_1080 zwf zwf pgk pgk eno1 eno1
"pgi" - Glucose-6-phosphate isomerase in Lactobacillus johnsonii
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
pgiGlucose-6-phosphate isomerase (447 aa)    
Predicted Functional Partners:
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) (251 aa)
   
 
  0.999
zwf
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone (482 aa)
   
 
  0.998
pgk
Phosphoglycerate kinase (403 aa)
   
   
  0.998
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis (319 aa)
   
  0.996
LJ_0013
Fructokinase (294 aa)
       
  0.995
LJ_0916
Mannose-6-phosphate isomerase (321 aa)
 
 
  0.994
glmS
Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (603 aa)
   
 
  0.988
LJ_1080
Pyruvate kinase (589 aa)
   
   
  0.979
eno1
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (432 aa)
   
 
  0.971
LJ_0862
Phosphomannomutase (574 aa)
 
 
  0.969
Your Current Organism:
Lactobacillus johnsonii
NCBI taxonomy Id: 257314
Other names: L. johnsonii, L. johnsonii NCC 533, Lactobacillus johnsonii, Lactobacillus johnsonii NCC 533
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