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pyk pyk aspC2 aspC2 sucC sucC BF3541 BF3541 mdh mdh sucD sucD pckA pckA maeB maeB fumB fumB aspC1 aspC1 BF1601 BF1601
"mdh" - Malate dehydrogenase in Bacteroides fragilis NCTC9343
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
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Textmining
[Homology]
Score
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate (313 aa)    
Predicted Functional Partners:
BF3541
Citrate synthase (434 aa)
   
  0.995
fumB
Fumarate hydratase class I, anaerobic (548 aa)
   
 
  0.993
aspC2
Aspartate aminotransferase (397 aa)
   
 
  0.981
BF1601
Aspartate aminotransferase (399 aa)
   
 
  0.981
aspC1
Aspartate aminotransferase (397 aa)
   
 
  0.981
pckA
Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA (535 aa)
     
 
  0.980
maeB
Malic enzyme (762 aa)
 
  0.946
sucD
succinyl-CoA synthetase subunit alpha (289 aa)
   
 
  0.930
sucC
succinyl-CoA synthetase subunit beta (382 aa)
   
  0.927
pyk
Pyruvate kinase (485 aa)
   
  0.915
Your Current Organism:
Bacteroides fragilis NCTC9343
NCBI taxonomy Id: 272559
Other names: B. fragilis NCTC 9343, Bacteroides fragilis ATCC 25285, Bacteroides fragilis NCTC 9343, Bacteroides fragilis NCTC9343, Bacteroides fragilis str. NCTC 9343, Bacteroides fragilis strain NCTC 9343
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