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rpsL rpsL rpsK rpsK fusA fusA rpsG rpsG rpsB rpsB rpsD rpsD Sfla_2530 Sfla_2530 rpsJ rpsJ rpsM rpsM rpsE rpsE tsf tsf
"Sfla_2530" - Translation elongation factor Tu in Streptomyces flavogriseus
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second shell of interactors
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experimentally determined
Predicted Interactions
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gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Sfla_2530Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (397 aa)    
Predicted Functional Partners:
tsf
Translation elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (278 aa)
 
  0.997
rpsB
30S ribosomal protein S2 (306 aa)
 
  0.997
rpsG
30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (156 aa)
 
  0.997
rpsL
30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (123 aa)
 
  0.996
rpsJ
Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes (102 aa)
 
  0.995
rpsE
30S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (200 aa)
 
  0.995
rpsM
30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P- sites (126 aa)
 
 
  0.994
rpsD
30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (204 aa)
 
 
  0.992
rpsK
30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (134 aa)
 
  0.991
fusA
Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (709 aa)
 
0.991
Your Current Organism:
Streptomyces flavogriseus
NCBI taxonomy Id: 591167
Other names: Actinomyces flavogriseus, S. flavogriseus, S. flavogriseus ATCC 33331, Streptomyces flavigriseus, Streptomyces flavogriseus, Streptomyces flavogriseus ATCC 33331, Streptomyces flavogriseus str. ATCC 33331, Streptomyces flavogriseus strain ATCC 33331
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