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acl-2 acl-2 C33H5.18 C33H5.18 dgtr-1 dgtr-1 acl-9 acl-9 pld-1 pld-1 acl-8 acl-8 dgk-5 dgk-5 egl-8 egl-8 plc-4 plc-4 plc-1 plc-1 plc-3 plc-3
"dgk-5" - Putative diacylglycerol kinase K06A1.6 in Caenorhabditis elegans
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
dgk-5Putative diacylglycerol kinase K06A1.6 (937 aa)    
Predicted Functional Partners:
egl-8
EGg Laying defective family member (egl-8) ; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes (By similarity). Required in the nervous system to modulate neuronal activity. Facilitates synaptic transmission at neuromuscular junctions by regulating the release of acetylcholine from the motor neurons and thus affecting locomotion. Plays a role in efficient egg laying and defecation (PubMed-10571227, PubMed-10571228, PubMed-24212673). Involved in axon [...] (1431 aa)
     
  0.953
plc-4
PhosphoLipase C family member (plc-4) (751 aa)
     
  0.948
plc-1
PhosphoLipase C family member (plc-1) (1898 aa)
     
  0.948
pld-1
PhosphoLipase D family member (pld-1) (1427 aa)
         
  0.907
C33H5.18
Probable phosphatidate cytidylyltransferase ; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol (PtdIns) (465 aa)
     
 
  0.905
plc-3
PhosphoLipase C family member (plc-3) (1350 aa)
     
    0.905
acl-2
Putative 1-acyl-sn-glycerol-3-phosphate acyltransferase acl-2 ; Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone (282 aa)
     
 
    0.900
acl-9
ACyLtransferase-like family member (acl-9) (399 aa)
         
    0.900
dgtr-1
Protein DGTR-1 (359 aa)
         
    0.900
acl-8
ACyLtransferase-like family member (acl-8) (344 aa)
         
    0.900
Your Current Organism:
Caenorhabditis elegans
NCBI taxonomy Id: 6239
Other names: C. elegans, Caenorhabditis elegans, Rhabditis elegans, nematode
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