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WDR1 WDR1 ACTA1 ACTA1 ACTB ACTB S100B S100B CAPZA1 CAPZA1 CAPZA3 CAPZA3 ACTR2 ACTR2 CAPZA2 CAPZA2 CAPZB CAPZB ARPC2 ARPC2 LRRC16A LRRC16A
"CAPZA1" - F-actin-capping protein subunit alpha-1 in Gallus gallus
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
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textmining
co-expression
protein homology
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Score
CAPZA1F-actin-capping protein subunit alpha-1 ; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. CapZ may mediate the attachment of the barbed ends of actin filaments to the Z-line (287 aa)    
Predicted Functional Partners:
CAPZB
F-actin-capping protein subunit beta isoforms 1 and 2 ; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the regulation of cell morphology and cytoskeletal organization (276 aa)
     
  0.999
LRRC16A
Uncharacterized protein (1323 aa)
     
    0.963
S100B
Uncharacterized protein (92 aa)
       
    0.907
CAPZA2
F-actin-capping protein subunit alpha-2 ; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. CapZ may mediate the attachment of the barbed ends of actin filaments to the Z-line (286 aa)
         
 
0.900
ARPC2
Uncharacterized protein (308 aa)
     
 
  0.896
WDR1
WD repeat-containing protein 1 ; Induces disassembly of actin filaments in conjunction with ADF/cofilin family proteins (603 aa)
     
      0.893
ACTR2
Actin-related protein 2 ; Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament (By similarity) (393 aa)
     
 
  0.858
ACTB
Actin, cytoplasmic type 5 ; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells (376 aa)
     
 
  0.821
ACTA1
Actin, alpha cardiac muscle 1 ; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells (377 aa)
     
 
  0.816
CAPZA3
Uncharacterized protein ; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments (282 aa)
       
0.814
Your Current Organism:
Gallus gallus
NCBI taxonomy Id: 9031
Other names: G. gallus, Gallus, Gallus domesticus, Gallus gallus, Gallus gallus domesticus, Phasianinae, bantam, chicken, chickens, dwarf Leghorn chickens, red junglefowl
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