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AGBL3 AGBL3 ENSG00000157654 ENSG00000157654 R3HCC1 R3HCC1 TMEM247 TMEM247 ACSBG2 ACSBG2 IQCF5 IQCF5 TCP10L TCP10L PRM2 PRM2 BPIFA3 BPIFA3 SMCP SMCP UBE2U UBE2U
"TMEM247" - Transmembrane protein 247 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurence
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Experiments
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[Homology]
Score
TMEM247Transmembrane protein 247 (219 aa)    
Predicted Functional Partners:
R3HCC1
R3H domain and coiled-coil containing 1 (253 aa)
           
  0.583
ENSG00000157654
PALM2-AKAP2 readthrough (1103 aa)
           
  0.573
BPIFA3
BPI fold containing family A, member 3 (254 aa)
     
        0.478
PRM2
Protamine 2; Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis. They compact sperm DNA into a highly condensed, stable and inactive complex (102 aa)
     
        0.475
UBE2U
Ubiquitin-conjugating enzyme E2U (putative); Catalyzes the covalent attachment of ubiquitin to other proteins (226 aa)
     
        0.474
ACSBG2
acyl-CoA synthetase bubblegum family member 2; Mediates activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Able to activate long-chain fatty acids. Also able to activate very long-chain fatty acids; however, the relevance of such activity is unclear in vivo. Has increased ability to activate oleic and linoleic acid. May play a role in spermatogenesis (666 aa)
     
        0.471
AGBL3
ATP/GTP binding protein-like 3; Metallocarboxypeptidase that mediates both deglutamylation and deaspartylation of target proteins. Catalyzes the deglutamylation of polyglutamate side chains generated by post-translational polyglutamylation in proteins such as tubulins. Also removes gene-encoded polyglutamates or polyaspartates from the carboxy-terminus of target proteins such as MYLK. Does not show detyrosinase or deglycylase activities from the carboxy- terminus of tubulin (920 aa)
           
  0.465
TCP10L
T-complex 10-like; May be involved in transcriptional regulation. Has in vitro transcription inhibition activity. Acts as a tumor suppressor in hepatocellular carcinoma (HCC) cells (215 aa)
     
        0.464
SMCP
Sperm mitochondria-associated cysteine-rich protein; Involved in sperm motility. Its absence is associated with genetic background dependent male infertility. Infertility may be due to reduced sperm motility in the female reproductive tract and inability to penetrate the oocyte zona pellucida (By similarity) (116 aa)
     
        0.459
IQCF5
IQ motif containing F5 (148 aa)
     
        0.455
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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