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MAGEA9B MAGEA9B H2BFM H2BFM CXorf40A CXorf40A RUSC2 RUSC2 AEN AEN MT2A MT2A
"CXorf40A" - Chromosome X open reading frame 40A in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurence
Coexpression
Experiments
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Textmining
[Homology]
Score
CXorf40AChromosome X open reading frame 40A; May have an important role of cell protection in inflammation reaction (158 aa)    
Predicted Functional Partners:
RUSC2
RUN and SH3 domain containing 2 (1516 aa)
           
  0.612
MT2A
Metallothionein 2A; Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids (61 aa)
       
 
  0.547
H2BFM
H2B histone family, member M; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (154 aa)
           
  0.535
MAGEA9B
Melanoma antigen family A, 9B (315 aa)
           
  0.442
AEN
Apoptosis enhancing nuclease; Exonuclease with activity against single- and double- stranded DNA and RNA. Mediates p53-induced apoptosis. When induced by p53 following DNA damage, digests double-stranded DNA to form single-stranded DNA and amplifies DNA damage signals, leading to enhancement of apoptosis (325 aa)
           
  0.424
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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