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AR AR KAT2A KAT2A KAT2B KAT2B EP300 EP300 NCOA1 NCOA1 NCOA3 NCOA3 RXRB RXRB MAPK6 MAPK6 RXRG RXRG C-ERBA-B1 C-ERBA-B1 MAPK4 MAPK4
"NCOA3" - Nuclear receptor coactivator 3 in Sus scrofa
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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NCOA3Nuclear receptor coactivator 3 (1390 aa)    
Predicted Functional Partners:
NCOA1
Nuclear receptor coactivator 1 ; Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Involved in the coactivation of different nuclear receptors, such as for steroids (PGR, GR and ER), retinoids (RXRs), thyroid hormone (TRs) and prostanoids (PPARs). Also involved in coactivation mediated by STAT3, STAT5A, STAT5B and STAT6 transcription factors. Displays histone acetyltransferase activity toward H3 and H4; the relevance of such activity remains however unclear. Plays a central role in creating m [...] (1441 aa)
     
0.989
EP300
Uncharacterized protein (2421 aa)
       
  0.981
KAT2B
Uncharacterized protein (692 aa)
       
  0.976
AR
Androgen receptor ; Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins. Transcription activation is down-regulated by NR0B2. Activated, but not phosphorylated, by HIPK3 and ZIPK/DAPK3 (896 aa)
       
  0.971
KAT2A
Uncharacterized protein (837 aa)
       
  0.944
MAPK6
Uncharacterized protein (722 aa)
     
  0.932
MAPK4
Uncharacterized protein (590 aa)
     
  0.931
C-ERBA-B1
Uncharacterized protein (461 aa)
       
  0.924
RXRB
Retinoic acid receptor RXR-beta (532 aa)
       
  0.924
RXRG
Retinoic acid receptor RXR-gamma ; Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5’-AGGTCA-3’ sites known as DR1-DR5. The high affinity ligand for RXRs is 9-cis retinoic acid (By similarity) (463 aa)
       
  0.924
Your Current Organism:
Sus scrofa
NCBI taxonomy Id: 9823
Other names: S. scrofa, Suidae, Suiformes, Suina, Sus, Sus scrofa, boars, pig, pigs, swine, wild boar
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