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PSMC1 PSMC1 PSMD3 PSMD3 PSMD11 PSMD11 PSMA5 PSMA5 PSMC5 PSMC5 PSMD14 PSMD14 PSMD1 PSMD1 PSMA2 PSMA2 PSMC6 PSMC6 PSMA4 PSMA4 PSMD4 PSMD4
"PSMD4" - 26S proteasome non-ATPase regulatory subunit 4 in Bos taurus
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
PSMD426S proteasome non-ATPase regulatory subunit 4 ; Binds and presumably selects ubiquitin-conjugates for destruction. Displays selectivity for longer polyubiquitin chains. Modulates intestinal fluid secretion (By similarity) (382 aa)    
Predicted Functional Partners:
PSMC1
26S protease regulatory subunit 4 (440 aa)
     
  0.999
PSMD11
26S proteasome non-ATPase regulatory subunit 11 ; Component of the lid subcomplex of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. In the complex, PSMD11 is required for proteasome assembly. Plays a key role in increased proteasome activity in embryonic stem cells (ESCs)- its high expression in ESCs promotes enhanced assembly of the 26S proteasome, followed by higher proteasome activity (By similarity) (422 aa)
     
  0.999
PSMC5
26S protease regulatory subunit 8 ; The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex (406 aa)
     
  0.999
PSMA5
Proteasome subunit alpha type-5 ; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity (By similarity) (241 aa)
     
  0.999
PSMA2
Proteasome subunit alpha type-2 ; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. PSMA2 may have a potential regulatory effect on another component(s) of the proteasome complex through tyrosine phosphorylation (By similarity) (234 aa)
     
  0.999
PSMD3
26S proteasome non-ATPase regulatory subunit 3 ; Acts as a regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins (534 aa)
     
  0.999
PSMD1
26S proteasome non-ATPase regulatory subunit 1 (953 aa)
     
  0.999
PSMA4
Proteasome subunit alpha type-4 ; The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity (By similarity) (261 aa)
     
  0.999
PSMC6
26S protease regulatory subunit 10B ; The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex (By similarity) (389 aa)
     
  0.999
PSMD14
26S proteasome non-ATPase regulatory subunit 14 (310 aa)
     
  0.999
Your Current Organism:
Bos taurus
NCBI taxonomy Id: 9913
Other names: B. taurus, Bos, Bos bovis, Bos primigenius taurus, Bos taurus, Bovidae, Bovidae sp. Adi Nefas, Bovinae, Pecora, Ruminantia, bovine, cattle, cow, domestic cattle, domestic cow, oxen, cattle
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