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6564 matches

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organism

protein

Homo sapiens

LIG1 - DNA ligase 1; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair; Belongs to the ATP-dependent DNA ligase family. [a.k.a. R-HSA-162587, 3978, P18858]

Homo sapiens

LIG4 - DNA ligase 4; Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA non- homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends. [a.k.a. NP_001091738, R-HSA-162587, NM_001352604.1]

Homo sapiens

HLTF - Helicase-like transcription factor; Has both helicase and E3 ubiquitin ligase activities. Possesses intrinsic ATP-dependent nucleosome-remodeling activity; This activity may be required for transcriptional activation or repression of specific target promoters (By similarity). These may include the SERPINE1 and HIV-1 promoters and the SV40 enhancer, to which this protein can bind directly. Plays a role in error-free postreplication repair (PRR) of damaged DNA and maintains genomic stability through acting as a ubiquitin ligase for 'Lys-63'-linked polyubiquitination of chromatin-bound PCNA. [a.k.a. 4HRH, Q14527, NM_139048.2]

Mus musculus

Lig4 - DNA ligase 4; Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA nonhomologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends. [a.k.a. ENSMUSG00000049717, ENSMUSP00000130807, Lig4-201]

Mus musculus

Hltf - Helicase-like transcription factor; Has both helicase and E3 ubiquitin ligase activities. Possesses intrinsic ATP-dependent nucleosome-remodeling activity. This activity may be required for transcriptional activation or repression of specific target promoters (By similarity). These may include the SERPINE1, to which this protein can bind directly. Plays a role in error-free postreplication repair (PRR) of damaged DNA and maintains genomic stability through acting as a ubiquitin ligase for 'Lys-63'- linked polyubiquitination of chromatin-bound PCNA (By similarity). [a.k.a. ENSMUSP00000002502, Hltf-206, XP_006535491.1]

Drosophila melanogaster

DNAlig4 - DNA ligase 4 (DNAlig4) encodes an ATP-dependent DNA ligase responsible for the sealing of DNA double-strand breaks during the canonical non-homologous end joining pathway of DNA repair. It interacts with the product of XRCC4 for stability and DNA ligase activity. [a.k.a. FBgn0030506, DNAlig4-PA, NM_132679]

Drosophila melanogaster

DNAlig3 - DNA ligase 3 (DNAlig3) encodes an ATP-dependent DNA ligase that is involved in the repair of nuclear and mitochondrial single- and double-strand DNA breaks. [a.k.a. FBgn0286075, DNAlig3-PA, 7227.FBpp0082071]

Saccharomyces cerevisiae

DNL4 - DNA ligase required for nonhomologous end-joining (NHEJ); forms stable heterodimer with required cofactor Lif1p, interacts with Nej1p; involved in meiosis, not essential for vegetative growth; mutations in human ortholog lead to ligase IV syndrome and Dubowitz syndrome; Belongs to the ATP-dependent DNA ligase family. [a.k.a. YOR005C, DNA ligase II, UND407]

Saccharomyces cerevisiae

RAD16 - Nucleotide excision repair (NER) protein; binds damaged DNA during NER; binds DNA in an ATP-dependent manner (with Rad7p) during NER; required for NER of non-transcribed chromatin; subunit of Nucleotide Excision Repair Factor 4 (NEF4) and the Elongin-Cullin-Socs (ECS) ligase complex. [a.k.a. YBR114W, S000000318, NM_001178462.1]

10)

Saccharomyces cerevisiae

RAD7 - Nucleotide excision repair (NER) protein; binds damaged DNA during NER; binds DNA in an ATP-dependent manner (with Rad16p) during NER; required for repair of non-transcribed chromatin; subunit of Nucleotide Excision Repair Factor 4 (NEF4) and the Elongin-Cullin-Socs (ECS) ligase complex. [a.k.a. YJR052W, L000001561, DNA repair protein RAD7]

11)

Saccharomyces cerevisiae

ULS1 - ATP-dependent helicase ULS1; Swi2/Snf2-related translocase, SUMO-Targeted Ubiquitin Ligase (STUbL); required for maintenance of NHEJ inhibition at telomeres; functions at telomeres to translocate and ubiquitinylate poly-sumoylated Rap1p for proteosomal degradation; plays role in antagonizing silencing during mating-type switching; only known STUbL with a translocase activity; contains RING finger domain; relocalizes from nucleus to cytoplasm upon DNA replication stress. [a.k.a. YOR191W, CAA99400.1, NP_014834]

12)

Acaromyces ingoldii

A0A316YWT7 - ATP-dependent DNA ligase. [a.k.a. A0A316YWT7, FA10DRAFT_263828, A0A316YWT7_9BASI, ATP-dependent DNA ligase]

13)

Acetobacter aceti

AQS84470.1 - ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. [a.k.a. A0U92_06425, 6.5.1.6, aace:A0U92_06425, ATP-dependent DNA ligase]

14)

Acetobacter persici

A0U91_05710 - ATP-dependent DNA ligase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. [a.k.a. aper:A0U91_05710, A0A1U9LDM7, Hypothetical protein, ATP-dependent DNA ligase]

15)

Achromobacter arsenitoxydans

KYC_21586 - COG1793 ATP-dependent DNA ligase. [a.k.a. EHK64140.1, H0FC08_9BURK, WP_008166237.1, ATP-dependent DNA ligase]

16)

Achromobacter denitrificans

ligD - ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. [a.k.a. BVK87_28230, OLU01196.1, DNA ligase D, ATP-dependent DNA ligase]

17)

Achromobacter piechaudii

ligD - COG1793 ATP-dependent DNA ligase. [a.k.a. QWC_00630, EJO33461.1, WP_050728754.1, ATP-dependent DNA ligase]

18)

Achromobacter piechaudii

QWC_17927 - ATP dependent DNA ligase; COG0666 FOG: Ankyrin repeat. [a.k.a. EJO29983.1, EJO29983, A0A0L6I809, ATP-dependent DNA ligase]

19)

Achromobacter piechaudii

QWC_22169 - COG1793 ATP-dependent DNA ligase. [a.k.a. EJO29269.1, EJO29269, 6.5.1.1, ATP-dependent DNA ligase]

20)

Achromobacter sp. Root83

KRC70162.1 - ATP-dependent DNA ligase; Catalyzes the ATP-dependent formation of a phosphodiester at the site of a single strand break in duplex DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. [a.k.a. ASE30_16845, KRC70162, A0A0Q8WVD0, ATP-dependent DNA ligase]

6564 matches

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