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RB1 - Retinoblastoma-associated protein; Key regulator of entry into cell division that acts as a tumor suppressor. Promotes G0-G1 transition when phosphorylated by CDK3/cyclin-C. Acts as a transcription repressor of E2F1 target genes. The underphosphorylated, active form of RB1 interacts with E2F1 and represses its transcription activity, leading to cell cycle arrest. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransfer [...]
[a.k.a. RB1-001, p105-Rb, M27857,
Enterococcus faecalis V583
rpmD - 50S ribosomal protein L30; Similar to SP:P19947, GB:M15400, GB:L11910, GB:M27845, GB:M27846, GB:M27847, GB:M27848, GB:M27849, GB:M27850, GB:M27851, GB:L35146, GB:M27852, GB:M27853, GB:M27854, GB:M27855, GB:M27856, GB:M27857, GB:M27858, GB:M27859, GB:M27860, GB:L35147, GB:M27862, GB:M27863, GB:M27864, GB:M27865, GB:M27866, GB:M28419, GB:M33647, GB:L41892, GB:L41915, GB:L41921, GB:L41904, GB:L41898, GB:L41923, GB:L42000, GB:L41891, GB:L49214, GB:L41897, GB:L49215, GB:L49216, GB:L41899, GB:L49233, GB:L41911, GB:L41890, GB:L41894, GB:L41900, GB:S67080, SP:P06400, PID:1088319, PID:1088325, [...]
[a.k.a. RpmD, EF_0225, AAO80093.1]
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SIB - Swiss Institute of Bioinformatics
CPR - Novo Nordisk Foundation Center Protein Research
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