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Ptprc - Receptor-type tyrosine-protein phosphatase C; Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN (By similarity). Dephosphorylates LYN, and thereby modulates LYN activity
[a.k.a. Ly-5, ENSMUST00000182755, Ptprc-006,
Sca_1952 - Uncharacterized protein; (
) Leukocyte common antigen precursor (EC 18.104.22.168) (L-CA) (Lymphocyte common antigen Ly-5) (CD45) (T200); Hypothetical protein; Sca_1952
[a.k.a. SCA_1952, CAL28858.1, CAL28858]
© STRING Consortium 2020
SIB - Swiss Institute of Bioinformatics
CPR - Novo Nordisk Foundation Center Protein Research
EMBL - European Molecular Biology Laboratory
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