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Smarca2 - Probable global transcription activator SNF2L2; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Binds DNA non-specifically. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural develop [...]
[a.k.a. Snf2l2, Baf190b, Snf2a,
Krac_8539 - KEGG: Smarca2; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2; K11647 SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2/4; SPTR:
[a.k.a. EFH87210.1, 297553345, D6TN60]
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SIB - Swiss Institute of Bioinformatics
CPR - Novo Nordisk Foundation Center Protein Research
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