creC - STRING protein network

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organism

protein

Escherichia coli K12 MG1655

creC - Sensor protein CreC; Member of the two-component regulatory system CreC/CreB involved in catabolic regulation. CreC may function as a membrane- associated protein kinase that phosphorylates CreB in response to environmental signals. CreC can also phosphorylate PhoB

Homo sapiens

RCN3 - Reticulocalbin-3; EF-hand domain containing; Belongs to the CREC family [a.k.a. UNQ239/PRO272, HPA043134, AY195859]

Homo sapiens

SDF4 - 45 kDa calcium-binding protein; May regulate calcium-dependent activities in the endoplasmic reticulum lumen or post-ER compartment; Belongs to the CREC family [a.k.a. PSEC0034, CAB45, AAD51612.1]

Homo sapiens

CALU - Calumenin; Involved in regulation of vitamin K-dependent carboxylation of multiple N-terminal glutamate residues. Seems to inhibit gamma-carboxylase GGCX. Binds 7 calcium ions with a low affinity (By similarity); Belongs to the CREC family [a.k.a. uc003vnr.3, AAC17216.1, uc003vnq.3]

Acinetobacter calcoaceticus

creC - annotation not available

Alcanivorax dieselolei

creC - annotation not available

Aspergillus clavatus

creC - Probable catabolite repression protein creC; Component of the regulatory network controlling carbon source utilization through ubiquitination and deubiquitination involving creA, creB, creC, creD and acrB. Required to prevent the proteolysis of the CreB deubiquitinating enzyme in the absence of carbon catabolite repression. CreB deubiquitinating enzyme stabilized in a complex with the CreC leads to the expression of genes such as those in the proline and quinate pathways (By similarity)

Aspergillus flavus

Aspergillus fumigatus

Aspergillus nidulans

creC - Catabolite repression protein creC; Component of the regulatory network controlling carbon source utilization through ubiquitination and deubiquitination involving creA, creB, creC, creD and acrB. Required to prevent the proteolysis of the CreB deubiquitinating enzyme in the absence of carbon catabolite repression. CreB deubiquitinating enzyme stabilized in a complex with the CreC leads to the expression of genes such as those in the proline and quinate pathways

Azoarcus sp. BH72

creC - Catabolite repression sensor kinase for PhoB; Sensor protein creC,; High confidence in function and specificity

Burkholderia cenocepacia

creC - annotation not available

Buttiauxella agrestis

creC - Two-component system response regulator; Overlaps another CDS with the same product name; Protein involved in signal transducer activity, phosphorelay sensor kinase activity, ATP binding, peptidyl-histidine phosphorylation and signal transduction

Cellvibrio japonicus

creC - Histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518

Cellvibrio sp. BR

creC - annotation not available

Cesiribacter andamanensis

creC - annotation not available

Citrobacter farmeri

creC - annotation not available

Citrobacter rodentium

creC - annotation not available

Citrobacter youngae

creC - Sensor protein CreC; KEGG: ssn:SSON_4549 5.3e-207 creC; sensory histidine kinase CreC ; K07641 two-component system, OmpR family, sensor histidine kinase CreC; Psort location: CytoplasmicMembrane, score: 10.00

Cladophialophora carrionii

creC - Catabolite repression protein creC

Collimonas fungivorans

creC - annotation not available

Cupriavidus metallidurans

creC - annotation not available

Cupriavidus taiwanensis

creC - Sensory histidine kinase; Evidence 2b : Function of strongly homologous gene; Product type rc : receptor

Dorea longicatena AGR2136

creC - annotation not available

Eikenella corrodens ATCC23834

creC - ATPase/histidine kinase/DNA gyrase B/HSP90 domain protein; KEGG: pae:PA0464 8.8e-53 creC; two-component sensor CreC K07641; Psort location: CytoplasmicMembrane, score: 9.82

Enterobacter cloacae EcWSU1

creC - annotation not available

Escherichia albertii KF1

creC - annotation not available

Escherichia albertii TW07627

creC - Sensor protein CreC; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518

Escherichia coli BL21

creC - annotation not available

Escherichia coli CFT073

creC - Sensor protein creC; Escherichia coli K-12 ortholog: b4399; Escherichia coli O157:H7 ortholog: z6002

Escherichia coli K12 W3110

Escherichia hermannii

creC - annotation not available

Gammaproteobacteria bacterium HTCC5015

creC - annotation not available

Geobacter daltonii

creC - Sensor histidine kinase CreC, HAMP domain-containing; Domains: HAMP, HisKA, HATPase_c

Janthinobacterium lividum

creC - annotation not available

Neosartorya fischeri

Pseudomonas aeruginosa

creC - annotation not available

Pseudomonas alcaligenes NBRC14159

creC - annotation not available

Pseudomonas entomophila

creC - Histidine kinase; Evidence 2b : Function of strongly homologous gene; Product type r : regulator

Pseudomonas fluorescens F113

creC - Histidine kinase; Two-component response regulator CreC; Protein involved in two-component sensor activity, ATP binding, two-component signal transduction system (phosphorelay), peptidyl-histidine phosphorylation and signal transduction

Pseudomonas fluorescens Pf01

creC - annotation not available

Pseudomonas fluorescens Q287

creC - Histidine kinase; Identified by similarity to SP:P08401; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518

Pseudomonas fluorescens SBW25

creC - annotation not available

Pseudomonas knackmussii

creC - Histidine kinase; Member of the two-component regulatory system CreC/CreB involved in catabolic regulation. CreC may function as a membrane- associated protein kinase that phosphorylates CreB in response to environmental signals. CreC can also phosphorylate PhoB

Pseudomonas protegens CHA0

creC - annotation not available

Pseudomonas protegens Pf5

creC - Histidine kinase; Identified by similarity to SP:P08401; match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518

Pseudomonas pseudoalcaligenes CECT5344

creC - Signal transduction histidine kinase

Pseudomonas putida NBRC14164

creC - annotation not available

Pseudomonas sp. RIT357

creC - annotation not available

Pseudomonas sp. UW4

creC - Histidine kinase; [T] COG0642 Signal transduction histidine kinase

Psychrobacter sp. 1501

creC - Sensor histidine kinase; COG: COG0642

Rubrivivax gelatinosus

creC - annotation not available

Salmonella bongori NCTC12419

creC - annotation not available

Salmonella enterica CT18

creC - annotation not available

Serratia marcescens Db11

creC - annotation not available

Serratia sp. DD3

creC - annotation not available

Shigella flexneri

creC - Sensor protein CreC; Code: T; COG: COG0642

Streptococcus merionis

creC - annotation not available

Thalassobacter stenotrophicus

creC - Sensor protein CreC; Derived by automated computational analysis using gene prediction method: Protein Homology

Trabulsiella guamensis

creC - Two-component system response regulator; Overlaps another CDS with the same product name; Protein involved in signal transducer activity, ATP binding, phosphorelay sensor kinase activity, peptidyl-histidine phosphorylation and signal transduction

Trichoderma reesei

crec - Predicted protein

Vibrio azureus

creC - annotation not available

Vibrio nigripulchritudo

creC - Sensor protein creC; Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type r : regulator

Vibrio proteolyticus

creC - annotation not available

Vibrio scophthalmi

creC - COG0642 Signal transduction histidine kinase

Wolinella succinogenes

CREC - annotation not available

Xanthomonas axonopodis citri

creC - Two-component system sensor protein; Identified by sequence similarity; putative; ORF located using Blastx/Glimmer/Genemark

Xanthomonas campestris campestris

creC - Two-component system sensor protein; Signal transduction histidine kinase

Xanthomonas campestris vesicatoria

creC - annotation not available

Xanthomonas hortorum

creC - annotation not available

Xanthomonas oryzae PXO99A

creC - annotation not available

Yersinia aldovae

creC - Similar to sensory histidine kinase CreC PRK11100; similar to Sensor protein creC of Gammaproteobacteria UniRef RepID=CREC_ECOLI

Yersinia enterocolitica 8081

creC - annotation not available

Yersinia enterocolitica LC20

creC - annotation not available

Yersinia massiliensis

creC - annotation not available

Yersinia pestis CO92

creC - Similar to Myxococcus xanthus developmental histidine kinase sensor SasS TR:O52223 (EMBL:AF029787) (497 aa) fasta scores: E(): 1.4e-23, 28.2% id in 485 aa, and to Escherichia coli sensor protein CreC SW:CREC_ECOLI (P08401) (474 aa) fasta scores: E(): 0, 58.3% id in 470 aa. Probable sensor kinase protein of two-component regulatory system

Yersinia pseudotuberculosis

creC - annotation not available

Aspergillus terreus

ATEG_05873 - Probable catabolite repression protein creC; Component of the regulatory network controlling carbon source utilization through ubiquitination and deubiquitination involving creA, creB, creC, creD and acrB. Required to prevent the proteolysis of the CreB deubiquitinating enzyme in the absence of carbon catabolite repression. CreB deubiquitinating enzyme stabilized in a complex with the CreC leads to the expression of genes such as those in the proline and quinate pathways (By similarity) [a.k.a. creC, CADATEAT00000636, XM_001215051]

Escherichia coli O157H7

ECs5357 - Catabolite repression sensor kinase for PhoB; Corresponds to locus_tag Z6002 [a.k.a. creC, EDL933_5743, AIG71880.1]

Lysobacter antibioticus

LA76x_3566 - annotation not available [a.k.a. creC, ALN64717, HAMP domain protein]

Aeromonas hydrophila YL17

AHV37220.1 - Response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation; Derived by automated computational analysis using gene prediction method: Protein Homology [a.k.a. A9R12_04720, AI20_19210, ahd:AI20_19210]

Capnocytophaga sp. F0087

KHE68250.1 - Uncharacterized protein; KEGG: lbi:LEPBI_I0396 0.0030 creC; sensory histidine kinase CreC K07641 [a.k.a. HMPREF9074_09218, GI:725815271, KHE68250]

Capnocytophaga sp. F0381

EKY07360.1 - Uncharacterized protein; KEGG: lbf:LBF_0384 0.00036 sensory histidine kinase CreC; K07641 two-component system, OmpR family, sensor histidine kinase CreC; Psort location: Cytoplasmic, score: 8.96 [a.k.a. HMPREF9075_02105, EKY07360, hypothetical protein]

Citrobacter amalonaticus

DQ02_03645 - Response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation; Derived by automated computational analysis using gene prediction method: Protein Homology [a.k.a. AL012_08810, KEY50375.1, A0A083ZBE6]

Enterobacter sp. R4368

H650_18920 - Response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation; Derived by automated computational analysis using gene prediction method: GeneMarkS+ [a.k.a. AGN87107.1, R9VQW1_9ENTR, GI:511529567]

Klebsiella oxytoca

KGZ21386.1 - Response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation; Derived by automated computational analysis using gene prediction method: Protein Homology [a.k.a. AB185_32070, MC52_12135, A0A0G3SFZ8_KLEOX]

Klebsiella pneumoniae

JG24_29390 - Response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation; Derived by automated computational analysis using gene prediction method: Protein Homology [a.k.a. KHE28221.1, W1DIH5_KLEPN, kpb:FH42_20795]

Lysobacter daejeonensis

N800_14095 - Response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation; Derived by automated computational analysis using gene prediction method: Protein Homology [a.k.a. KGM55450.1, A0A0A0EYV6_9GAMM, 699268047]

Neurospora crassa

3873726 - Putative WD40 repeat protein CreC; Catabolite repression protein creC [a.k.a. GE21DRAFT_9173, A0A0B0E1Q5, EFNCRP00000003634]

Pseudomonas brassicacearum

CD58_27300 - Response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation; Derived by automated computational analysis using gene prediction method: Protein Homology [a.k.a. AHL36345.1, W8QJ89_9PSED, WP_025215853.1]

Pseudomonas chlororaphis

EY04_32025 - Response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation; Derived by automated computational analysis using gene prediction method: Protein Homology [a.k.a. AIC23384.1, AIC23384, pch:EY04_32025]

Pseudomonas mosselii

AIN61517.1 - Response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation; Derived by automated computational analysis using gene prediction method: Protein Homology [a.k.a. O165_025590, 684199288, A0A088NWA0_9PSED]

Pseudomonas pseudoalcaligenes AD6

N619_08365 - Response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation; Derived by automated computational analysis using gene prediction method: Protein Homology [a.k.a. EZH76520.1, AU05_04360, A0A0F3GD97_PSEPS]

Pseudomonas simiae

AIB38995.1 - Response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation [a.k.a. SAMN05216248_103116, PS417_26140, WP_010207068.1]

Pseudomonas sp. H2

MD26_20660 - Response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation; Derived by automated computational analysis using gene prediction method: Protein Homology [a.k.a. KGI91383.1, 693760183, A0A099DZ13]

Pseudomonas taeanensis

KFX70472.1 - Response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation; Derived by automated computational analysis using gene prediction method: Protein Homology [a.k.a. TMS3_0100570, GI:680315456, KFX70472]

Ralstonia pickettii DTP0602

N234_01340 - Sensor histidine kinase; K07641: creC; two-component system, OmpR family, sensor histidine kinase CreC [EC:2.7.13.3] [a.k.a. AGW88652.1, U3QKP3, sensor histidine kinase]

Salmonella enterica Typhimurium

DD95_14920 - Response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation; Derived by automated computational analysis using gene prediction method: Protein Homology [a.k.a. CR079_09655, CR081_01460, CR082_01050]

Serratia fonticola RB25

Z042_06595 - Response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation; Derived by automated computational analysis using gene prediction method: Protein Homology [a.k.a. AHG19322.1, W0LAL2, WP_024910039.1]

Serratia grimesii

CR62_20630 - Response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation; Derived by automated computational analysis using gene prediction method: Protein Homology [a.k.a. KFB89322.1, A0A084YVS8, KFB89322]

Serratia plymuthica

M621_20695 - Response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation; Derived by automated computational analysis using gene prediction method: Protein Homology [a.k.a. AHY09028.1, sch_21550, GI:619733788]

Serratia sp. Ag1

IV04_03360 - Response regulator in two-component regulatory system with CreC; CreB protein is phosphorylated by sensor protein phospho-CreC; involved in catabolic regulation; Derived by automated computational analysis using gene prediction method: Protein Homology [a.k.a. KFL00076.1, GI:674730227, A0A087L623]

Accumulibacter phosphatis

ACV35149.1 - Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: dar:Daro_3177 sensory histidine kinase CreC [a.k.a. CAP2UW1_1850, InterPro:IPR003661, ACV35149]

Aeromonas hydrophila YL17

AHV37221.1 - Two-component system sensor histidine kinase CreC; Part of a two-component regulatory system with CreB or PhoB; involved in catabolic regulation; Derived by automated computational analysis using gene prediction method: Protein Homology [a.k.a. A9R12_04715, AI20_19215, 604187778]

Arthroderma otae

MCYG_00491 - Catabolite repression protein creC [a.k.a. C5FCR9_ARTOC, C5FCR9, GeneID:9225609]

Aspergillus clavatus

creB - Probable ubiquitin carboxyl-terminal hydrolase creB; Ubiquitin thioesterase component of the regulatory network controlling carbon source utilization through ubiquitination and deubiquitination involving creA, creB, creC, creD and acrB. Deubiquitinates the creA catabolic repressor and the quinate permease qutD. Plays also a role in response to carbon starvation and the control of extracellular proteases activity (By similarity) [a.k.a. ACLA_051880, Ubiquitin-specific-processing protease creB, XP_001272142]

Aspergillus clavatus

acrB - Probable ubiquitination network signaling protein acrB; Component of the regulatory network controlling carbon source utilization through ubiquitination and deubiquitination involving creA, creB, creC, creD and acrB. Involved in resistance to acriflavine, and required for normal growth on a range of sole carbon sources, including fructose, cellobiose, raffinose, and starch, and reduced utilization of amino acids, including GABA and beta-alanine, as sole carbon and nitrogen sources (By similarity) [a.k.a. ACLA_051770, acr2, XP_001272131.1]

Aspergillus clavatus

creA - Probable DNA-binding protein creA; Transcription regulator component of the regulatory network controlling carbon source utilization through ubiquitination and deubiquitination involving creA, creB, creC, creD and acrB. Represses the transcription of the alcR, alcA and aldA genes by binding to a GC-rich region in their promoter. Plays also a role in response to carbon starvation and the control of extracellular proteases activity (By similarity); Belongs to the creA/MIG C2H2-type zinc-finger protein family [a.k.a. ACLA_070730, 4708318, Probable DNA-binding protein creA]

Aspergillus clavatus

creD - Probable HECT-type ubiquitin ligase-interacting protein creD; Component of the regulatory network controlling carbon source utilization through ubiquitination and deubiquitination involving creA, creB, creC, creD and acrB. May be involved in signaling by recognizing appropriately phosphorylated substrates via its arrestin domains and then recruit a HECT-type ubiquitin ligase such as hulA, leading to ubiquitination of the substrate, providing a link between ubiquitination and phosphorylation in protein regulation and stability (By similarity) [a.k.a. ACLA_082820, act:ACLA_082820, XP_001268017]

Aspergillus flavus

creB - Probable ubiquitin carboxyl-terminal hydrolase creB; Ubiquitin thioesterase component of the regulatory network controlling carbon source utilization through ubiquitination and deubiquitination involving creA, creB, creC, creD and acrB. Deubiquitinates the creA catabolic repressor and the quinate permease qutD. Plays also a role in response to carbon starvation and the control of extracellular proteases activity (By similarity) [a.k.a. AFLA_051480, afv:AFLA_051480, Ubiquitin-specific-processing protease creB]

Aspergillus fumigatus

creA - Probable DNA-binding protein creA; Transcription regulator component of the regulatory network controlling carbon source utilization through ubiquitination and deubiquitination involving creA, creB, creC, creD and acrB. Represses the transcription of the alcR, alcA and aldA genes by binding to a GC-rich region in their promoter. Plays also a role in response to carbon starvation and the control of extracellular proteases activity (By similarity); Belongs to the creA/MIG C2H2-type zinc-finger protein family [a.k.a. AFUA_2G11780, XP_755510, Probable DNA-binding protein creA]

Aspergillus fumigatus

creB - Probable ubiquitin carboxyl-terminal hydrolase creB; Ubiquitin thioesterase component of the regulatory network controlling carbon source utilization through ubiquitination and deubiquitination involving creA, creB, creC, creD and acrB. Deubiquitinates the creA catabolic repressor and the quinate permease qutD. Plays also a role in response to carbon starvation and the control of extracellular proteases activity (By similarity) [a.k.a. AFUA_4G12910, Ubiquitin-specific-processing protease creB, EC 3.4.19.12]

Aspergillus fumigatus

Aspergillus nidulans

AN4170.2 - HECT-type ubiquitin ligase-interacting protein creD; Component of the regulatory network controlling carbon source utilization through ubiquitination and deubiquitination involving creA, creB, creC, creD and acrB. May be involved in signaling by recognizing appropriately phosphorylated substrates via its arrestin domains and then recruit a HECT-type ubiquitin ligase such as hulA, leading to ubiquitination of the substrate, providing a link between ubiquitination and phosphorylation in protein regulation and stability [a.k.a. cre-34, AN4170, creD]

Aspergillus nidulans

acrB - Ubiquitination network signaling protein acrB; Component of the regulatory network controlling carbon source utilization through ubiquitination and deubiquitination involving creA, creB, creC, creD and acrB. Involved in resistance to acriflavine, and required for normal growth on a range of sole carbon sources, including fructose, cellobiose, raffinose, and starch, and reduced utilization of amino acids, including GABA and beta-alanine, as sole carbon and nitrogen sources [a.k.a. AN3597, acr2, Ubiquitination network signaling protein acrB]

Aspergillus nidulans

AN3587.2 - Ubiquitin carboxyl-terminal hydrolase creB; Ubiquitin thioesterase component of the regulatory network controlling carbon source utilization through ubiquitination and deubiquitination involving creA, creB, creC, creD and acrB. Deubiquitinates the creA catabolic repressor and the quinate permease qutD. Plays also a role in response to carbon starvation and the control of extracellular proteases activity [a.k.a. AN3587, creB, molB]

Aspergillus nidulans

AN6195.2 - DNA-binding protein creA; Transcription regulator component of the regulatory network controlling carbon source utilization through ubiquitination and deubiquitination involving creA, creB, creC, creD and acrB. Represses the transcription of the alcR, alcA and aldA genes by binding to a GC-rich region in their promoter. Plays also a role in response to carbon starvation and the control of extracellular proteases activity; Belongs to the creA/MIG C2H2-type zinc-finger protein family [a.k.a. creA, AN6195, XP_663799]

Aspergillus niger

creA - DNA-binding protein creA; Transcription regulator component of the regulatory network controlling carbon source utilization through ubiquitination and deubiquitination involving creA, creB, creC, creD and acrB. Represses the transcription of the alcR, alcA and aldA genes by binding to a GC-rich region in their promoter. Plays also a role in response to carbon starvation and the control of extracellular proteases activity (By similarity); Belongs to the creA/MIG C2H2-type zinc-finger protein family [a.k.a. ANI_1_524024, An02g03830, DNA-binding protein creA]

Aspergillus niger

An11g02750 - EF hand associated family protein; Probable catabolite repression protein creC [a.k.a. ANI_1_388094, CAN33_22930, ang:ANI_1_388094]

Aspergillus oryzae

CADAORAP00000807 - Probable catabolite repression protein creC [a.k.a. AOR_1_2772154, unnamed protein product, CADAORAT00000823]

Aspergillus terreus

ATEG_05869 - Probable HECT-type ubiquitin ligase-interacting protein creD; Component of the regulatory network controlling carbon source utilization through ubiquitination and deubiquitination involving creA, creB, creC, creD and acrB. May be involved in signaling by recognizing appropriately phosphorylated substrates via its arrestin domains and then recruit a HECT-type ubiquitin ligase such as hulA, leading to ubiquitination of the substrate, providing a link between ubiquitination and phosphorylation in protein regulation and stability (By similarity) [a.k.a. creD, XP_001215047, XM_001215047]

Aspergillus terreus

ATEG_03173 - Probable ubiquitin carboxyl-terminal hydrolase creB; Ubiquitin thioesterase component of the regulatory network controlling carbon source utilization through ubiquitination and deubiquitination involving creA, creB, creC, creD and acrB. Deubiquitinates the creA catabolic repressor and the quinate permease qutD. Plays also a role in response to carbon starvation and the control of extracellular proteases activity (By similarity) [a.k.a. creB, Ubiquitin-specific-processing protease creB, Q0CT11]

Aspergillus terreus

ATEG_03161 - Probable ubiquitination network signaling protein acrB; Component of the regulatory network controlling carbon source utilization through ubiquitination and deubiquitination involving creA, creB, creC, creD and acrB. Involved in resistance to acriflavine, and required for normal growth on a range of sole carbon sources, including fructose, cellobiose, raffinose, and starch, and reduced utilization of amino acids, including GABA and beta-alanine, as sole carbon and nitrogen sources (By similarity) [a.k.a. acrB, acr2, CADATEAG00010293]

Bacteroides caccae

EDM19337.1 - Uncharacterized protein; KEGG: ypm:YP_3591 0.029 creC; putative histidine kinase sensor; COG: COG0326 Molecular chaperone, HSP90 family [a.k.a. BACCAC_03451, EDM19337, GI:149128117]

Beauveria bassiana

XP_008597888.1 - Putative catabolite repression protein creC; WD domain-containing protein [a.k.a. BBAD15_g5557, XP_008597888.1, Putative catabolite repression protein creC]

Blastomyces dermatitidis

BDCG_07816 - Catabolite repression protein creC [a.k.a. XP_002625474.1, XM_002625428.1, GeneID:8504827]

Clostridium lentocellum

Clole_3776 - Two component transcriptional regulator, winged helix family; KEGG: cst:CLOST_2557 DNA-binding response regulator in two-component regulatory system with PhoR (or CreC); PFAM: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver domain; Signal transduction response regulator, C-terminal [a.k.a. ADZ85456.1, F2JII6, GO:0003677]

Clostridium sticklandii

CLOST_1888 - DNA-binding response regulator in two-component regulatory system with PhoR (Or CreC); Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type r : regulator [a.k.a. phoB, CBH22008.1, CBH22008]

Clostridium sticklandii

CLOST_2557 - DNA-binding response regulator in two-component regulatory system with PhoR (Or CreC); Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type r : regulator [a.k.a. phoB, CBH22672.1, cst:CLOST_2557]

Coccidioides immitis

CIHG_01474 - Catabolite repression protein creC [a.k.a. XP_001247477.1, GeneID:4567816, GI:119193745]

Coccidioides posadasii

CPSG_01956 - Catabolite repression protein creC; Encoded by transcript CPC735_051490A; contains Pfam profile: PF00400: WD domain, G-beta repeat [a.k.a. XP_003065924.1, WD domain, G-beta repeat containing protein, GI:303311825]

Colletotrichum gloeosporioides

CGLO_15760 - Catabolite repression protein crec [a.k.a. UPI0002A8C185, L2GAJ3, T0JY08]

Colletotrichum higginsianum

CCF35898 - Catabolite repression protein creC [a.k.a. CH063_07589, UPI000249BDFC, CCF35898.1]

Colletotrichum orbiculare

Cob_09860 - Catabolite repression protein crec [a.k.a. ENH81453.1, UPI0002C714DD, ENH81453]

Comamonas testosteroni KF1

EED69299.1 - Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: dac:Daci_5424 sensory histidine kinase CreC [a.k.a. CtesDRAFT_PD4247, InterPro:IPR003661, Histidine kinase]

Coprinopsis cinerea

CC1G_01196 - Catabolite repression protein creC [a.k.a. XP_001833134.2, A8NEV0_COPC7, GeneID:6009628]

Cordyceps militaris

CCM_04518 - Catabolite repression protein creC [a.k.a. XP_006669729.1, G3JFF6_CORMM, cmt:CCM_04518]

Desulfarculus baarsii

Deba_0593 - Uncharacterized protein; KEGG: asa:ASA_4345 sensory histidine kinase CreC; SPTR: Q0UKW3 Putative uncharacterized protein [a.k.a. ADK83965.1, E1QEH9, GI:301638643]

Dickeya dadantii 3937

phoB - DNA-binding response regulator in two-component regulatory system with PhoR (Or CreC); PhoB is phosphorylated by the sensor-histidine kinase in response to phosphate limitation; Protein involved in transcription activator activity, two-component response regulator activity, phosphorus metabolic process and transcription [a.k.a. Dda3937_01939, ADM97343.1, E0SD26_DICD3]

Endocarpon pusillum

EPUS_08325 - Catabolite repression protein creC [a.k.a. XP_007787173.1, 19243175, 629637054]

Enterobacter asburiae LF7a

Entas_0606 - KEGG: ent:Ent638_0560 sensory histidine kinase CreC; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; HAMP linker domain; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; HAMP linker domain [a.k.a. AEN63358.1, 0004871, G2S4S9_ENTAL]

Enterobacter sp. 638

ABP59551.1 - Two component transcriptional regulator, winged helix family; TIGRFAM: phosphate regulon transcriptional regulatory protein PhoB; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: stm:STM0397 response regulator in two-component regulatory system with PhoR (or CreC), regulates pho regulon (OmpR family) [a.k.a. Ent638_0867, InterPro:IPR001789, IPR001867]

Escherichia coli ATCC8739

phoB - Response regulator in two-component regulatory system with PhoR (Or CreC); TIGRFAM: phosphate regulon transcriptional regulatory protein PhoB; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: sbo:SBO_0293 positive response regulator for pho regulon [a.k.a. BK375_27010, MS6198_03990, AUQ13_18515]

Eutypa lata

XP_007796091.1 - Putative catabolite repression protein crec protein [a.k.a. UCREL1_8221, XP_007796091.1, XM_007797900.1]

Fragaria vesca

XP_004304419.1 - Probable catabolite repression protein creC-like [a.k.a. XP_004304419.1, Probable catabolite repression protein creC-like, 101308401]

Frankia sp. EAN1pec

ABW10459.1 - PFAM: response regulator receiver; KEGG: fal:FRAAL5954 putative response regulator in two-component regulatory system with PhoR (or CreC), regulation of Pi uptake (OmpR family) (partial) [a.k.a. Franean1_1003, fre:Franean1_1003, InterPro:IPR001789]

Fusarium fujikuroi

LW93_938 - Probable WD40 repeat protein CreC [a.k.a. S0EEC0, CCT70758, CCT70758.1]

Fusarium graminearum

FGSG_08447P0 - Hypothetical protein similar to catabolite repression protein creC [a.k.a. fgr:FGSG_08447, FGSG_08447P0, FGSG_08447]

Fusarium oxysporum

FOXG_03244P0 - Catabolite repression protein creC [a.k.a. catabolite repression protein creC, FOXG_03244T0, UPI00021EA96E]

Fusarium verticillioides

FVEG_02116 - Hypothetical protein similar to catabolite repressor protein CreC [a.k.a. XP_018745369.1, FVEG_02116T0, XP_018745369]

Gaeumannomyces graminis

GGTG_00843 - Catabolite repression protein creC [a.k.a. J3NHV7_GAGT3, UPI000253869C, catabolite repression protein creC]

Geobacter sp. M18

GM18_3985 - Integral membrane sensor signal transduction histidine kinase; KEGG: geo:Geob_3646 sensory histidine kinase CreC; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein [a.k.a. ADW15403.1, ADW15403, GI:320127843]

Gloeobacter kilaueensis

GKIL_1478 - Sensory histidine kinase CreC; COG0642 [a.k.a. AGY57724.1, 553882282, sensory histidine kinase CreC]

Halothiobacillus neapolitanus

Hneap_1993 - Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; KEGG: azo:azo0703 sensory histidine kinase CreC [a.k.a. ACX96815.1, WP_012824847.1, InterPro:IPR003661]

Histoplasma capsulatum

XP_001536076.1 - Similar to CreC [a.k.a. XP_001536076.1, 154270442, HCAG_09027]

Lentisphaera araneosa

EDM27893.1 - Two-component sensor CreC; COG0642 Signal transduction histidine kinase [a.k.a. LNTAR_00790, Two-component sensor CreC, A6DKJ5]

Lentisphaera araneosa

EDM27894.1 - DNA-binding response regulator in two-component regulatory system with CreC; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [a.k.a. LNTAR_00795, EDM27894, GI:149139492]

Magnaporthe oryzae

MGG_01043 - Catabolite repression protein creC [a.k.a. G4NCS2_MAGO7, MGG_01043T0, EHA48315.1]

Magnaporthiopsis poae

MAPG_07604 - Catabolite repression protein creC [a.k.a. MAPG_07604T0, A0A0C4E543, catabolite repression protein creC]

Magnetospirillum gryphiswaldense

CDK97778.1 - DNA-binding response regulator in two-component regulatory system with PhoR (Or CreC); Evidence 2b : Function of strongly homologous gene; Product type r : regulator [a.k.a. MGMSRv2__0563, phoB, MGMSRv2_0563]

Malus domestica

XP_008369771.1 - Probable catabolite repression protein creC [a.k.a. XP_008369771.1, XM_008371549.1, GI:657956568]

Malus domestica

XP_008369772.1 - Probable catabolite repression protein creC [a.k.a. XP_008369772.1, LOC103433301, GeneID:103433301]

Malus domestica

XP_008385299.1 - Probable catabolite repression protein creC [a.k.a. XP_008385299.1, GeneID:103447871, XP_008385299]

Metarhizium acridum

MAC_03462 - Putative WD40 repeat protein CreC [a.k.a. XP_007809802.1, XP_007809802, putative WD40 repeat protein CreC]

Metarhizium robertsii

XP_007818434.1 - Putative WD40 repeat protein CreC [a.k.a. X797_000595, XP_007818434.1, A0A0A1V8H3_9HYPO]

Methylomonas methanica

Metme_3859 - KEGG: cja:CJA_1407 sensory histidine kinase CreC; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; HAMP linker domain; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; HAMP linker domain [a.k.a. AEG02213.1, F9ZXQ8, AEG02213]

Methylotenera versatilis

M301_2033 - Integral membrane sensor signal transduction histidine kinase; KEGG: reu:Reut_A0184 sensory histidine kinase CreC; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein [a.k.a. ADI30405.1, WP_013148717.1, D7DKF9]

Microbacterium sp. C448

phoB - DNA-binding response regulator in two-component regulatory system with PhoR (Or CreC); Evidence 2a:Function of homologous gene experimentally demonstrated in an other organism; Product type r:regulator [a.k.a. MIC448_810045, CDK01702.1, W0ZED8]

Moniliophthora roreri

WG66_9200 - Catabolite repression protein crec [a.k.a. XP_007846526.1, 19296546, 630184743]

Morus notabilis

XP_010107551.1 - Putative catabolite repression protein creC [a.k.a. L484_024405, XP_010107551.1, IPR001680]

Neosartorya fischeri

creA - Probable DNA-binding protein creA; Transcription regulator component of the regulatory network controlling carbon source utilization through ubiquitination and deubiquitination involving creA, creB, creC, creD and acrB. Represses the transcription of the alcR, alcA and aldA genes by binding to a GC-rich region in their promoter. Plays also a role in response to carbon starvation and the control of extracellular proteases activity (By similarity); Belongs to the creA/MIG C2H2-type zinc-finger protein family [a.k.a. NFIA_087020, XM_001260642.1, Probable DNA-binding protein creA]

Neosartorya fischeri

creB - Probable ubiquitin carboxyl-terminal hydrolase creB; Ubiquitin thioesterase component of the regulatory network controlling carbon source utilization through ubiquitination and deubiquitination involving creA, creB, creC, creD and acrB. Deubiquitinates the creA catabolic repressor and the quinate permease qutD. Plays also a role in response to carbon starvation and the control of extracellular proteases activity (By similarity) [a.k.a. NFIA_103430, Ubiquitin-specific-processing protease creB, CREB_NEOFI]

Neosartorya fischeri

Neurospora tetrasperma

XP_009854481.1 - Putative WD40 repeat protein CreC [a.k.a. NEUTE2DRAFT_160466, NEUTE1DRAFT_103979, XP_009854481.1]

Opitutus terrae

Oter_1317 - Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: mpt:Mpe_A0135 response regulator in two-component regulatory system with CreC (OmpR family) [a.k.a. ACB74602.1, WP_012374140.1, ACB74602]

Oryctolagus cuniculus

CALU - Calumenin; Involved in regulation of vitamin K-dependent carboxylation of multiple N-terminal glutamate residues. Seems to inhibit gamma-carboxylase GGCX. Binds 7 calcium ions with a low affinity (By similarity). May modulate calcium release from the sarcoplasmic reticulum; Belongs to the CREC family [a.k.a. ENSOCUT00000029125, NM_001082154.1, UPI000022FB8C]

Pantoea stewartii

phoB - DNA-binding response regulator in two-component regulatory system with PhoR (Or CreC); Two component response regulator for the phosphate regulon; PhoR phosphorylates PhoB; Derived by automated computational analysis using gene prediction method: Protein Homology [a.k.a. CKS_5044, KHD99678.1, NL54_20195]

Penicillium rubens

Pc12g09670 - Pc12g09670; Title: strong similarity to hypothetical protein involved in carbon catabolite repression creC - Aspergillus nidulans [a.k.a. PCH_Pc12g09670, XP_002557793.1, GeneID:8304262]

Pestalotiopsis fici

XP_007840926.1 - Putative catabolite repression protein creC [a.k.a. PFICI_14154, XP_007840926.1, GI:630040317]

Prunus mume

XP_008243924.1 - Probable catabolite repression protein creC [a.k.a. XP_008243924.1, 645277756, GI:645277756]

Pseudomonas fulva

Psefu_3864 - Histidine kinase; KEGG: pmy:Pmen_4119 sensory histidine kinase CreC; PFAM: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain; SMART: ATPase-like, ATP-binding domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor domain; HAMP linker domain [a.k.a. AEF23820.1, 333117306, 0004871]

Pseudomonas putida GB1

ABY96272.1 - Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: pen:PSEEN5151 two-component sensor CreC [a.k.a. PputGB1_0361, B0KJ22, WP_012270131.1]

Pseudomonas putida W619

ACA75346.1 - Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: pen:PSEEN5151 two-component sensor CreC [a.k.a. PputW619_4870, WP_012316628.1, InterPro:IPR003661]

Pseudoxanthomonas suwonensis 111

Psesu_1875 - Integral membrane sensor signal transduction histidine kinase; KEGG: xac:XAC2854 sensory histidine kinase CreC; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; histidine kinase HAMP region domain protein [a.k.a. ADV27717.1, 317465985, 0004871]

Pseudozyma flocculosa

XP_007877589.1 - Putative catabolite repression protein crec [a.k.a. XP_007877589.1, pfp:PFL1_01886, 630962362]

Pyrenophora triticirepentis

PTRG_06819 - Catabolite repression protein creC [a.k.a. EDU49739, UPI000174ABDB, B2WA11_PYRTR]

Rattus norvegicus

Rcn2 - Reticulocalbin-2; Not known. Binds calcium; Belongs to the CREC family [a.k.a. Erc55, reticulocalbin 2, NM_017132]

Salmonella enterica Typhimurium

DD95_14915 - Two-component system sensor histidine kinase CreC; Part of a two-component regulatory system with CreB or PhoB; involved in catabolic regulation; Derived by automated computational analysis using gene prediction method: Protein Homology [a.k.a. CR081_01465, CR079_09650, CR082_01045]

Schizophyllum commune

XP_003035742.1 - Similar to probable WD40 repeat protein CreC [a.k.a. SCHCODRAFT_51871, XP_003035742.1, 302692126]

Sporisorium reilianum

sr13891 - Related to WD40 repeat protein CreC [a.k.a. related to WD40 repeat protein CreC, CBQ73231.1, CBQ73231]

Stenotrophomonas maltophilia R5513

Smal_1205 - Integral membrane sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: xcc:XCC2694 sensory histidine kinase CreC [a.k.a. ACF50910.1, B4SPM3_STRM5, WP_012510477.1]

Talaromyces stipitatus

XP_002340709.1 - Catabolite repressor protein (CreC), putative; Encoded by transcript TSTA_067570A [a.k.a. TSTA_067570, XP_002340709.1, 242764103]

Tepidanaerobacter acetatoxydans

phoB - DNA-binding response regulator in two-component regulatory system with PhoR (Or CreC); Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; Product type r : regulator [a.k.a. TEPIRE1_1080, CCP25796.1, TepiRe1_1080]

Togninia minima

XP_007913445.1 - Putative catabolite repression protein crec protein [a.k.a. UCRPA7_2702, XP_007913445.1, 631237046]

Triticum urartu

TRIUR3_25504-P1 - Putative catabolite repression protein creC [a.k.a. TRIUR3_25504, Putative catabolite repression protein creC, EMS53140.1]

Triticum urartu

TRIUR3_30535-P1 - Putative catabolite repression protein creC [a.k.a. TRIUR3_30535, M8A1W1_TRIUA, TRIUR3_30535-P1]

Uncinocarpus reesii

UREG_01179 - Catabolite repression protein creC [a.k.a. XP_002541663.1, 258574963, XM_002541617.1]

Variovorax paradoxus EPS

Varpa_0028 - Integral membrane sensor signal transduction histidine kinase; KEGG: vap:Vapar_0026 sensory histidine kinase CreC; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein [a.k.a. ADU34251.1, vpe:Varpa_0028, 29714890]

Variovorax paradoxus S110

Vapar_0026 - Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: pna:Pnap_0029 sensory histidine kinase CreC [a.k.a. ACS16689.1, WP_012745191.1, InterPro:IPR003661]

Verticillium alfalfae

VDBG_07980 - Catabolite repression protein creC [a.k.a. XP_003001721.1, XP_003001721, val:VDBG_07980]

Verticillium dahliae

VDAG_05549 - Catabolite repression protein creC [a.k.a. G2X5P4, 20707012, XP_009650739]

Xanthobacter autotrophicus

Xaut_0202 - Two component transcriptional regulator, winged helix family; TIGRFAM: phosphate regulon transcriptional regulatory protein PhoB; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: bbt:BBta_1991 response regulator in two-component regulatory system with PhoR (or CreC) [a.k.a. ABS65461.1, InterPro:IPR001789, ABS65461]

Xanthomonas arboricola

IA64_06205 - Two-component system sensor histidine kinase CreC; Derived by automated computational analysis using gene prediction method: Protein Homology [a.k.a. A7D01_03015, KER84502.1, WP_065049912.1]

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