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There are several matches for 'degS'.
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1892 matches
showing page 1 of 95
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protein
1)
Escherichia coli K12
degS
- Serine endoprotease, periplasmic; A site-1 protease (S1P) that cleaves the peptide bond between 'Val-148' and 'Ser-149' in RseA. Part of a regulated intramembrane proteolysis (RIP) cascade. When heat shock or other environmental stresses disrupt protein folding in the periplasm,
DegS
senses the accumulation of unassembled outer membrane porins (OMP) and then initiates RseA (anti sigma-E factor) degradation by cleaving its periplasmic domain, making it a substrate for subsequent cleavage by RseP. This cascade ultimately leads to the sigma-E-driven expression of a variety of factors deal [...]
2)
Homo sapiens
DEGS1 - Sphingolipid delta(4)-desaturase DES1; Has sphingolipid-delta-4-desaturase activity. Converts D- erythro-sphinganine to D-erythro-sphingosine (E-sphing-4-enine). Belongs to the fatty acid desaturase type 1 family.
DEGS
subfamily.
[a.k.a. DEGS1-202, XM_017002648, E7EMA0,
DEGS
]
3)
Mus musculus
Degs1 - Sphingolipid delta(4)-desaturase DES1; Has sphingolipid-delta-4-desaturase activity. Converts D- erythro-sphinganine to D-erythro-sphingosine (E-sphing-4-enine).
[a.k.a. ENSMUSP00000048519, Des1, O09005,
Degs
]
4)
Homo sapiens
DNAJB2 - DnaJ homolog subfamily B member 2; Functions as a co-chaperone, regulating the substrate binding and activating the ATPase activity of chaperones of the HSP70/heat shock protein 70 family. In parallel, also contributes to the ubiquitin-dependent proteasomal degradation of misfolded proteins. Thereby, may regulate the aggregation and promote the functional recovery of misfolded proteins like HTT, MC4R, PRKN, RHO and SOD1 and be crucial for many biological processes. Isoform 1 which is localized to the endoplasmic reticulum membranes may specifically function in ER-associated protein
deg
[...]
[a.k.a. ENSP00000375936, ENSP00000414796, ENST00000473750.5]
5)
Homo sapiens
STAMBP - STAM-binding protein; Zinc metalloprotease that specifically cleaves 'Lys-63'- linked polyubiquitin chains. Does not cleave 'Lys-48'-linked polyubiquitin chains (By similarity). Plays a role in signal transduction for cell growth and MYC induction mediated by IL-2 and GM- CSF. Potentiates BMP (bone morphogenetic protein) signaling by antagonizing the inhibitory action of SMAD6 and SMAD7. Has a key role in regulation of cell surface receptor-mediated endocytosis and ubiquitin-dependent sorting of receptors to lysosomes. Endosomal localization of STAMBP is required for efficient EGFR
deg
[...]
[a.k.a. NP_001340896, O95630, AAI01468.1]
6)
Homo sapiens
PRNP - Major prion protein; Its primary physiological function is unclear. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May promote myelin homeostasis through acting as an agonist for ADGRG6 receptor. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro) (By similarity). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or ZN(2+) for the ascorbate-mediated GPC1 deaminase
deg
[...]
[a.k.a. Q96E70, NP_898902, Q27H91]
7)
Homo sapiens
DENND3 - DENN domain-containing protein 3; Guanine nucleotide exchange factor (GEF) activating RAB12. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB12 into its active GTP-bound form. Regulates autophagy in response to starvation through RAB12 activation. Starvation leads to ULK1/2-dependent phosphorylation of Ser-472 and Ser-490, which in turn allows recruitment of 14-3-3 adapter proteins and leads to up-regulation of GEF activity towards RAB12 (By similarity). Also plays a role in protein transport from recycling endosomes to lysosomes, regulating, for instance, the
deg
[...]
[a.k.a. UPI0001E8F5CE, DENND3-222, XM_017013241.1]
8)
Accumulibacter sp. SK01
degS
- Signal transduction histidine-protein kinase/phosphatase
DegS
.
9)
Acetoanaerobium sticklandii
degS
- Two-component sensor histidine kinase; Function of homologous gene experimentally demonstrated in an other organism; receptor.
10)
Acholeplasma palmae
degS
- Putative periplasmic serine protease
DegS
.
11)
Achromobacter sp. ATCC31444
degS
- Sensor protein
degS
.
12)
Acidithrix ferrooxidans
degS
- Signal transduction histidine-protein kinase/phosphatase
DegS
.
13)
Actinobacillus equuli
degS
- Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
14)
Actinobacillus pleuropneumoniae
degS
- Protease
DegS
precursor.
15)
Actinomyces slackii
degS
- Unannotated protein.
16)
Aeromonas bivalvium
degS
- Serine endoprotease
DegS
.
17)
Aeromonas encheleia
degS
- Unannotated protein.
18)
Aeromonas hydrophila
degS
- Periplasmic serine peptidase
DegS
; Identified by similarity to SP:P31137; match to protein family HMM PF00089; match to protein family HMM PF00595; match to protein family HMM TIGR02038.
19)
Aeromonas jandaei
degS
- Unannotated protein.
20)
Aeromonas salmonicida
degS
- Unannotated protein.
1892 matches
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