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1217 matches

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organism

protein

Homo sapiens

MBTPS2 - Membrane-bound transcription factor site-2 protease; Involved in regulated intramembrane proteolysis (RIP) that is the cleavage of membrane-spanning regulatory proteins by proteases within the plane of the membrane. It cleaves sterol-regulatory element- binding proteins (SREBPs) within the first transmembrane segment, thereby releasing the N-terminal segment with a portion of the transmembrane segment attached. Mature N-terminal fragments shuttle to the nucleus and activate gene transcription. Involved in RIP-mediated regulation of bone formation. [a.k.a. NM_015884, UPI000021249B, AAD08632.1]

Homo sapiens

MBTPS1 - Membrane-bound transcription factor site-1 protease; Serine protease that catalyzes the first step in the proteolytic activation of the sterol regulatory element-binding proteins (SREBPs). Other known substrates are BDNF, GNPTAB and ATF6. Cleaves after hydrophobic or small residues, provided that Arg or Lys is in position P4. Cleaves known substrates after Arg-Ser-Val-Leu (SERBP-2), Arg-His-Leu-Leu (ATF6), Arg-Gly-Leu-Thr (BDNF) and its own propeptide after Arg-Arg-Leu-Leu. Mediates the protein cleavage of GNPTAB into subunit alpha and beta, thereby participating in biogenesis of lysos [...] [a.k.a. URS0000D6EC63, Q24JQ2, CCDS10941.1]

Mus musculus

Mbtps2 - Membrane-bound transcription factor site-2 protease; Involved in regulated intramembrane proteolysis (RIP) that is the cleavage of membrane-spanning regulatory proteins by proteases within the plane of the membrane. It cleaves sterol-regulatory element- binding proteins (SREBPs) within the first transmembrane segment, thereby releasing the N-terminal segment with a portion of the transmembrane segment attached. Mature N-terminal fragments shuttle to the nucleus and activate gene transcription. Involved in RIP-mediated regulation of bone formation; Belongs to the peptidase M50A family. [a.k.a. Yy2, R-MMU-381119, R-MMU-381033]

Mus musculus

Mbtps1 - Membrane-bound transcription factor site-1 protease; Serine protease that catalyzes the first step in the proteolytic activation of the sterol regulatory element-binding proteins (SREBPs). Other known substrates are BDNF, GNPTAB and ATF6. Cleaves after hydrophobic or small residues, provided that Arg or Lys is in position P4. Cleaves known substrates after Arg-Ser-Val-Leu (SERBP-2), Arg-His-Leu-Leu (ATF6), Arg-Gly-Leu-Thr (BDNF) and its own propeptide after Arg-Arg-Leu-Leu. Mediates the protein cleavage of GNPTAB into subunit alpha and beta, thereby participating in biogenesis of lysos [...] [a.k.a. Q9WTZ2, NP_062683.3, R-MMU-381119]

Bacillus cereus Rock344

EEL47949.1 - Membrane-bound protease; Similar to Transglutaminase-like enzymes, putative cysteine proteases COG1305; similar to Membrane-bound protease, putative of Bacillus cereus group UniRef RepID=Q6HZK3_BACAN. [a.k.a. bcere0022_48910, EEL47949, Membrane-bound protease]

Burkholderia pseudomallei

BPSL2152 - Putative membrane-bound protease; Similar to Escherichia coli, and Escherichia coli O157:H7 protease EcfE or b0176 or z0187 or ecs0178 SWALL:ECFE_ECOLI (SWALL:P37764) (450 aa) fasta scores: E(): 1.2e-37, 39.48% id in 466 aa, and to Ralstonia solanacearum hypothetical zinc metalloprotease rsc1411 or rs05281 SWALL:YE11_RALSO (SWALL:Q8XZI4) (462 aa) fasta scores: E(): 1.2e-66, 45.25% id in 464 aa. [a.k.a. CAH36154.1, YP_108747.1, EC 3.4.24.-, Membrane-bound protease]

Gloeomargarita lithophora

APB32383.1 - Membrane-bound protease. [a.k.a. GlitD10_0082, membrane-bound protease, Membrane-bound protease]

Lactobacillus otakiensis

KRL11522.1 - Abortive infection protein. [a.k.a. FD05_GL002158, abortive infection protein, S4PQ37, Membrane-bound protease]

Lysinibacillus sphaericus

ANA45349.1 - Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. [a.k.a. A2J09_07190, lsp:Bsph_2851, hypothetical protein, Membrane-bound protease]

10)

Methylophaga lonarensis

EMR12127.1 - COG1030 Membrane-bound serine protease (ClpP class). [a.k.a. MPL1_12050, EMR12127, M7NXZ9, membrane-bound protease, Membrane-bound protease, ...]

11)

Providencia burhodogranariea

OOA_10173 - Membrane-bound protease. [a.k.a. EKT61785.1, membrane-bound protease, K8WZZ3, Membrane-bound protease]

12)

Pseudomonas plecoglossicida

RK21_05298 - Unannotated protein. [a.k.a. GCA_000688275_02308, NZ_CP010359.1, WP_041506341.1, Membrane-bound protease]

13)

Pseudomonas sp. ATCC 13867

AGI22300.1 - COG1030 Membrane-bound serine protease (ClpP class). [a.k.a. H681_02090, membrane-bound protease, AGI22300, Membrane-bound protease]

14)

Pseudomonas sp. M47T1

EIK97365.1 - COG1030 Membrane-bound serine protease (ClpP class). [a.k.a. PMM47T1_06261, EIK97365, membrane-bound protease, Membrane-bound protease]

15)

Pseudomonas sp. VLB120

AGZ33055.1 - COG1030 Membrane-bound serine protease (ClpP class). [a.k.a. PVLB_01225, psv:PVLB_01225, AGZ33055, membrane-bound protease, Membrane-bound protease, ...]

16)

Starkeya novella

Snov_1540 - KEGG: gbe:GbCGDNIH1_1332 membrane-bound protease. [a.k.a. ADH88850.1, D7A9S4, D7A9S4_STAND, membrane-bound protease, Membrane-bound protease, ...]

17)

Thermoanaerobacter kivui

AIS51548.1 - Membrane-bound protease. [a.k.a. TKV_c03430, AIS51548, 3.4.21.-, membrane-bound protease, Membrane-bound protease, ...]

18)

Vibrio scophthalmi

ANS87657.1 - Protease that cleaves its substrates preferentially near hydrophobic or aromatic amino acid residues; Belongs to the peptidase S14 family. [a.k.a. VSVS12_03957, A0A1C7FF69, Membrane-bound serine protease (ClpP class), Membrane-bound protease]

19)

Thermanaeromonas toyohensis

SMB99071.1 - Nodulation efficiency protein NfeD; InterPro IPR002810; COGs: COG1030 Membrane-bound serine protease (ClpP class); KEGG: tte:TTE0385 membrane-bound serine protease (ClpP class); SPTR: Membrane-bound serine protease (ClpP class); PFAM: protein of unknown function DUF107. [a.k.a. SAMN00808754_2729, SMB99071, A0A1W1W134_9THEO]

20)

Niastella koreensis

AEW02554.1 - Nodulation efficiency protein NfeD; PFAM: Clp protease; NfeD-like; COGs: COG1030 Membrane-bound serine protease (ClpP class); InterPro IPR002810; KEGG: tye:THEYE_A0592 membrane-bound serine protease; PFAM: Nodulation efficiency, NfeD; SPTR: Membrane-bound serine protease. [a.k.a. Niako_6330, G8TCL4, Membrane-bound serine protease (ClpP class)]

1217 matches

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