STRING: functional protein association networks

There are several matches for 'probable peptidase'.
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3605 matches

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organism

protein

Homo sapiens

KY - Kyphoscoliosis peptidase; Probable cytoskeleton-associated protease required for normal muscle growth. Involved in function, maturation and stabilization of the neuromuscular junction. May act by cleaving muscle-specific proteins such as FLNC (By similarity); Belongs to the transglutaminase-like superfamily [a.k.a. ENSP00000426777, ENST00000310263, BAC86780.1]

Homo sapiens

SERPINI1 - Neuroserpin; Serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin. May be involved in the formation or reorganization of synaptic connections as well as for synaptic plasticity in the adult nervous system. May protect neurons from cell damage by tissue-type plasminogen activator (Probable); Serpin peptidase inhibitors [a.k.a. PI12, A8K217, Serpin I1]

Homo sapiens

PREPL - Prolyl endopeptidase-like; Probable serine peptidase whose precise substrate specificity remains unclear. Does not cleave peptides after a arginine or lysine residue. May play a role in the regulation of synaptic vesiscle exocytosis [a.k.a. KIAA0436, PREPL-009, NM_001171617.1]

Homo sapiens

SPINK7 - Serine protease inhibitor Kazal-type 7; Probable serine protease inhibitor; Serine peptidase inhibitors, Kazal type [a.k.a. ECG2, UNQ745/PRO1474, ENSP00000274565]

Homo sapiens

SPINK8 - Serine protease inhibitor Kazal-type 8; Probable serine protease inhibitor; Serine peptidase inhibitors, Kazal type [a.k.a. OTTHUMP00000210747, NP_001073994, ENST00000434006]

Homo sapiens

SERPINE3 - Serpin E3; Probable serine protease inhibitor; Serpin peptidase inhibitors [a.k.a. 647174, Hs.685891, OTTHUMT00000381482]

Homo sapiens

PRTN3 - Myeloblastin; Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro). By cleaving and activating receptor F2RL1/PAR-2, enhances endothelial cell barrier function and thus vascular integrity during neutrophil transendothelial migration. May play a role in neutrophil transendothelial migration, probably when associated with CD177; Belongs to the peptidase S1 family. Elastase subfamily [a.k.a. MBN, P24158, ENSG00000196415]

Homo sapiens

SERPINB11 - Serpin B11; Has no serine protease inhibitory activity, probably due to mutations in the scaffold impairing conformational change; Serpin peptidase inhibitors [a.k.a. Q96P13, NM_001291278, ENSG00000206072]

Homo sapiens

PRSS50 - Probable threonine protease PRSS50; May be involved in proteolysis through its threonine endopeptidase activity; Belongs to the peptidase S1 family [a.k.a. TSP50, CT20, OTTHUMG00000164067]

10)

Homo sapiens

ENPEP - Glutamyl aminopeptidase; Appears to have a role in the catabolic pathway of the renin-angiotensin system. Probably plays a role in regulating growth and differentiation of early B-lineage cells; Belongs to the peptidase M1 family [a.k.a. 4KX9, Q07075, CD249]

11)

Homo sapiens

DPEP3 - Dipeptidase 3; Probable metalloprotease which hydrolyzes cystinyl-bis- glycine. May be involved in meiosis (By similarity); Belongs to the metallo-dependent hydrolases superfamily. Peptidase M19 family [a.k.a. UNQ834/PRO1772, EAW83198.1, OTTHUMT00000268875]

12)

Homo sapiens

PRSS37 - Probable inactive serine protease 37; Plays a role in male fertility (By similarity). May have a role in sperm migration or binding to zona-intact eggs (By similarity). Involved in the activation of the proacrosin/acrosin system; Belongs to the peptidase S1 family [a.k.a. TRYX2, PRSS37-002, Probable inactive serine protease 37]

13)

Homo sapiens

TMPRSS3 - Transmembrane protease serine 3; Probable serine protease that plays a role in hearing. Acts as a permissive factor for cochlear hair cell survival and activation at the onset of hearing and is required for saccular hair cell survival (By similarity). Activates ENaC (in vitro); Belongs to the peptidase S1 family [a.k.a. ECHOS1, UNQ323/PRO382, TADG12]

14)

Homo sapiens

ASTL - Astacin-like metalloendopeptidase; Oocyte-specific oolemmal receptor involved in sperm and egg adhesion and fertilization. Plays a role in the polyspermy inhibition. Probably acts as a protease for the post-fertilization cleavage of ZP2. Cleaves the sperm-binding ZP2 at the surface of the zona pellucida after fertilization and cortical granule exocytosis, rendering the zona pellucida unable to support further sperm binding (By similarity); Belongs to the peptidase M12A family [a.k.a. Ovastacin, ASTL_HUMAN, uc010yui.2]

15)

Homo sapiens

SPINK5 - Serine protease inhibitor Kazal-type 5; Serine protease inhibitor, probably important for the anti-inflammatory and/or antimicrobial protection of mucous epithelia. Contribute to the integrity and protective barrier function of the skin by regulating the activity of defense- activating and desquamation-involved proteases. Inhibits KLK5, it's major target, in a pH-dependent manner. Inhibits KLK7, KLK14 CASP14, and trypsin; Serine peptidase inhibitors, Kazal type [a.k.a. CCDS43382.1, OTTHUMT00000259220, E7EWP9]

16)

Mus musculus

Ky - Kyphoscoliosis peptidase; Probable cytoskeleton-associated protease required for normal muscle growth. Involved in function, maturation and stabilization of the neuromuscular junction. May act by cleaving muscle-specific proteins such as FLNC [a.k.a. CD1, D9Mgc44e, OTTMUST00000124158]

17)

Mus musculus

Prepl - Prolyl endopeptidase-like; Probable serine peptidase whose precise substrate specificity remains unclear. Does not cleave peptides after a arginine or lysine residue. May play a role in the regulation of synaptic vesiscle exocytosis [a.k.a. Kiaa0436, ENSMUST00000171795, NP_001157096]

18)

Mus musculus

Pga5 - Pepsin A-5; Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent (By similarity). May play a role as a specialized neonatal digestive enzyme (Probable); Belongs to the peptidase A1 family [a.k.a. Pepf, uc008gqp.2, Pepsin A-5]

19)

Mus musculus

Prtn3 - Myeloblastin; Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro). By cleaving and activating receptor F2RL1/PAR-2, enhances endothelial cell barrier function and thus vascular integrity during neutrophil transendothelial migration. May play a role in neutrophil transendothelial migration, probably when associated with CD177; Belongs to the peptidase S1 family. Elastase subfamily [a.k.a. CCDS23993.1, NP_035308.2, ENSMUSG00000057729]

20)

Mus musculus

Phex - Metalloendopeptidase homolog PEX; Probably involved in bone and dentin mineralization and renal phosphate reabsorption; Belongs to the peptidase M13 family [a.k.a. Hyp, Pex, UPI0000F22433]

3605 matches

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