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BEAF-32 - Boundary element-associated factor of 32kD (BEAF-32) is a DNA-binding protein with binding sites near transcription start sites. BEAF-32 roles include chromatin domain insulator function, gene regulation and genome organization
[a.k.a. FBgn0015602, Dmel_CG10159, CG10159]
E(z) - Histone-lysine N-methyltransferase E(z); Polycomb group (PcG) protein. Catalytic subunit of the Esc/E(z) complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. While PcG proteins are generally required to maintain the transcriptionally repressive state of homeotic genes throughout development, this protein is specifically required during the first 6 hours of embryogenesis to establish the repressed state. The Esc/E(z) complex is necessary but not sufficient for the repression of homeotic target genes, suggesting [...]
[a.k.a. FBgn0000629, CG6502, KMT6]
© STRING Consortium 2020
SIB - Swiss Institute of Bioinformatics
CPR - Novo Nordisk Foundation Center Protein Research
EMBL - European Molecular Biology Laboratory
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