Organism Overview: Buchnera aphidicola


 
gidA protein networkhttps://string-db.org/network/261317.BCTU_001Glucose inhibited division protein A; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s( [...]
gyrB protein networkhttps://string-db.org/network/261317.BCTU_002DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in a [...]
dnaN protein networkhttps://string-db.org/network/261317.BCTU_003DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loadi [...]
dnaA protein networkhttps://string-db.org/network/261317.BCTU_004Chromosomal replication initiator protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-st [...]
rpmH protein networkhttps://string-db.org/network/261317.BCTU_00550S ribosomal protein L34; RpmH; Belongs to the bacterial ribosomal protein bL34 family.
rnpA protein networkhttps://string-db.org/network/261317.BCTU_006Protein component of ribonuclease P; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S R [...]
yidC protein networkhttps://string-db.org/network/261317.BCTU_007Putative inner membrane protein translocase component; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integ [...]
thdF protein networkhttps://string-db.org/network/261317.BCTU_008GTP-binding protein; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, form [...]
groES protein networkhttps://string-db.org/network/261317.BCTU_010Chaperone Hsp10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
groEL protein networkhttps://string-db.org/network/261317.BCTU_011Chaperone Hsp60; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
efp protein networkhttps://string-db.org/network/261317.BCTU_012Elongation factor P; Efp.
dnaC protein networkhttps://string-db.org/network/261317.BCTU_013DNA replication protein; DnaC.
yhhF protein networkhttps://string-db.org/network/261317.BCTU_014Putative methyltransferase; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family.
ftsY protein networkhttps://string-db.org/network/261317.BCTU_015Signal recognition particle receptor; FtsY.
rpoH protein networkhttps://string-db.org/network/261317.BCTU_016RNA polymerase sigma-32 factor; RpoH; Belongs to the sigma-70 factor family.
metE protein networkhttps://string-db.org/network/261317.BCTU_0175-methyltetrahydropteroyltriglutamate- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; [...]
rpoC protein networkhttps://string-db.org/network/261317.BCTU_018DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rpoB protein networkhttps://string-db.org/network/261317.BCTU_019DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rplL protein networkhttps://string-db.org/network/261317.BCTU_02050S ribosomal protein L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacte [...]
rplJ protein networkhttps://string-db.org/network/261317.BCTU_02150S ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal prot [...]
rplA protein networkhttps://string-db.org/network/261317.BCTU_02250S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.
rplK protein networkhttps://string-db.org/network/261317.BCTU_02350S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
nusG protein networkhttps://string-db.org/network/261317.BCTU_024Transcription antitermination protein; Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA [...]
secE protein networkhttps://string-db.org/network/261317.BCTU_025Preprotein translocase subunit SecE; SecE; Belongs to the SecE/SEC61-gamma family.
metF protein networkhttps://string-db.org/network/261317.BCTU_0305,10-methylenetetrahydrofolate reductase; MetF; Belongs to the methylenetetrahydrofolate reductase family.
argG protein networkhttps://string-db.org/network/261317.BCTU_031Argininosuccinate synthase; ArgG; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
argH protein networkhttps://string-db.org/network/261317.BCTU_032Argininosuccinate lyase; ArgH.
rpoD protein networkhttps://string-db.org/network/261317.BCTU_033RNA polymerase sigma-70 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the pri [...]
dnaG protein networkhttps://string-db.org/network/261317.BCTU_034DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Belongs to the DnaG primase family.
rpsU protein networkhttps://string-db.org/network/261317.BCTU_03530S ribosomal protein S21; RpsU; Belongs to the bacterial ribosomal protein bS21 family.
gcp protein networkhttps://string-db.org/network/261317.BCTU_036Putative O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is invo [...]
cca protein networkhttps://string-db.org/network/261317.BCTU_037tRNA nucleotidyltransferase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order [...]
lig protein networkhttps://string-db.org/network/261317.BCTU_038DNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy sourc [...]
gltX protein networkhttps://string-db.org/network/261317.BCTU_041glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end [...]
fliF protein networkhttps://string-db.org/network/261317.BCTU_042Flagellar basal-body MS-ring and collar protein; FliF.
fliG protein networkhttps://string-db.org/network/261317.BCTU_043Flagellar motor switch protein; FliG.
fliH protein networkhttps://string-db.org/network/261317.BCTU_044Soluble component of the flagellar export system; FliH.
fliI protein networkhttps://string-db.org/network/261317.BCTU_045Flagellum-specific ATP synthase; FliI.
fliJ protein networkhttps://string-db.org/network/261317.BCTU_046Soluble component of the flagellar export system; FliJ.
fliM protein networkhttps://string-db.org/network/261317.BCTU_047Flagellar motor switch protein, C-ring protein; FliM.
fliO protein networkhttps://string-db.org/network/261317.BCTU_048Type III protein export, membrane component; FliO.
fliP protein networkhttps://string-db.org/network/261317.BCTU_049Type III protein export, membrane component; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family.
fliQ protein networkhttps://string-db.org/network/261317.BCTU_050Type III protein export, membrane component; Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family.
fliR protein networkhttps://string-db.org/network/261317.BCTU_051Type III protein export, membrane component; FliR.
rpmG protein networkhttps://string-db.org/network/261317.BCTU_05250S ribosomal protein L33; RpmG; Belongs to the bacterial ribosomal protein bL33 family.
rpmB protein networkhttps://string-db.org/network/261317.BCTU_05350S ribosomal protein L28; RpmB; Belongs to the bacterial ribosomal protein bL28 family.
ppa protein networkhttps://string-db.org/network/261317.BCTU_054Inorganic pyrophosphatase; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.
pmbA protein networkhttps://string-db.org/network/261317.BCTU_055Putative modulator of DNA gyrase; PmbA.
fabB protein networkhttps://string-db.org/network/261317.BCTU_0573-oxoacyl-[acyl-carrier-protein] synthase I; YraL; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
talA protein networkhttps://string-db.org/network/261317.BCTU_058Transaldolase A; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 1 subfamily.
tktB protein networkhttps://string-db.org/network/261317.BCTU_059Transketolase; TktB; Belongs to the transketolase family.
dapE protein networkhttps://string-db.org/network/261317.BCTU_060Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in [...]
dapA protein networkhttps://string-db.org/network/261317.BCTU_061Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
aroc protein networkhttps://string-db.org/network/261317.BCTU_062Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch poin [...]
yfcn protein networkhttps://string-db.org/network/261317.BCTU_063Putative phage-like protein; Yfcn.
hisG protein networkhttps://string-db.org/network/261317.BCTU_064Histidinol-phosphatase/imidazoleglycerol- phosphate dehydratase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial ro [...]
hisD protein networkhttps://string-db.org/network/261317.BCTU_065Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
hisC protein networkhttps://string-db.org/network/261317.BCTU_066Histidinol-phosphate aminotransferase; HisC; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
hisB protein networkhttps://string-db.org/network/261317.BCTU_067Imidazole glycerol-phosphate dehydratase; HisB; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.
hisH protein networkhttps://string-db.org/network/261317.BCTU_068Imidazole glycerol-phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and am [...]
hisA protein networkhttps://string-db.org/network/261317.BCTU_069Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; HisA.
hisF protein networkhttps://string-db.org/network/261317.BCTU_070Imidazole glycerol-phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and [...]
hisI protein networkhttps://string-db.org/network/261317.BCTU_071phosphoribosyl-AMP cyclohydrolase / phosphoribosyl-ATP pyrophosphohydrolase; HisI; In the N-terminal section; belongs to the PRA-CH family.
gnd protein networkhttps://string-db.org/network/261317.BCTU_0726-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
metG protein networkhttps://string-db.org/network/261317.BCTU_073methionyl-tRNA synthetase; MetG; Belongs to the class-I aminoacyl-tRNA synthetase family.
mesJ protein networkhttps://string-db.org/network/261317.BCTU_074tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is [...]
nth protein networkhttps://string-db.org/network/261317.BCTU_076Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- [...]
tyrS protein networkhttps://string-db.org/network/261317.BCTU_077tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of [...]
sufA protein networkhttps://string-db.org/network/261317.BCTU_078Fe-S assembly scaffold protein; SufA; Belongs to the HesB/IscA family.
aroH protein networkhttps://string-db.org/network/261317.BCTU_079Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate [...]
thrS protein networkhttps://string-db.org/network/261317.BCTU_080threonyl-tRNA synthetase; ThrS; Belongs to the class-II aminoacyl-tRNA synthetase family.
infc protein networkhttps://string-db.org/network/261317.BCTU_081Initiation factor IF-3; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the av [...]
rpmI protein networkhttps://string-db.org/network/261317.BCTU_08250S ribosomal protein L35; RpmI; Belongs to the bacterial ribosomal protein bL35 family.
rplt protein networkhttps://string-db.org/network/261317.BCTU_08350S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing func [...]
pheS protein networkhttps://string-db.org/network/261317.BCTU_084phenylalanyl-tRNA synthetase, alpha subunit; PheS; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.
phet protein networkhttps://string-db.org/network/261317.BCTU_085phenylalanyl-tRNA synthetase, beta subunit; Phet; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
himA protein networkhttps://string-db.org/network/261317.BCTU_086Integration host factor alpha subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in tra [...]
glyS protein networkhttps://string-db.org/network/261317.BCTU_087glycyl-tRNA synthetase, beta subunit; GlyS.
glyQ protein networkhttps://string-db.org/network/261317.BCTU_088glycyl-tRNA synthetase, alpha subunit; GlyQ.
nfo protein networkhttps://string-db.org/network/261317.BCTU_089Endonuclease IV with intrinsic 3'-5' exonuclease activity; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new [...]
rplY protein networkhttps://string-db.org/network/261317.BCTU_09050S ribosomal protein L25; RplY; Belongs to the bacterial ribosomal protein bL25 family.
yabl protein networkhttps://string-db.org/network/261317.BCTU_091Hypothetical protein; Yabl.
ksgA protein networkhttps://string-db.org/network/261317.BCTU_092Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a c [...]
apaH protein networkhttps://string-db.org/network/261317.BCTU_093Diadenosine tetraphosphatase; ApaH.
carB protein networkhttps://string-db.org/network/261317.BCTU_094Carbamoyl-phosphate synthase large chain; CarB; Belongs to the CarB family.
carA protein networkhttps://string-db.org/network/261317.BCTU_095Carbamoyl-phosphate synthase small chain; CarA; Belongs to the CarA family.
dapB protein networkhttps://string-db.org/network/261317.BCTU_096Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family.
ileS protein networkhttps://string-db.org/network/261317.BCTU_097isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such e [...]
rpsT protein networkhttps://string-db.org/network/261317.BCTU_09830S ribosomal protein S20; Binds directly to 16S ribosomal RNA.
dnaJ protein networkhttps://string-db.org/network/261317.BCTU_099Chaperone Hsp40; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonom [...]
dnaK protein networkhttps://string-db.org/network/261317.BCTU_100Chaperone Hsp70; Acts as a chaperone; Belongs to the heat shock protein 70 family.
nuoA protein networkhttps://string-db.org/network/261317.BCTU_101NADH dehydrogenase I chain A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain.
nuoB protein networkhttps://string-db.org/network/261317.BCTU_102NADH dehydrogenase I chain B; NuoB; Belongs to the complex I 20 kDa subunit family.
nuocD protein networkhttps://string-db.org/network/261317.BCTU_103NADH dehydrogenase I chain C; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in t [...]
nuoE protein networkhttps://string-db.org/network/261317.BCTU_104NADH dehydrogenase I chain E; NuoE.
nuoF protein networkhttps://string-db.org/network/261317.BCTU_105NADH dehydrogenase I chain F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.
nuoG protein networkhttps://string-db.org/network/261317.BCTU_106NADH dehydrogenase I chain G; NuoG.
nuoH protein networkhttps://string-db.org/network/261317.BCTU_107NADH dehydrogenase I chain H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in t [...]
nuoI protein networkhttps://string-db.org/network/261317.BCTU_108NADH dehydrogenase I chain I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in t [...]
nuoJ protein networkhttps://string-db.org/network/261317.BCTU_109NADH dehydrogenase I chain J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation [...]
nuoK protein networkhttps://string-db.org/network/261317.BCTU_110NADH dehydrogenase I chain K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in t [...]
nuoL protein networkhttps://string-db.org/network/261317.BCTU_111NADH dehydrogenase I chain L; NuoL.
nuoM protein networkhttps://string-db.org/network/261317.BCTU_112NADH dehydrogenase I chain M; NuoM.
nuoN protein networkhttps://string-db.org/network/261317.BCTU_113NADH dehydrogenase I chain N; NuoN.
prsA protein networkhttps://string-db.org/network/261317.BCTU_114Phosphoribosylpyrophosphate synthase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1- [...]
prfA protein networkhttps://string-db.org/network/261317.BCTU_115Peptide chain release factor 1; PrfA.
hemK protein networkhttps://string-db.org/network/261317.BCTU_116N5-glutamine methyltransferase, release factors activity modulator; HemK.
ychA protein networkhttps://string-db.org/network/261317.BCTU_117Hypothetical protein; YchA.
ackA protein networkhttps://string-db.org/network/261317.BCTU_118Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
pta protein networkhttps://string-db.org/network/261317.BCTU_119Phosphate acetyltransferase; Pta.
gyrA protein networkhttps://string-db.org/network/261317.BCTU_120DNA gyrase, subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in [...]
ahpc protein networkhttps://string-db.org/network/261317.BCTU_121Alkyl hydroperoxide reductase; Ahpc.
ung protein networkhttps://string-db.org/network/261317.BCTU_122uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
ydhD protein networkhttps://string-db.org/network/261317.BCTU_124Hypothetical protein; YdhD; Belongs to the glutaredoxin family. Monothiol subfamily.
rnt protein networkhttps://string-db.org/network/261317.BCTU_125Exoribonuclease T; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal A [...]
pth protein networkhttps://string-db.org/network/261317.BCTU_126peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
ychF protein networkhttps://string-db.org/network/261317.BCTU_127GTP-binding protein; YchF.
thrc protein networkhttps://string-db.org/network/261317.BCTU_128Threonine synthase; Thrc.
thrB protein networkhttps://string-db.org/network/261317.BCTU_129Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
thrA protein networkhttps://string-db.org/network/261317.BCTU_130Aspartokinase I / homoserine dehydrogenase I; ThrA; In the C-terminal section; belongs to the homoserine dehydrogenase family.
dksA protein networkhttps://string-db.org/network/261317.BCTU_132DnaK suppressor protein; PcnB.
truA protein networkhttps://string-db.org/network/261317.BCTU_133Pseudouridylate synthase I; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
secA protein networkhttps://string-db.org/network/261317.BCTU_134Preprotein translocase subunit (ATPase); Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP [...]
aceE protein networkhttps://string-db.org/network/261317.BCTU_135Pyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
aceF protein networkhttps://string-db.org/network/261317.BCTU_136Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase).
lpdA protein networkhttps://string-db.org/network/261317.BCTU_137Pyruvate and 2-oxoglutarate dehydrogenase E3 component (dihydrolipoamide dehydrogenase); LpdA.
yadr protein networkhttps://string-db.org/network/261317.BCTU_138Hypothetical protein, hesB/yadR/yfhF family; Yadr; Belongs to the HesB/IscA family.
ftsZ protein networkhttps://string-db.org/network/261317.BCTU_139Cytoskeletal cell division protein; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls [...]
ftsA protein networkhttps://string-db.org/network/261317.BCTU_140ATP-binding cell division protein; FtsA.
yabc protein networkhttps://string-db.org/network/261317.BCTU_141S-adenosyl-dependent methyl transferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
ilvH protein networkhttps://string-db.org/network/261317.BCTU_142Acetolactate synthase III, small subunit; IlvH.
ilvI protein networkhttps://string-db.org/network/261317.BCTU_143Acetolactate synthase III, large subunit; IlvI.
dapD protein networkhttps://string-db.org/network/261317.BCTU_1442,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; DapD.
map protein networkhttps://string-db.org/network/261317.BCTU_145Methionine aminopeptidase; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharg [...]
rpsB protein networkhttps://string-db.org/network/261317.BCTU_14630S ribosomal protein S2; RpsB; Belongs to the universal ribosomal protein uS2 family.
tsf protein networkhttps://string-db.org/network/261317.BCTU_147Elongation factor Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the [...]
frr protein networkhttps://string-db.org/network/261317.BCTU_148Ribosome recycling factor; Frr.
yaeT protein networkhttps://string-db.org/network/261317.BCTU_149Outer membrane protein precursor; YaeT.
fabZ protein networkhttps://string-db.org/network/261317.BCTU_150(3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase; FabZ.
dnaE protein networkhttps://string-db.org/network/261317.BCTU_151DNA polymerase III, alpha subunit; DnaE.
proS protein networkhttps://string-db.org/network/261317.BCTU_152prolyl-tRNA synthetase; ProS.
flhB protein networkhttps://string-db.org/network/261317.BCTU_153Type III protein export, membrane component; FlhB.
flhA protein networkhttps://string-db.org/network/261317.BCTU_154Type III protein export, membrane component; FlhA.
argS protein networkhttps://string-db.org/network/261317.BCTU_155arginyl-tRNA synthetase; ArgS; Belongs to the class-I aminoacyl-tRNA synthetase family.
gloB protein networkhttps://string-db.org/network/261317.BCTU_159Probable hydroxyacylglutathione hydrolase; GloB; Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.
rnhA protein networkhttps://string-db.org/network/261317.BCTU_160Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
dnaQ protein networkhttps://string-db.org/network/261317.BCTU_161DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing func [...]
grpE1 protein networkhttps://string-db.org/network/261317.BCTU_163Hsp 24 nucleotide exchange factor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and Gr [...]
smpB protein networkhttps://string-db.org/network/261317.BCTU_164tmRNA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. t [...]
tadA protein networkhttps://string-db.org/network/261317.BCTU_165tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
acpS protein networkhttps://string-db.org/network/261317.BCTU_166Holo-[acyl-carrier protein] synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family.
era protein networkhttps://string-db.org/network/261317.BCTU_167GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in [...]
rnc protein networkhttps://string-db.org/network/261317.BCTU_168Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some m [...]
lepB protein networkhttps://string-db.org/network/261317.BCTU_169Signal peptidase I; LepB; Belongs to the peptidase S26 family.
lepA protein networkhttps://string-db.org/network/261317.BCTU_170GTP-binding elongation factor; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one [...]
trmU protein networkhttps://string-db.org/network/261317.BCTU_171tRNA (5-methylaminomethyl-2-thiouridylate) methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of [...]
fabI protein networkhttps://string-db.org/network/261317.BCTU_172NADH-dependent enoyl-ACP reductase; FabI.
rnb protein networkhttps://string-db.org/network/261317.BCTU_173Exoribonuclease II; Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction.
ychE protein networkhttps://string-db.org/network/261317.BCTU_174Putative channel protein; YchE.
lipB protein networkhttps://string-db.org/network/261317.BCTU_175Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can al [...]
lipA protein networkhttps://string-db.org/network/261317.BCTU_176Lipoic acid synthetase (FeS enzyme); Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-depe [...]
sppA protein networkhttps://string-db.org/network/261317.BCTU_177Protease IV, a signal peptide peptidase; SppA.
yciA protein networkhttps://string-db.org/network/261317.BCTU_178Putative acyl-CoA thioester hydrolase; YciA.
ycic protein networkhttps://string-db.org/network/261317.BCTU_179Hypothetical protein; Ycic.
trpA protein networkhttps://string-db.org/network/261317.BCTU_180Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
trpB protein networkhttps://string-db.org/network/261317.BCTU_181Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
trpc protein networkhttps://string-db.org/network/261317.BCTU_182Indole-3-glycerol phosphate synthase (IGPS) / N-(5'-phospho-ribosyl)anthranilate isomerase (PRAI); Trpc; Belongs to the TrpF family.
trpD protein networkhttps://string-db.org/network/261317.BCTU_183Anthranilate synthase component II; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate ( [...]
yedA protein networkhttps://string-db.org/network/261317.BCTU_184Putative transmembrane protein; YedA.
yciL protein networkhttps://string-db.org/network/261317.BCTU_185Ribosomal large subunit pseudouridine synthase B; YciL; Belongs to the pseudouridine synthase RsuA family.
suhB protein networkhttps://string-db.org/network/261317.BCTU_186Inositol monophosphatase; SuhB.
yfgB protein networkhttps://string-db.org/network/261317.BCTU_187Putative pyruvate formate lyase activating enzyme; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a cruci [...]
hisS protein networkhttps://string-db.org/network/261317.BCTU_188histidyl-tRNA synthetase; HisS; Belongs to the class-II aminoacyl-tRNA synthetase family.
glyA protein networkhttps://string-db.org/network/261317.BCTU_189Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major s [...]
mfd protein networkhttps://string-db.org/network/261317.BCTU_190Transcription-repair coupling factor; Mfd.
gapA protein networkhttps://string-db.org/network/261317.BCTU_191Glyceraldehyde 3-phosphate dehydrogenase; GapA; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
fldA protein networkhttps://string-db.org/network/261317.BCTU_192Flavodoxin; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family.
ybgI protein networkhttps://string-db.org/network/261317.BCTU_193Putative hydrolase oxidase; YbgI.
sucA protein networkhttps://string-db.org/network/261317.BCTU_1942-oxoglutarate dehydrogenase E1 component; SucA.
sucB protein networkhttps://string-db.org/network/261317.BCTU_1952-oxoglutarate dehydrogenase E2 component; SucB.
gpmA protein networkhttps://string-db.org/network/261317.BCTU_196Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.
pfkA protein networkhttps://string-db.org/network/261317.BCTU_1976-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
tpiA protein networkhttps://string-db.org/network/261317.BCTU_198Triose phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to th [...]
himD protein networkhttps://string-db.org/network/261317.BCTU_199Integration host factor beta subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in tran [...]
rpsA protein networkhttps://string-db.org/network/261317.BCTU_20030S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.
aroA protein networkhttps://string-db.org/network/261317.BCTU_2013-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl [...]
serC protein networkhttps://string-db.org/network/261317.BCTU_202Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belon [...]
serS protein networkhttps://string-db.org/network/261317.BCTU_203seryl-tRNA synthetase; SerS.
trxB protein networkhttps://string-db.org/network/261317.BCTU_204Thioredoxin reductase; TrxB.
infA protein networkhttps://string-db.org/network/261317.BCTU_205Initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) s [...]
aspS protein networkhttps://string-db.org/network/261317.BCTU_206aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor [...]
yebC protein networkhttps://string-db.org/network/261317.BCTU_207Hypothetical protein; YebC.
pykA protein networkhttps://string-db.org/network/261317.BCTU_208Pyruvate kinase; PykA; Belongs to the pyruvate kinase family.
htpX protein networkhttps://string-db.org/network/261317.BCTU_209Heat shock protein, peptidase family M48; HtpX.
yeaZ protein networkhttps://string-db.org/network/261317.BCTU_210Putative glycoprotein endopeptidase; YeaZ.
minE protein networkhttps://string-db.org/network/261317.BCTU_211Cell division topological specificity factor; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures c [...]
minD protein networkhttps://string-db.org/network/261317.BCTU_212Septum site-determining protein; MinD.
minc protein networkhttps://string-db.org/network/261317.BCTU_213Cell division inhibitor; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed [...]
rsmc protein networkhttps://string-db.org/network/261317.BCTU_21416S RNA G1207 methylase; Rsmc.
ompA protein networkhttps://string-db.org/network/261317.BCTU_218Outer membrane protein A precursor; OmpA; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
mviN protein networkhttps://string-db.org/network/261317.BCTU_219Virulence factor MviN-like protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.
flgB protein networkhttps://string-db.org/network/261317.BCTU_220Flagellar basal-body rod protein; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
flgC protein networkhttps://string-db.org/network/261317.BCTU_221Flagellar basal-body rod protein; FlgC.
flgF protein networkhttps://string-db.org/network/261317.BCTU_222Flagellar basal-body rod protein; FlgF.
flgG protein networkhttps://string-db.org/network/261317.BCTU_223Flagellar basal-body rod protein; FlgG; Belongs to the flagella basal body rod proteins family.
flgH protein networkhttps://string-db.org/network/261317.BCTU_224Flagellar L-ring protein precursor; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
flgI protein networkhttps://string-db.org/network/261317.BCTU_225Flagellar P-ring protein precursor; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
rluC protein networkhttps://string-db.org/network/261317.BCTU_226Ribosomal large subunit pseudouridine synthase C; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
rpmF protein networkhttps://string-db.org/network/261317.BCTU_22750S ribosomal protein L32; RpmF; Belongs to the bacterial ribosomal protein bL32 family.
fabD protein networkhttps://string-db.org/network/261317.BCTU_228Malonyl CoA-acyl carrier protein transacylase; FabD.
fabG protein networkhttps://string-db.org/network/261317.BCTU_2293-oxoacyl-[acyl-carrier protein] reductase; FabG.
acpP protein networkhttps://string-db.org/network/261317.BCTU_230Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family.
holB protein networkhttps://string-db.org/network/261317.BCTU_231DNA polymerase III, delta subunit; HolB.
ycfH protein networkhttps://string-db.org/network/261317.BCTU_232Putative deoxyribonuclease; YcfH.
ycfF protein networkhttps://string-db.org/network/261317.BCTU_233Hypothetical protein; YcfF.
asnS protein networkhttps://string-db.org/network/261317.BCTU_234asparaginyl-tRNA synthetase; AsnS.
yceA protein networkhttps://string-db.org/network/261317.BCTU_236UPF0176 protein BCTU_236; Uup; Belongs to the UPF0176 family.
valS protein networkhttps://string-db.org/network/261317.BCTU_237valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors [...]
pepA protein networkhttps://string-db.org/network/261317.BCTU_238Aminopeptidase A; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
argF protein networkhttps://string-db.org/network/261317.BCTU_239Ornithine carbamoyltransferase chain F; ArgF.
yhar protein networkhttps://string-db.org/network/261317.BCTU_240Hypothetical protein; Yhar.
deaD protein networkhttps://string-db.org/network/261317.BCTU_241ATP-dependent RNA helicase; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.
pnp protein networkhttps://string-db.org/network/261317.BCTU_242Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
rpsO protein networkhttps://string-db.org/network/261317.BCTU_24330S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
truB protein networkhttps://string-db.org/network/261317.BCTU_244tRNA pseudouridine 55 synthetase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamil [...]
rbfA protein networkhttps://string-db.org/network/261317.BCTU_245Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but n [...]
infB protein networkhttps://string-db.org/network/261317.BCTU_246Initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribo [...]
nusA protein networkhttps://string-db.org/network/261317.BCTU_247Transcription elongation factor; Participates in both transcription termination and antitermination.
hflB protein networkhttps://string-db.org/network/261317.BCTU_249ATP-dependent protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Be [...]
ftsJ protein networkhttps://string-db.org/network/261317.BCTU_250Ribosomal methytransferase; FtsJ.
greA protein networkhttps://string-db.org/network/261317.BCTU_251Transcription elongation factor; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a [...]
yrba protein networkhttps://string-db.org/network/261317.BCTU_252Putative transcriptional regulator; Yrba.
rpmA protein networkhttps://string-db.org/network/261317.BCTU_25350S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
rplU protein networkhttps://string-db.org/network/261317.BCTU_25450S ribosomal protein L27; RplU.
yhbZ protein networkhttps://string-db.org/network/261317.BCTU_255GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role [...]
rpsI protein networkhttps://string-db.org/network/261317.BCTU_25630S ribosomal protein S9; RpsI; Belongs to the universal ribosomal protein uS9 family.
rplM protein networkhttps://string-db.org/network/261317.BCTU_25750S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages [...]
pheA protein networkhttps://string-db.org/network/261317.BCTU_258Chorismate mutase; PheA.
ffh protein networkhttps://string-db.org/network/261317.BCTU_259Protein component of signal recognition particle (SRP); Ffh.
rpsP protein networkhttps://string-db.org/network/261317.BCTU_26030S ribosomal protein S16; RpsP; Belongs to the bacterial ribosomal protein bS16 family.
rimM protein networkhttps://string-db.org/network/261317.BCTU_26116S rRNA-processing protein; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Ess [...]
trmD protein networkhttps://string-db.org/network/261317.BCTU_262tRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family.
rplS protein networkhttps://string-db.org/network/261317.BCTU_26350S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
tldD protein networkhttps://string-db.org/network/261317.BCTU_264Predicted Zn-dependent protease; TldD.
aroQ protein networkhttps://string-db.org/network/261317.BCTU_2653-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
rluD protein networkhttps://string-db.org/network/261317.BCTU_266Ribosomal large subunit pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family.
alaS protein networkhttps://string-db.org/network/261317.BCTU_267alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRN [...]
csrA protein networkhttps://string-db.org/network/261317.BCTU_268Carbon storage regulator; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid g [...]
yggJ protein networkhttps://string-db.org/network/261317.BCTU_27116S rRNA methyltransferase; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.
zapA protein networkhttps://string-db.org/network/261317.BCTU_272Cell division protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of t [...]
rpiA protein networkhttps://string-db.org/network/261317.BCTU_273Ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
glnS protein networkhttps://string-db.org/network/261317.BCTU_277glutaminyl-tRNA synthetase; GlnS.
eno protein networkhttps://string-db.org/network/261317.BCTU_278Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
polA protein networkhttps://string-db.org/network/261317.BCTU_2795'-3' exonuclease domain of DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
engB protein networkhttps://string-db.org/network/261317.BCTU_280Putative GTPase, involved in coordination of cell cycle; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like [...]
typA protein networkhttps://string-db.org/network/261317.BCTU_281GTP-binding elongation factor family protein; TypA.
ygfZ protein networkhttps://string-db.org/network/261317.BCTU_282Folate-binding protein; YgfZ.
prfB protein networkhttps://string-db.org/network/261317.BCTU_283Peptide chain release factor RF-2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.
lysS protein networkhttps://string-db.org/network/261317.BCTU_284lysyl-tRNA synthetase; LysS; Belongs to the class-II aminoacyl-tRNA synthetase family.
lysA protein networkhttps://string-db.org/network/261317.BCTU_285Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
miaB protein networkhttps://string-db.org/network/261317.BCTU_286Bifunctional enzyme involved in thiolation and methylation of tRNA; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylal [...]
ybeY protein networkhttps://string-db.org/network/261317.BCTU_287Conserved hypothetical protein, Predicted metal-dependent hydrolase; YbeY.
leuS protein networkhttps://string-db.org/network/261317.BCTU_288leucyl-tRNA synthetase; LeuS; Belongs to the class-I aminoacyl-tRNA synthetase family.
sirA protein networkhttps://string-db.org/network/261317.BCTU_290Two-component response regulator; DNA polymerase III, delta subunit; Belongs to the sulfur carrier protein TusA family.
asd protein networkhttps://string-db.org/network/261317.BCTU_291Aspartate-semialdehyde dehydrogenase; Asd; Belongs to the aspartate-semialdehyde dehydrogenase family.
yhgn protein networkhttps://string-db.org/network/261317.BCTU_292Putative integral membrane protein; Yhgn.
pgk protein networkhttps://string-db.org/network/261317.BCTU_293Phosphoglycerate kinase; Pgk; Belongs to the phosphoglycerate kinase family.
fba protein networkhttps://string-db.org/network/261317.BCTU_294Fructose-1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphos [...]
yggB protein networkhttps://string-db.org/network/261317.BCTU_295Component of the MscS (small mechanosensitive ion channel); YggB.
recC protein networkhttps://string-db.org/network/261317.BCTU_296Exodeoxyribonuclease V, gamma chain; RecC.
nusB protein networkhttps://string-db.org/network/261317.BCTU_300tRNA-Met; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) op [...]
yccK protein networkhttps://string-db.org/network/261317.BCTU_301Putative sulfite reductase subunit protein; Part of a sulfur-relay system.
cyoE protein networkhttps://string-db.org/network/261317.BCTU_302Protoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
cyoC protein networkhttps://string-db.org/network/261317.BCTU_303Cytochrome o ubiquinol oxidase subunit III; CyoC.
cyoB protein networkhttps://string-db.org/network/261317.BCTU_304Cytochrome o ubiquinol oxidase subunit I; CyoB; Belongs to the heme-copper respiratory oxidase family.
cyoA protein networkhttps://string-db.org/network/261317.BCTU_305Cytochrome o ubiquinol oxidase subunit II; CyoA.
bolA protein networkhttps://string-db.org/network/261317.BCTU_306Transcriptional activator of morphogenic pathway; BolA; Belongs to the BolA/IbaG family.
clpP protein networkhttps://string-db.org/network/261317.BCTU_307ATP-dependent Clp protease proteolytic subunit; ClpP.
clpX protein networkhttps://string-db.org/network/261317.BCTU_308ATP-dependent protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the ab [...]
lon protein networkhttps://string-db.org/network/261317.BCTU_309ATP-dependent protease LA; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for [...]
dnaX protein networkhttps://string-db.org/network/261317.BCTU_311DNA polymerase III subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' [...]
ybaB protein networkhttps://string-db.org/network/261317.BCTU_312Hypothetical protein; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.
htpG protein networkhttps://string-db.org/network/261317.BCTU_313Heat shock protein 90; Molecular chaperone. Has ATPase activity.
adk protein networkhttps://string-db.org/network/261317.BCTU_314Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolis [...]
folD protein networkhttps://string-db.org/network/261317.BCTU_3165,10-methylene-tetrahydrofolate dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate [...]
cysS protein networkhttps://string-db.org/network/261317.BCTU_317cysteinyl-tRNA synthetase; CysS; Belongs to the class-I aminoacyl-tRNA synthetase family.
yebD protein networkhttps://string-db.org/network/261317.BCTU_318Hypothetical protein; YebD; Belongs to the UPF0250 family.
cspE protein networkhttps://string-db.org/network/261317.BCTU_319Cold shock protein CspE; CspE.
def protein networkhttps://string-db.org/network/261317.BCTU_324Polypeptide deformylase; AroE.
fmt protein networkhttps://string-db.org/network/261317.BCTU_325methionyl-tRNA formyltransferase; Fmt.
rplQ protein networkhttps://string-db.org/network/261317.BCTU_32650S ribosomal protein L17; RplQ.
rpoA protein networkhttps://string-db.org/network/261317.BCTU_327RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
rpsD protein networkhttps://string-db.org/network/261317.BCTU_32830S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
rpsK protein networkhttps://string-db.org/network/261317.BCTU_32930S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belon [...]
rpsM protein networkhttps://string-db.org/network/261317.BCTU_33030S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 [...]
rpmJ protein networkhttps://string-db.org/network/261317.BCTU_33150S ribosomal protein L36; RpmJ; Belongs to the bacterial ribosomal protein bL36 family.
secY protein networkhttps://string-db.org/network/261317.BCTU_332Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at t [...]
rplO protein networkhttps://string-db.org/network/261317.BCTU_33350S ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.
rpmD protein networkhttps://string-db.org/network/261317.BCTU_33450S ribosomal subunit protein L30; RpmD.
rpsE protein networkhttps://string-db.org/network/261317.BCTU_33530S ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 fam [...]
rplR protein networkhttps://string-db.org/network/261317.BCTU_33650S ribosomal protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protubera [...]
rplF protein networkhttps://string-db.org/network/261317.BCTU_33750S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the t [...]
rpsH protein networkhttps://string-db.org/network/261317.BCTU_33830S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to [...]
rpsN protein networkhttps://string-db.org/network/261317.BCTU_33930S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the un [...]
rplE protein networkhttps://string-db.org/network/261317.BCTU_34050S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance [...]
rplX protein networkhttps://string-db.org/network/261317.BCTU_34150S ribosomal protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.
rplN protein networkhttps://string-db.org/network/261317.BCTU_34250S ribosomal protein L14; RplN.
rpsQ protein networkhttps://string-db.org/network/261317.BCTU_34330S ribosomal protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.
rpmC protein networkhttps://string-db.org/network/261317.BCTU_34450S ribosomal protein L29; RpmC; Belongs to the universal ribosomal protein uL29 family.
rplP protein networkhttps://string-db.org/network/261317.BCTU_34550S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family.
rpsC protein networkhttps://string-db.org/network/261317.BCTU_34630S ribosomal protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family.
rplV protein networkhttps://string-db.org/network/261317.BCTU_34750S ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wal [...]
rpsS protein networkhttps://string-db.org/network/261317.BCTU_34830S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
rplB protein networkhttps://string-db.org/network/261317.BCTU_34950S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It [...]
rplW protein networkhttps://string-db.org/network/261317.BCTU_35050S ribosomal protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main dock [...]
rplD protein networkhttps://string-db.org/network/261317.BCTU_35150S ribosomal protein L4; Forms part of the polypeptide exit tunnel.
rplc protein networkhttps://string-db.org/network/261317.BCTU_35250S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
rpsJ protein networkhttps://string-db.org/network/261317.BCTU_35330S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
tufB protein networkhttps://string-db.org/network/261317.BCTU_354Elongation factor EF-Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
fusA protein networkhttps://string-db.org/network/261317.BCTU_355Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- [...]
rpsG protein networkhttps://string-db.org/network/261317.BCTU_35630S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit inte [...]
rpsL protein networkhttps://string-db.org/network/261317.BCTU_35730S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S an [...]
yheL protein networkhttps://string-db.org/network/261317.BCTU_358Sulfur transfer complex subunit TusB; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
yheM protein networkhttps://string-db.org/network/261317.BCTU_359Sulfur transfer complex subunit TusC; YheM; Belongs to the DsrF/TusC family.
yheN protein networkhttps://string-db.org/network/261317.BCTU_360Sulfur transfer complex subunit TusD; YheN.
trpS protein networkhttps://string-db.org/network/261317.BCTU_361tryptophanyl-tRNA synthetase; TrpS; Belongs to the class-I aminoacyl-tRNA synthetase family.
rpe protein networkhttps://string-db.org/network/261317.BCTU_362Ribulose-phosphate 3-epimerase; Rpe; Belongs to the ribulose-phosphate 3-epimerase family.
aroB protein networkhttps://string-db.org/network/261317.BCTU_3633-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).
aroK protein networkhttps://string-db.org/network/261317.BCTU_364Shikimate kinase I; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
yhgI protein networkhttps://string-db.org/network/261317.BCTU_366Iron-sulfur cluster scaffold protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/ [...]
bioH protein networkhttps://string-db.org/network/261317.BCTU_367Carboxylesterase; BioH.
ssb protein networkhttps://string-db.org/network/261317.BCTU_368Single-strand DNA-binding protein; Ssb.
dusA protein networkhttps://string-db.org/network/261317.BCTU_369tRNA-dihydrouridine synthase A; DusA.
dnaB protein networkhttps://string-db.org/network/261317.BCTU_370Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DN [...]
yggH protein networkhttps://string-db.org/network/261317.BCTU_371Hypothetical protein; YggH.
mutY protein networkhttps://string-db.org/network/261317.BCTU_372A/G-specific adenine glycosylase; MutY.
dut protein networkhttps://string-db.org/network/261317.BCTU_376tRNA-Met; SbcB.
rplI protein networkhttps://string-db.org/network/261317.BCTU_37750S ribosomal protein L9; Binds to the 23S rRNA.
rpsR protein networkhttps://string-db.org/network/261317.BCTU_37830S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosom [...]
rpsF protein networkhttps://string-db.org/network/261317.BCTU_37930S ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA.
miaA protein networkhttps://string-db.org/network/261317.BCTU_380Delta(2)-isopentenylpyrophosphate tRNA-adenosine transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, lea [...]
orn protein networkhttps://string-db.org/network/261317.BCTU_381Oligoribonuclease; 3'-to-5' exoribonuclease specific for small oligoribonucleotides.
rpmE protein networkhttps://string-db.org/network/261317.BCTU_38350S ribosomal protein L31; Binds the 23S rRNA.
hslV protein networkhttps://string-db.org/network/261317.BCTU_384ATP-dependent protease peptidase subunit; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
hslU protein networkhttps://string-db.org/network/261317.BCTU_385ATP-dependent protease ATP-binding subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by [...]
fpr protein networkhttps://string-db.org/network/261317.BCTU_386ferredoxin--NADP reductase; Fpr.
dapF protein networkhttps://string-db.org/network/261317.BCTU_388Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of t [...]
rho protein networkhttps://string-db.org/network/261317.BCTU_392Transcription termination factor; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and releas [...]
trxA protein networkhttps://string-db.org/network/261317.BCTU_393Thioredoxin; TrxA; Belongs to the thioredoxin family.
rep protein networkhttps://string-db.org/network/261317.BCTU_394ATP-dependent DNA helicase; Rep.
ilvC protein networkhttps://string-db.org/network/261317.BCTU_395Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yie [...]
ilvD protein networkhttps://string-db.org/network/261317.BCTU_396Dihydroxy-acid dehydratase; IIvD; Belongs to the IlvD/Edd family.
iscS protein networkhttps://string-db.org/network/261317.BCTU_398Cysteine desulfurase; IscS.
iscU protein networkhttps://string-db.org/network/261317.BCTU_399Putative Fe-S assembly protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off [...]
hscB protein networkhttps://string-db.org/network/261317.BCTU_400Chaperone protein HscB; HscB; Belongs to the HscB family.
hscA protein networkhttps://string-db.org/network/261317.BCTU_401Heat shock protein HscA; HscA; Belongs to the heat shock protein 70 family.
fdx protein networkhttps://string-db.org/network/261317.BCTU_402Ferredoxin; Fdx.
engA protein networkhttps://string-db.org/network/261317.BCTU_403GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase [...]
yfgM protein networkhttps://string-db.org/network/261317.BCTU_404Hypothetical protein; YfgM.