STRING Database User Survey
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Welcome to STRING
Protein-Protein Interaction Networks
Functional Enrichment Analysis
Organisms
14094
Proteins
67.6 mio
Interactions
>20 bln
Search
Protein by name
Protein by sequence
Multiple proteins
Multiple sequences
Proteins with Values/Ranks
Organisms
Protein families ("COGs")
... by family name
... by protein name
... by protein sequence
... multiple protein names
... multiple sequences
Examples
Random entry
Search
Single Protein by Name / Identifier
Protein Name:
(examples:
#1
#2
#3
)
Organism:
auto-detect
Cancel
Select
Advanced Settings
Network Type:
full STRING network
physical subnetwork
Required score:
highest confidence (0.900)
high confidence (0.700)
medium confidence (0.400)
low confidence (0.150)
Size cutoff:
no more than 5 interactors
no more than 10 interactors
no more than 20 interactors
no more than 50 interactors
Search
Single Protein by Sequence
Amino Acid Sequence:
(examples:
#1
#2
#3
)
Organism:
auto-detect
Cancel
Select
Advanced Settings
Network Type:
full STRING network
physical subnetwork
Required score:
highest confidence (0.900)
high confidence (0.700)
medium confidence (0.400)
low confidence (0.150)
Size cutoff:
no more than 5 interactors
no more than 10 interactors
no more than 20 interactors
no more than 50 interactors
Search
Multiple Proteins by Names / Identifiers
List Of Names:
(one-per-line or CSV; examples:
#1
#2
#3
)
... or, upload a file:
Browse ...
Organism:
auto-detect
Cancel
Select
Advanced Settings
Network Type:
full STRING network
physical subnetwork
Required score:
highest confidence (0.900)
high confidence (0.700)
medium confidence (0.400)
low confidence (0.150)
FDR stringency:
high (1 percent)
medium (5 percent)
lenient (25 percent)
Search
Multiple Proteins by Sequences
Amino Acid Sequences:
(examples:
#1
#2
)
... or, upload a file:
Browse ...
Organism:
auto-detect
Cancel
Select
Advanced Settings
Network Type:
full STRING network
physical subnetwork
Required score:
highest confidence (0.900)
high confidence (0.700)
medium confidence (0.400)
low confidence (0.150)
FDR stringency:
high (1 percent)
medium (5 percent)
lenient (25 percent)
Search
Proteins with Values/Ranks - Functional Enrichment Analysis
Submit your entire experiment as a list of proteins - no cutoffs.
Behind each protein, put a meaningful value for ranking (fold-change, log-pvalue, abundance, ...).
Proteins with Values:
(one-per-line; examples:
#1
#2
#3
)
... or, upload a file:
Browse ...
Organism:
Cancel
Select
Advanced Settings
FDR stringency:
high (1 percent)
medium (5 percent)
lenient (25 percent)
Initial sort order:
enrichment score
significance
pathway size
contribute your query for community benchmarking (one-year delay)
Search
Organisms and Clades
Organism:
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Select
Show Info
Examples and Highlights
Example 1
show
FAA4 and its ten most confident interactors.
FAA4 in yeast is a long chain fatty acyl-CoA synthetase; see it connected to other synthetases as well as regulators.
Example 2
show
The 20 most frequently mutated human cancer genes.
These have a higher-than-expected degree of interconnectivity, and are enriched in characteristic molecular functions.
Example 3
show
A poorly characterized protein from Natronococcus.
It has no annotated domains or functions, but shows some intriguing connections to possible DNA-replication or -repair proteins.
Protein Family by Name
Protein Family Name:
(examples:
#1
#2
#3
)
Search
Protein Family by Protein Name
Protein Name:
(examples:
#1
#2
#3
)
Organism:
auto-detect
Cancel
Select
Search
Protein Family by Protein Sequence
Amino Acid Sequence:
(examples:
#1
#2
#3
)
Organism:
auto-detect
Cancel
Select
Search
Protein Families by Multiple Names
List Of Names:
(examples:
#1
#2
#3
)
... or, upload a file:
Browse ...
Organism:
auto-detect
Cancel
Select
Search
Protein Families by Multiple Sequences
Amino Acid Sequences:
(examples:
#1
#2
)
... or, upload a file:
Browse ...
Organism:
auto-detect
Cancel
Select
Search
STRING Database User Survey