STRINGSTRING
Zfyve28 Zfyve28 Rbm46 Rbm46 Sh3rf3 Sh3rf3 Ppp1r7 Ppp1r7 Phf21b Phf21b Slitrk1 Slitrk1 Mrgprh Mrgprh BC055324 BC055324 Eps8l3 Eps8l3 Ankrd33b Ankrd33b Nkain3 Nkain3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
Gene Fusion
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[Homology]
Score
Zfyve28Lateral signaling target protein 2 homolog; Negative regulator of epidermal growth factor receptor (EGFR) signaling. Acts by promoting EGFR degradation in endosomes when not monoubiquitinated (By similarity); Belongs to the lst-2 family. (905 aa)    
Predicted Functional Partners:
Rbm46
Probable RNA-binding protein 46.
      
 0.743
Sh3rf3
E3 ubiquitin-protein ligase SH3RF3; Has E3 ubiquitin-protein ligase activity.
   
  
 0.525
Ppp1r7
Protein phosphatase 1 regulatory subunit 7; Regulatory subunit of protein phosphatase 1.
   
  
 0.481
Phf21b
PHD finger protein 21B.
   
  
 0.480
Slitrk1
SLIT and NTRK-like protein 1; It is involved in synaptogenesis and promotes excitatory synapse differentiation (By similarity). Enhances neuronal dendrite outgrowth ; Belongs to the SLITRK family.
   
  
 0.455
Mrgprh
Mas-related G-protein coupled receptor member H; Orphan receptor. May regulate nociceptor function and/or development, including the sensation or modulation of pain (By similarity); Belongs to the G-protein coupled receptor 1 family. Mas subfamily.
      
 0.451
BC055324
Uncharacterized protein C1orf112 homolog.
      
 0.447
Eps8l3
Epidermal growth factor receptor kinase substrate 8-like protein 3.
      
 0.424
Ankrd33b
Ankyrin repeat domain-containing protein 33B.
      
 0.403
Nkain3
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 3; Belongs to the NKAIN family.
   
  
 0.402
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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