STRINGSTRING
Mob3b Mob3b Lingo2 Lingo2 Ifnk Ifnk C9orf72 C9orf72 Eqtn Eqtn Lrrc19 Lrrc19
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Mob3bMOB kinase activator 3B; Modulates LATS1 expression in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. (216 aa)    
Predicted Functional Partners:
Lingo2
Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2.
      
 0.575
Ifnk
Interferon kappa; May play a role in the regulation of immune cell function.
      
 0.554
C9orf72
Guanine nucleotide exchange C9orf72 homolog; Component of the C9orf72-SMCR8 complex, a complex that has guanine nucleotide exchange factor (GEF) activity and regulates autophagy. In the complex, C9orf72 and SMCR8 probably constitute the catalytic subunits that promote the exchange of GDP to GTP, converting inactive GDP-bound RAB8A and RAB39B into their active GTP-bound form, thereby promoting autophagosome maturation (By similarity). The C9orf72-SMCR8 complex also acts as a regulator of autophagy initiation by interacting with the ATG1/ULK1 kinase complex and modulating its protein kin [...]
      
 0.495
Eqtn
Equatorin; Acrosomal membrane-anchored protein involved in the process of fertilization and in acrosome biogenesis.
 
    
 0.489
Lrrc19
Leucine-rich repeat-containing protein 19.
      
 0.487
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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